Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR038C
Length:
642
Number of sequences:
5887
Description:
YCR038C BUD5 SGDID:S000000634, Chr III from 199549-197621, Genome Release 64-1-1, reverse complement, Verified ORF, "GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q62245    1319   SOS1_MOUSE Son of sevenless homolog 1 OS=Mus ...2260.021     42     21     42GO:0005829; C:cytosol; TAS:Reactome.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IMP:MGI.
92Q32N25    594   GRP2A_XENLA RAS guanyl-releasing protein 2-A ...1950.027     41.2     26     43GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
93O77086    1571   C3G_DROME Guanine nucleotide-releasing factor...1890.031     41.2     19     43GO:0005622; C:intracellular; IEA:InterPro.
GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IMP:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0016203; P:muscle attachment; IMP:FlyBase.::GO:0007265; P:Ras protein signal transduction; IMP:UniProtKB.::GO:0032317; P:regulation of Rap GTPase activity; IDA:FlyBase.::GO:0045214; P:sarcomere organization; IMP:FlyBase.::GO:0007525; P:somatic muscle development; IMP:FlyBase.
94Q8IS11    944   GEFO_DICDI Ras guanine nucleotide exchange fa...1590.034     41.2     23     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
95O15211    777   RGL2_HUMAN Ral guanine nucleotide dissociatio...1940.035     40.8     24     41GO:0005622; C:intracellular; IEA:InterPro.
GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
96Q9R1K8    795   GRP1_RAT RAS guanyl-releasing protein 1 OS=Ra...2500.039     40.8     22     44GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; TAS:RGD.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
97A0JM95    475   RGF1A_XENTR Ras-GEF domain-containing family ...1420.04     40.4     23     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
98Q55FD8    1982   GEFV_DICDI Ras guanine nucleotide exchange fa...1860.075     40     25     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase.
99Q6DCK3    594   GRP2B_XENLA RAS guanyl-releasing protein 2-B ...1930.12     39.3     24     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
100Q1LZ97    673   GRP4_BOVIN RAS guanyl-releasing protein 4 OS=...2070.15     38.9     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016049; P:cell growth; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0009991; P:response to extracellular stimulus; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
101Q9Z1S3    795   GRP1_MOUSE RAS guanyl-releasing protein 1 OS=...1980.18     38.5     22     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
102O95267    797   GRP1_HUMAN RAS guanyl-releasing protein 1 OS=...2500.29     38.1     21     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005509; F:calcium ion binding; TAS:ProtInc.::GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:Reactome.::GO:0008289; F:lipid binding; TAS:ProtInc.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
103P14951    590   UVRC_BACSU UvrABC system protein C OS=Bacillu...1060.31     37.7     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009380; C:excinuclease repair complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
104A4IJ06    791   GRP1_XENTR RAS guanyl-releasing protein 1 OS=...2530.43     37.4     22     43GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
105Q3MIN7    710   RGL3_HUMAN Ral guanine nucleotide dissociatio...690.48     37.4     29     54GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
106Q5TJE5    780   RGL2_CANFA Ral guanine nucleotide dissociatio...1200.54     37     23     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
107Q8IZJ4    473   RGDSR_HUMAN Ral-GDS-related protein OS=Homo s...1110.55     37     24     49GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
108Q9P212    2302   PLCE1_HUMAN 1-phosphatidylinositol 4,5-bispho...1600.64     37     20     44GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:UniProtKB.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0017016; F:Ras GTPase binding; TAS:UniProtKB.::GO:0005057; F:receptor signaling protein activity; TAS:UniProtKB.
GO:0000187; P:activation of MAPK activity; IDA:UniProtKB.::GO:0007200; P:activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; IDA:UniProtKB.::GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; NAS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.::GO:0006651; P:diacylglycerol biosynthetic process; TAS:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; TAS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; NAS:UniProtKB.::GO:0032835; P:glomerulus development; IMP:HGNC.::GO:0007507; P:heart development; TAS:UniProtKB.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0006644; P:phospholipid metabolic process; IC:UniProtKB.::GO:0007265; P:Ras protein signal transduction; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.::GO:0046578; P:regulation of Ras protein signal transduction; IDA:UniProtKB.::GO:0006940; P:regulation of smooth muscle contraction; TAS:UniProtKB.
109A7Z7D7    590   UVRC_BACA2 UvrABC system protein C OS=Bacillu...1060.87     36.2     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009380; C:excinuclease repair complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
110Q6NTL4    791   GRP1_XENLA RAS guanyl-releasing protein 1 OS=...2532.1     35     22     43GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
111Q8ML92    106   AVE_DROME Protein aveugle OS=Drosophila melan...602.9     32.3     27     50GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0042675; P:compound eye cone cell differentiation; IMP:FlyBase.::GO:0001751; P:compound eye photoreceptor cell differentiation; IMP:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
112Q8K4S1    2282   PLCE1_MOUSE 1-phosphatidylinositol 4,5-bispho...1615.5     33.9     19     45GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0004435; F:phosphatidylinositol phospholipase C activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0000187; P:activation of MAPK activity; ISS:UniProtKB.::GO:0007200; P:activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; ISS:UniProtKB.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0046578; P:regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
113Q99P84    2281   PLCE1_RAT 1-phosphatidylinositol 4,5-bisphosp...1475.6     33.9     18     44GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0004435; F:phosphatidylinositol phospholipase C activity; ISS:UniProtKB.::GO:0017016; F:Ras GTPase binding; IDA:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0000187; P:activation of MAPK activity; ISS:UniProtKB.::GO:0007200; P:activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; ISS:UniProtKB.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; IDA:RGD.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0046578; P:regulation of Ras protein signal transduction; ISS:UniProtKB.
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