UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YCR009C

Length:

265

Number of sequences:

5887

Description:

YCR009C RVS161 SGDID:S000000602, Chr III from 131542-130745, Genome Release 64-1-1, reverse complement, Verified ORF, "Amphiphysin-like lipid raft protein; interacts with Rvs167p and regulates polarization of the actin cytoskeleton, endocytosis, cell polarity, cell fusion and viability following starvation or osmotic stress"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P25343	265	RV161_YEAST Reduced viability upon starvation...	265	0	543	100	100	GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0045121; C:membrane raft; IDA:SGD.
									GO:0008092; F:cytoskeletal protein binding; IPI:SGD.::GO:0019904; F:protein domain specific binding; IEA:InterPro.
									GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0031532; P:actin cytoskeleton reorganization; IMP:SGD.::GO:0000747; P:conjugation with cellular fusion; IMP:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0060988; P:lipid tube assembly; IDA:SGD.::GO:0006970; P:response to osmotic stress; IMP:SGD.::GO:0042594; P:response to starvation; IMP:SGD.
2	Q9UUM7	264	HOB3_SCHPO Protein hob3 OS=Schizosaccharomyce...	265	3e-112	331	58	77	GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase.
									GO:0008092; F:cytoskeletal protein binding; ISS:PomBase.::GO:0005096; F:GTPase activator activity; IGI:PomBase.
									GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0010687; P:site selection involved in cell cycle cytokinesis; IMP:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IGI:PomBase.
3	Q9JI08	253	BIN3_MOUSE Bridging integrator 3 OS=Mus muscu...	264	6e-18	84	28	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
									GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008104; P:protein localization; ISS:UniProtKB.::GO:0009826; P:unidimensional cell growth; ISS:UniProtKB.
4	Q5PPZ5	252	BIN3_XENLA Bridging integrator 3 homolog OS=X...	277	1e-17	83.2	27	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
									GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
5	Q68FW8	253	BIN3_RAT Bridging integrator 3 OS=Rattus norv...	254	2e-17	82.8	28	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
									GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
6	O74352	466	HOB1_SCHPO Protein hob1 OS=Schizosaccharomyce...	248	2e-17	84.7	27	46	GO:0051285; C:cell cortex of cell tip; TAS:PomBase.::GO:0031097; C:medial cortex; TAS:PomBase.
									GO:0051020; F:GTPase binding; NAS:PomBase.
									GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0006974; P:response to DNA damage stimulus; IGI:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase.
7	Q9NQY0	253	BIN3_HUMAN Bridging integrator 3 OS=Homo sapi...	264	4e-17	81.6	27	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
									GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.
									GO:0007015; P:actin filament organization; NAS:UniProtKB.::GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008104; P:protein localization; IMP:UniProtKB.::GO:0009826; P:unidimensional cell growth; IMP:UniProtKB.
8	P49418	695	AMPH_HUMAN Amphiphysin OS=Homo sapiens (Human...	211	0.00000000000009	74.3	28	50	GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
9	Q7TQF7	686	AMPH_MOUSE Amphiphysin OS=Mus musculus (Mouse...	211	0.00000000000009	74.3	28	50	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
									GO:0007612; P:learning; IMP:MGI.::GO:0048488; P:synaptic vesicle endocytosis; IMP:MGI.
10	O08838	683	AMPH_RAT Amphiphysin OS=Rattus norvegicus (Ra...	211	0.0000000000001	73.6	28	50	GO:0043679; C:axon terminus; IDA:RGD.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
									GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.
									GO:0045807; P:positive regulation of endocytosis; IMP:RGD.::GO:0043547; P:positive regulation of GTPase activity; IDA:RGD.
11	P50478	682	AMPH_CHICK Amphiphysin OS=Gallus gallus (Chic...	211	0.0000000000005	72	27	50	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:AgBase.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:AgBase.
12	P39743	482	RV167_YEAST Reduced viability upon starvation...	254	0.00000000001	67.8	26	46	GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.
									GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0060988; P:lipid tube assembly; IDA:SGD.
13	Q68FR2	507	BIN2_RAT Bridging integrator 2 OS=Rattus norv...	235	0.0000000007	62.4	25	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
14	Q9UBW5	565	BIN2_HUMAN Bridging integrator 2 OS=Homo sapi...	195	0.000001	52.8	25	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:IntAct.
15	D3Z6Q9	489	BIN2_MOUSE Bridging integrator 2 OS=Mus muscu...	235	0.000001	52.8	25	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
16	Q5ZKL7	476	BIN2_CHICK Bridging integrator 2 OS=Gallus ga...	195	0.000003	51.2	26	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
17	O08839	588	BIN1_RAT Myc box-dependent-interacting protei...	258	0.0004	45.1	21	42	GO:0043679; C:axon terminus; IDA:RGD.::GO:0044300; C:cerebellar mossy fiber; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IDA:RGD.::GO:0043196; C:varicosity; IDA:RGD.
									GO:0051020; F:GTPase binding; IPI:RGD.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045807; P:positive regulation of endocytosis; IMP:RGD.::GO:0043547; P:positive regulation of GTPase activity; IDA:RGD.
18	O08539	588	BIN1_MOUSE Myc box-dependent-interacting prot...	258	0.0004	45.1	21	42	GO:0005634; C:nucleus; IDA:MGI.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0042692; P:muscle cell differentiation; IMP:MGI.
19	O00499	593	BIN1_HUMAN Myc box-dependent-interacting prot...	261	0.002	43.1	21	41	GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
20	Q5W7F2	827	AGD3_ARATH ADP-ribosylation factor GTPase-act...	141	0.026	39.7	24	44	GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:TAIR.
									GO:0008060; F:ARF GTPase activator activity; IDA:TAIR.::GO:0035091; F:phosphatidylinositol binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0010087; P:phloem or xylem histogenesis; IMP:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0009733; P:response to auxin stimulus; IMP:TAIR.::GO:0010051; P:xylem and phloem pattern formation; IMP:TAIR.
21	A1IGU4	676	ARH37_MOUSE Rho guanine nucleotide exchange f...	180	0.41	35.8	23	38	GO:0005737; C:cytoplasm; IEA:InterPro.
									GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
									GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
22	Q54YJ7	454	XRCC4_DICDI DNA repair protein xrcc4 OS=Dicty...	91	1.1	34.3	30	47	GO:0005958; C:DNA-dependent protein kinase-DNA ligase 4 complex; ISS:dictyBase.
									GO:0003677; F:DNA binding; IEA:InterPro.
									GO:0006310; P:DNA recombination; ISS:dictyBase.::GO:0006302; P:double-strand break repair; ISS:dictyBase.
23	Q8AXU9	353	SH3G3_CHICK Endophilin-A3 OS=Gallus gallus (C...	241	1.9	33.5	23	45	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
									GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
24	A1IGU3	676	ARH37_RAT Rho guanine nucleotide exchange fac...	238	2.1	33.5	22	37	GO:0005737; C:cytoplasm; IEA:InterPro.
									GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
									GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
25	Q9FIT8	828	AGD1_ARATH ADP-ribosylation factor GTPase-act...	129	2.5	33.1	26	44	GO:0030139; C:endocytic vesicle; IDA:TAIR.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007010; P:cytoskeleton organization; IMP:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
26	A0PM87	304	Y816_MYCUA Putative S-adenosyl-L-methionine-d...	44	2.5	32.7	30	55
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
27	B2HCU3	304	Y1057_MYCMM Putative S-adenosyl-L-methionine-...	44	2.5	32.7	30	55
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
28	Q5VT06	3117	CE350_HUMAN Centrosome-associated protein 350...	74	2.9	33.1	26	47	GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
29	Q99961	368	SH3G1_HUMAN Endophilin-A2 OS=Homo sapiens (Hu...	157	2.9	32.7	23	48	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
									GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.
30	C4K3T9	288	PSD_HAMD5 Phosphatidylserine decarboxylase pr...	119	3.5	32.3	28	46
									GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:EC.
									GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
31	Q99963	347	SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens (Hu...	117	4.4	32.3	25	50	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
									GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
									GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.

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