Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCL043C
Length:
522
Number of sequences:
5887
Description:
YCL043C PDI1 SGDID:S000000548, Chr III from 50221-48653, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein disulfide isomerase; multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds; forms a complex with Mnl1p that has exomannosidase activity, processing unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2 which promotes degradation in the unfolded protein response"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q6GNG3    452   TMX3_XENLA Protein disulfide-isomerase TMX3 O...960.000001     54.7     31     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
92Q12404    318   MPD1_YEAST Protein disulfide-isomerase MPD1 O...1340.00000003     58.9     29     51GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0000324; C:fungal-type vacuole; IDA:SGD.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IDA:SGD.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:SGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IGI:SGD.
93Q50KB1    223   SEP2_EMIHU Protein disulfide-isomerase-like p...1050.0000000006     62.8     36     51GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0003756; F:protein disulfide isomerase activity; NAS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
94Q8BXZ1    456   TMX3_MOUSE Protein disulfide-isomerase TMX3 O...970.00000003     59.7     36     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
95P40557    701   EPS1_YEAST ER-retained PMA1-suppressing prote...670.19     38.1     33     60GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0051087; F:chaperone binding; IDA:SGD.::GO:0003756; F:protein disulfide isomerase activity; IMP:SGD.::GO:0051082; F:unfolded protein binding; IDA:SGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0006621; P:protein retention in ER lumen; IMP:SGD.
96Q96JJ7    454   TMX3_HUMAN Protein disulfide-isomerase TMX3 O...840.00000006     58.5     37     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
97Q5WA72    533   PDI15_ORYSJ Protein disulfide isomerase-like ...4670.000000000003     72.4     20     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0003756; F:protein disulfide isomerase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
98Q6NRT6    796   DJC10_XENLA DnaJ homolog subfamily C member 1...983.2     34.3     30     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IEA:InterPro.
99O13704    363   YEU5_SCHPO Thioredoxin domain-containing prot...1440.0000000002     65.9     35     54GO:0005788; C:endoplasmic reticulum lumen; NAS:PomBase.::GO:0005739; C:mitochondrion; IDA:PomBase.
GO:0003756; F:protein disulfide isomerase activity; ISS:PomBase.::GO:0015035; F:protein disulfide oxidoreductase activity; ISS:PomBase.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034605; P:cellular response to heat; IEP:PomBase.::GO:0006457; P:protein folding; IC:PomBase.
100Q498R3    793   DJC10_RAT DnaJ homolog subfamily C member 10 ...990.12     38.9     27     45GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006457; P:protein folding; IEA:InterPro.
101Q9DC23    793   DJC10_MOUSE DnaJ homolog subfamily C member 1...910.16     38.5     30     47GO:0034663; C:endoplasmic reticulum chaperone complex; ISS:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:UniProtKB.
GO:0001671; F:ATPase activator activity; IMP:UniProtKB.::GO:0051117; F:ATPase binding; IPI:UniProtKB.::GO:0051087; F:chaperone binding; IDA:UniProtKB.::GO:0015036; F:disulfide oxidoreductase activity; IDA:UniProtKB.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051787; F:misfolded protein binding; ISS:UniProtKB.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.
102Q5R875    454   TMX3_PONAB Protein disulfide-isomerase TMX3 O...840.0000002     57     36     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
103Q5R5L3    793   DJC10_PONAB DnaJ homolog subfamily C member 1...910.55     36.6     30     46GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IEA:InterPro.
104Q8IXB1    793   DJC10_HUMAN DnaJ homolog subfamily C member 1...910.57     36.6     30     46GO:0034663; C:endoplasmic reticulum chaperone complex; IDA:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0001671; F:ATPase activator activity; ISS:UniProtKB.::GO:0051117; F:ATPase binding; IPI:UniProtKB.::GO:0051087; F:chaperone binding; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051787; F:misfolded protein binding; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; IDA:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030433; P:ER-associated protein catabolic process; IMP:UniProtKB.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:UniProtKB.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
105O83889    105   THIO_TREPA Thioredoxin OS=Treponema pallidum ...670.001     42     33     57
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
106Q10N04    147   PDI51_ORYSJ Protein disulfide isomerase-like ...860.0005     43.9     31     50
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
107Q4N4N8    220   TXND_THEPA Thioredoxin domain-containing prot...860.00000003     57.8     37     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
108Q41864    167   TRXM_MAIZE Thioredoxin M-type, chloroplastic ...760.00008     46.6     30     55GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
109O00391    747   QSOX1_HUMAN Sulfhydryl oxidase 1 OS=Homo sapi...700.005     43.5     33     49GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0030173; C:integral to Golgi membrane; IDA:UniProtKB.
GO:0016971; F:flavin-linked sulfhydryl oxidase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IDA:UniProtKB.
110Q9UW02    106   THIO_COPCM Thioredoxin OS=Coprinus comatus (S...990.00003     47.4     27     56
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
111Q6PKC3    985   TXD11_HUMAN Thioredoxin domain-containing pro...1060.0007     46.2     29     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
112Q7KQL8    104   THIO_PLAF7 Thioredoxin OS=Plasmodium falcipar...830.00007     46.2     31     48
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
113O22022    102   THIO_CYAME Thioredoxin OS=Cyanidioschyzon mer...730.0001     45.4     30     53GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
114Q8JGM4    743   QSOX1_CHICK Sulfhydryl oxidase 1 OS=Gallus ga...1050.0007     45.8     30     50GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016971; F:flavin-linked sulfhydryl oxidase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; ISS:UniProtKB.
115Q9ZP20    172   TRXM5_ORYSJ Thioredoxin M5, chloroplastic OS=...810.000003     50.8     31     56GO:0009507; C:chloroplast; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0042744; P:hydrogen peroxide catabolic process; IMP:UniProtKB.::GO:0009657; P:plastid organization; IMP:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
116Q09433    115   THIO1_CAEEL Thioredoxin-1 OS=Caenorhabditis e...790.0001     45.8     30     52GO:0030424; C:axon; IDA:WormBase.::GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0030425; C:dendrite; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0031513; C:nonmotile primary cilium; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:WormBase.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IDA:WormBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
117P14949    104   THIO_BACSU Thioredoxin OS=Bacillus subtilis (...870.005     40.4     32     49
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
118Q9V429    114   THIO2_DROME Thioredoxin-2 OS=Drosophila melan...890.0003     44.3     31     47GO:0005634; C:nucleus; IDA:FlyBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IDA:UniProtKB.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0006979; P:response to oxidative stress; IMP:FlyBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
119Q8GYD1    146   PDI51_ARATH Protein disulfide-isomerase 5-1 O...1170.0003     44.7     30     45
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
120Q9LJU2    483   PDI53_ARATH Protein disulfide-isomerase 5-3 O...1170.00000006     58.9     28     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
121Q8K2W3    948   TXD11_MOUSE Thioredoxin domain-containing pro...1000.001     45.4     29     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
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