Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCL043C
Length:
522
Number of sequences:
5887
Description:
YCL043C PDI1 SGDID:S000000548, Chr III from 50221-48653, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein disulfide isomerase; multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds; forms a complex with Mnl1p that has exomannosidase activity, processing unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2 which promotes degradation in the unfolded protein response"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q9MAU6    447   PDI22_ARATH Protein disulfide-isomerase like ...1470.000000003     62.8     31     46GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0009505; C:plant-type cell wall; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
62P38660    439   PDIA6_MESAU Protein disulfide-isomerase A6 OS...1450.0000004     55.8     33     44GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0003756; F:protein disulfide isomerase activity; ISS:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0070527; P:platelet aggregation; ISS:UniProtKB.
63P38661    364   PDIA6_MEDSA Probable protein disulfide-isomer...1160.00000000000001     79     39     58GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
64Q75M08    366   PDI21_ORYSJ Protein disulfide isomerase-like ...1120.000000000002     72.4     35     59GO:0005783; C:endoplasmic reticulum; IEA:InterPro.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
65Q5R6T1    440   PDIA6_PONAB Protein disulfide-isomerase A6 OS...1040.0000002     57     33     54GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0003756; F:protein disulfide isomerase activity; ISS:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0070527; P:platelet aggregation; ISS:UniProtKB.
66Q67UF5    441   PDI23_ORYSJ Protein disulfide isomerase-like ...1070.0000001     57.4     34     50GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
67Q3T0L2    406   ERP44_BOVIN Endoplasmic reticulum resident pr...1200.0001     48.5     30     54GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
68Q9DAN1    588   PDILT_MOUSE Protein disulfide-isomerase-like ...5082e-18     92.4     24     43GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
69Q15084    440   PDIA6_HUMAN Protein disulfide-isomerase A6 OS...1040.0000002     57     33     54GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; TAS:ProtInc.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; TAS:ProtInc.
70Q00216    359   TIGA_ASPNG Protein disulfide-isomerase tigA O...1260.0000000000003     74.7     34     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
71Q63081    440   PDIA6_RAT Protein disulfide-isomerase A6 OS=R...1040.0000004     56.2     32     56GO:0005788; C:endoplasmic reticulum lumen; IDA:HGNC.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; TAS:RGD.::GO:0042470; C:melanosome; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; TAS:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0003756; F:protein disulfide isomerase activity; ISS:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0070527; P:platelet aggregation; ISS:UniProtKB.::GO:0006457; P:protein folding; TAS:RGD.
72Q922R8    440   PDIA6_MOUSE Protein disulfide-isomerase A6 OS...1040.0000005     55.8     32     55GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0003756; F:protein disulfide isomerase activity; ISS:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0070527; P:platelet aggregation; ISS:UniProtKB.
73Q86IA3    363   PDI1_DICDI Protein disulfide-isomerase 1 OS=D...1120.0000000000002     75.5     35     56GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IGI:dictyBase.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; ISS:dictyBase.
74Q5XI02    590   PDILT_RAT Protein disulfide-isomerase-like pr...1886e-18     90.9     34     52GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
75Q942L2    371   PDI22_ORYSJ Protein disulfide isomerase-like ...1060.0000000000001     76.3     35     60GO:0005783; C:endoplasmic reticulum; IEA:InterPro.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
76O48773    440   PDI23_ARATH Protein disulfide-isomerase 2-3 O...1070.0000000003     65.9     34     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
77Q92249    369   ERP38_NEUCR Protein disulfide-isomerase erp38...930.00000000002     69.3     41     57GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
78O13811    359   PDI2_SCHPO Protein disulfide-isomerase C17H9....880.00000001     60.5     32     59GO:0005783; C:endoplasmic reticulum; ISS:PomBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IMP:PomBase.::GO:0015035; F:protein disulfide oxidoreductase activity; IMP:PomBase.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034599; P:cellular response to oxidative stress; IMP:PomBase.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IMP:PomBase.
79Q869Z0    409   Y5025_DICDI Putative protein disulfide-isomer...1150.0000000005     65.1     33     55GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
80Q0E0I1    425   PDI53_ORYSJ Protein disulfide isomerase-like ...1110.00000000005     68.2     35     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
81Q14554    519   PDIA5_HUMAN Protein disulfide-isomerase A5 OS...810.0003     47.4     27     51GO:0005788; C:endoplasmic reticulum lumen; TAS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; TAS:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; TAS:UniProtKB.
82Q91W90    417   TXND5_MOUSE Thioredoxin domain-containing pro...910.0000000002     66.2     40     62GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
83Q0JD42    423   PDI52_ORYSJ Protein disulfide isomerase-like ...820.000000004     62.4     39     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
84Q5I0H9    517   PDIA5_RAT Protein disulfide-isomerase A5 OS=R...860.0003     47.4     33     56GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006950; P:response to stress; ISS:UniProtKB.
85Q921X9    517   PDIA5_MOUSE Protein disulfide-isomerase A5 OS...810.0001     48.5     28     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006950; P:response to stress; IDA:UniProtKB.
86Q2KIL5    521   PDIA5_BOVIN Protein disulfide-isomerase A5 OS...860.0004     46.6     31     56GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
87Q8NBS9    432   TXND5_HUMAN Thioredoxin domain-containing pro...880.00000000004     68.6     39     65GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0043202; C:lysosomal lumen; TAS:Reactome.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
88Q94F09    440   PDI52_ARATH Protein disulfide-isomerase 5-2 O...1100.0000000001     67     35     50GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009505; C:plant-type cell wall; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
89Q69SA9    485   PDI54_ORYSJ Protein disulfide isomerase-like ...960.005     43.1     31     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
90Q9T042    480   PDI54_ARATH Protein disulfide-isomerase 5-4 O...870.005     43.1     33     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
91Q6GNG3    452   TMX3_XENLA Protein disulfide-isomerase TMX3 O...960.000001     54.7     31     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
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