Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCL043C
Length:
522
Number of sequences:
5887
Description:
YCL043C PDI1 SGDID:S000000548, Chr III from 50221-48653, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein disulfide isomerase; multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds; forms a complex with Mnl1p that has exomannosidase activity, processing unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2 which promotes degradation in the unfolded protein response"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361Q58E26    287   TMX2_XENLA Thioredoxin-related transmembrane ...1390.87     35.4     25     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
362P29445    105   THIO1_DICDI Thioredoxin-1 OS=Dictyostelium di...670.99     33.5     28     52
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
363Q7JW12    271   TMX2_DROME Thioredoxin-related transmembrane ...1201.2     35     23     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
364A5UI29    579   DSBD_HAEIG Thiol:disulfide interchange protei...801.2     35.4     28     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
365Q4R5B4    296   TMX2_MACFA Thioredoxin-related transmembrane ...1441.3     35     24     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
366Q4QM23    579   DSBD_HAEI8 Thiol:disulfide interchange protei...801.4     35.4     28     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
367Q9XIF4    129   TRXH7_ARATH Thioredoxin H7 OS=Arabidopsis tha...742.9     32.7     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
368A5UDI9    579   DSBD_HAEIE Thiol:disulfide interchange protei...801.4     35.4     28     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
369O32171    106   YUSE_BACSU Thioredoxin-like protein yusE OS=B...931.8     32.7     26     46
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
370O23166    261   TR164_ARATH Thioredoxin-like protein HCF164, ...596.1     32.7     31     54GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.::GO:0031977; C:thylakoid lumen; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0010190; P:cytochrome b6f complex assembly; IMP:TAIR.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
371P44919    579   DSBD_HAEIN Thiol:disulfide interchange protei...801.9     35     28     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
372Q6P902    515   TXND2_MOUSE Thioredoxin domain-containing pro...631.9     35     27     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009434; C:microtubule-based flagellum; IDA:MGI.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006467; P:protein thiol-disulfide exchange; IDA:MGI.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
373Q7Y0D4    262   TR164_ORYSJ Thioredoxin-like protein HCF164, ...662     34.3     24     48
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
374Q9H1E5    349   TMX4_HUMAN Thioredoxin-related transmembrane ...1212.1     34.7     19     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
375Q2TBU2    296   TMX2_BOVIN Thioredoxin-related transmembrane ...1212.1     34.3     25     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
376Q5XIK2    295   TMX2_RAT Thioredoxin-related transmembrane pr...1322.2     34.3     23     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
377P77395    284   YBBN_ECOLI Uncharacterized protein ybbN OS=Es...862.5     34.3     23     47
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IDA:EcoliWiki.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IDA:EcoliWiki.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
378A5UG36    482   MLTF_HAEIG Membrane-bound lytic murein transg...1402.5     34.3     26     43GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.::GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
GO:0016837; F:carbon-oxygen lyase activity, acting on polysaccharides; IEA:EC.::GO:0008933; F:lytic transglycosylase activity; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0000270; P:peptidoglycan metabolic process; IEA:InterPro.
379Q4QNV4    482   MLTF_HAEI8 Membrane-bound lytic murein transg...1402.5     34.3     26     43GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.::GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
GO:0016837; F:carbon-oxygen lyase activity, acting on polysaccharides; IEA:EC.::GO:0008933; F:lytic transglycosylase activity; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0000270; P:peptidoglycan metabolic process; IEA:InterPro.
380Q487R3    608   DSBD_COLP3 Thiol:disulfide interchange protei...662.6     34.7     29     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
381Q9S795    501   BADH1_ARATH Betaine aldehyde dehydrogenase 1,...832.8     34.3     28     41GO:0005618; C:cell wall; IDA:TAIR.::GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0009516; C:leucoplast; IDA:TAIR.
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.
382Q4K909    583   DSBD_PSEF5 Thiol:disulfide interchange protei...1353.2     34.3     26     41GO:0016021; C:integral to membrane; ISS:JCVI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; ISS:JCVI.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0047134; F:protein-disulfide reductase activity; ISS:JCVI.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0017004; P:cytochrome complex assembly; ISS:JCVI.::GO:0022900; P:electron transport chain; ISS:JCVI.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
383Q9D710    295   TMX2_MOUSE Thioredoxin-related transmembrane ...1253.7     33.5     24     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
384P73920    180   TXLA_SYNY3 Thiol:disulfide interchange protei...374.9     32.7     35     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
385Q9JLZ1    337   GLRX3_RAT Glutaredoxin-3 OS=Rattus norvegicus...1674.9     33.5     19     39GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0005080; F:protein kinase C binding; IDA:RGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
386Q9KJZ3    578   DSBD_PSEUK Thiol:disulfide interchange protei...624.9     33.5     29     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
387Q5HVG7    567   DSBD_CAMJR Thiol:disulfide interchange protei...1246.3     33.1     24     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
388Q9PHR3    567   DSBD_CAMJE Thiol:disulfide interchange protei...1246.3     33.1     24     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
389P33770    452   HEMF_RHOS4 Coproporphyrinogen-III oxidase, an...616.9     33.1     30     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0051989; F:coproporphyrinogen dehydrogenase activity; IEA:EC.::GO:0004109; F:coproporphyrinogen oxidase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0030494; P:bacteriochlorophyll biosynthetic process; IEA:UniProtKB-KW.
390O76003    335   GLRX3_HUMAN Glutaredoxin-3 OS=Homo sapiens (H...768.9     32.3     21     49GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0010614; P:negative regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; ISS:UniProtKB.
records
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