Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCL043C
Length:
522
Number of sequences:
5887
Description:
YCL043C PDI1 SGDID:S000000548, Chr III from 50221-48653, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein disulfide isomerase; multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds; forms a complex with Mnl1p that has exomannosidase activity, processing unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2 which promotes degradation in the unfolded protein response"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P30101    505   PDIA3_HUMAN Protein disulfide-isomerase A3 OS...1110.00000000002     70.1     32     57GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; TAS:Reactome.
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0004629; F:phospholipase C activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003756; F:protein disulfide isomerase activity; TAS:ProtInc.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006457; P:protein folding; TAS:Reactome.::GO:0006606; P:protein import into nucleus; TAS:ProtInc.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.::GO:0006621; P:protein retention in ER lumen; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
32Q53LQ0    512   PDI11_ORYSJ Protein disulfide isomerase-like ...4771e-51     189     33     50GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0034975; P:protein folding in endoplasmic reticulum; IMP:UniProtKB.
33Q9XF61    507   PDI_DATGL Protein disulfide-isomerase OS=Dati...4732e-51     188     32     49GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
34D3Z6P0    527   PDIA2_MOUSE Protein disulfide-isomerase A2 OS...5066e-51     187     28     48GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; TAS:MGI.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
35P27773    505   PDIA3_MOUSE Protein disulfide-isomerase A3 OS...1220.0000000002     67     30     54GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.
36P09102    515   PDIA1_CHICK Protein disulfide-isomerase OS=Ga...5032e-49     183     30     48GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
37P52588    513   PDI_MAIZE Protein disulfide-isomerase OS=Zea ...4889e-49     181     31     49GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
38Q43116    498   PDI_RICCO Protein disulfide-isomerase OS=Rici...4841e-48     181     31     49GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
39P11598    505   PDIA3_RAT Protein disulfide-isomerase A3 OS=R...1220.00000000005     68.6     30     55GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
40Q13087    525   PDIA2_HUMAN Protein disulfide-isomerase A2 OS...4751e-46     175     28     46GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003756; F:protein disulfide isomerase activity; TAS:ProtInc.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IMP:HGNC.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; TAS:ProtInc.::GO:0006621; P:protein retention in ER lumen; TAS:ProtInc.::GO:0001666; P:response to hypoxia; IMP:HGNC.
41Q8VX13    579   PDI13_ARATH Protein disulfide isomerase-like ...1370.00008     48.9     28     49GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
42Q69ST6    545   PID13_ORYSJ Protein disulfide isomerase-like ...4753e-46     174     30     48GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
43Q17967    485   PDI1_CAEEL Protein disulfide-isomerase 1 OS=C...1080.000000000000004     81.6     41     56GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IDA:WormBase.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IDA:WormBase.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
44Q9FF55    597   PDI14_ARATH Protein disulfide isomerase-like ...4631e-45     173     29     46GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006979; P:response to oxidative stress; IDA:TAIR.
45P12244    508   GSBP_CHICK Dolichyl-diphosphooligosaccharide-...5251e-45     172     27     47GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0004579; F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
46Q7XRB5    517   PDI12_ORYSJ Protein disulfide isomerase-like ...5481e-44     169     29     47GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
47Q00002    436   PDI_ALTAL Protein disulfide-isomerase OS=Alte...460.00002     50.8     46     67GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0003756; F:protein disulfide isomerase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
48Q67IX6    563   PDI14_ORYSJ Protein disulfide isomerase-like ...5158e-44     167     29     48GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
49Q5RCH2    525   PDIA2_PONAB Protein disulfide-isomerase A2 OS...4792e-43     166     26     46GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
50P12865    497   BS2_TRYBB Bloodstream-specific protein 2 OS=T...4811e-38     151     26     47
GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
51Q95LM0    583   PDILT_MACFA Protein disulfide-isomerase-like ...4941e-25     114     26     45GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
52P34329    618   PDIA4_CAEEL Probable protein disulfide-isomer...1080.000000005     62.4     35     50GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IEP:WormBase.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
53Q8N807    584   PDILT_HUMAN Protein disulfide-isomerase-like ...4882e-25     113     25     45GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
54Q4VIT4    505   PDIA3_CHLAE Protein disulfide-isomerase A3 OS...1110.0000000005     65.5     35     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
55Q66GQ3    534   PDI16_ARATH Protein disulfide isomerase-like ...4615e-25     112     24     45GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
56A3KPF5    537   PDI15_ARATH Protein disulfide isomerase-like ...4841e-23     107     23     45GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
57Q9BS26    406   ERP44_HUMAN Endoplasmic reticulum resident pr...1190.0001     47.8     29     52GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.
GO:0003756; F:protein disulfide isomerase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; TAS:UniProtKB.::GO:0009100; P:glycoprotein metabolic process; IDA:UniProtKB.::GO:0006457; P:protein folding; IDA:UniProtKB.::GO:0006986; P:response to unfolded protein; IDA:UniProtKB.
58Q9D1Q6    406   ERP44_MOUSE Endoplasmic reticulum resident pr...1190.00003     49.7     31     52GO:0005788; C:endoplasmic reticulum lumen; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003756; F:protein disulfide isomerase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009100; P:glycoprotein metabolic process; ISS:UniProtKB.::GO:0006457; P:protein folding; ISS:UniProtKB.::GO:0006986; P:response to unfolded protein; ISS:UniProtKB.
59O22263    361   PDI21_ARATH Protein disulfide-isomerase like ...960.00000000000006     76.6     42     60GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0009505; C:plant-type cell wall; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009567; P:double fertilization forming a zygote and endosperm; IMP:TAIR.::GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0009553; P:embryo sac development; IMP:TAIR.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0048868; P:pollen tube development; IMP:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
60Q11067    440   PDIA6_CAEEL Probable protein disulfide-isomer...1420.0000006     55.5     28     49GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.
61Q9MAU6    447   PDI22_ARATH Protein disulfide-isomerase like ...1470.000000003     62.8     31     46GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0009505; C:plant-type cell wall; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
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