UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YCL043C

Length:

522

Number of sequences:

5887

Description:

YCL043C PDI1 SGDID:S000000548, Chr III from 50221-48653, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein disulfide isomerase; multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds; forms a complex with Mnl1p that has exomannosidase activity, processing unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2 which promotes degradation in the unfolded protein response"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
211	P97493	166	THIOM_MOUSE Thioredoxin, mitochondrial OS=Mus...	115	0.014	40	30	47	GO:0005739; C:mitochondrion; IDA:MGI.
									GO:0009055; F:electron carrier activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
212	P96611	106	YDBP_BACSU Thioredoxin-like protein ydbP OS=B...	89	0.43	34.7	19	49
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
213	P97615	166	THIOM_RAT Thioredoxin, mitochondrial OS=Rattu...	115	0.015	40	30	47	GO:0030425; C:dendrite; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0031669; P:cellular response to nutrient levels; IEP:RGD.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009725; P:response to hormone stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0006979; P:response to oxidative stress; IEP:RGD.::GO:0006810; P:transport; IEA:UniProtKB-KW.
214	P46843	458	TRXB_MYCLE Bifunctional thioredoxin reductase...	74	0.0003	47	30	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0019430; P:removal of superoxide radicals; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
215	Q1ZXE0	104	THIO4_DICDI Putative thioredoxin-4 OS=Dictyos...	85	0.00003	47.4	32	48
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; ISS:dictyBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
216	Q99757	166	THIOM_HUMAN Thioredoxin, mitochondrial OS=Hom...	119	0.013	40	29	46	GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
									GO:0009055; F:electron carrier activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
217	Q95108	166	THIOM_BOVIN Thioredoxin, mitochondrial OS=Bos...	115	0.059	38.1	30	47	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
218	Q8LEK4	221	TRL21_ARATH Thioredoxin-like 2-1, chloroplast...	65	0.00004	48.5	31	52	GO:0031969; C:chloroplast membrane; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
219	Q9PJK3	102	THIO_CHLMU Thioredoxin OS=Chlamydia muridarum...	103	0.0008	43.1	28	51
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
220	Q8KE49	109	THIO2_CHLTE Thioredoxin-2 OS=Chlorobium tepid...	73	0.005	40.4	29	49
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
221	P22217	103	TRX1_YEAST Thioredoxin-1 OS=Saccharomyces cer...	72	0.0002	44.7	32	53	GO:0005829; C:cytosol; IDA:SGD.::GO:0000324; C:fungal-type vacuole; IPI:SGD.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; TAS:SGD.::GO:0009263; P:deoxyribonucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IDA:SGD.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0080058; P:protein deglutathionylation; IDA:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006275; P:regulation of DNA replication; IGI:SGD.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IDA:SGD.::GO:0042144; P:vacuole fusion, non-autophagic; IDA:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.
222	O48737	179	TRXM1_ARATH Thioredoxin M1, chloroplastic OS=...	75	0.77	35	23	52	GO:0048046; C:apoplast; IDA:TAIR.::GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0010319; C:stromule; IDA:TAIR.::GO:0009579; C:thylakoid; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006109; P:regulation of carbohydrate metabolic process; IDA:UniProtKB.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0006979; P:response to oxidative stress; IGI:TAIR.::GO:0006810; P:transport; IEA:UniProtKB-KW.
223	Q7TN22	820	TXD16_MOUSE Thioredoxin domain-containing pro...	149	0.00006	49.7	26	52	GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
224	Q5UR29	137	TR548_MIMIV Thioredoxin-like protein R548 OS=...	30	0.0004	44.3	50	73
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
225	P07887	108	THIO2_CORNE Thioredoxin C-2 OS=Corynebacteriu...	76	0.00009	45.8	30	54
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
226	Q851R5	134	TRH22_ORYSJ Thioredoxin H2-2 OS=Oryza sativa ...	88	9	31.2	24	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
227	Q49WR2	104	THIO_STAS1 Thioredoxin OS=DSM 20229). GN=trxA...	83	0.0002	44.7	30	54
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
228	O51088	117	THIO_BORBU Thioredoxin OS=4680). GN=trxA Orde...	56	0.051	37.4	27	55
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
229	P29429	110	THIO_EMENI Thioredoxin OS=194 / M139) (Asperg...	93	0.0001	45.4	27	48
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
230	P87178	726	YB1D_SCHPO Uncharacterized protein C3D6.13c O...	80	0.005	43.5	28	51	GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0003756; F:protein disulfide isomerase activity; ISS:PomBase.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase.::GO:0006621; P:protein retention in ER lumen; ISS:PomBase.
231	P20857	111	THIO2_NOSS1 Thioredoxin-2 OS=Nostoc sp. (stra...	93	0.0004	43.9	25	54
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
232	O30974	112	THIO_MYCSM Thioredoxin OS=Mycobacterium smegm...	98	0.002	42	31	48
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
233	Q9XFH9	185	TRXF2_ARATH Thioredoxin F2, chloroplastic OS=...	47	0.027	39.7	38	62	GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0008047; F:enzyme activator activity; IDA:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
234	Q92JR5	105	THIO_RICCN Thioredoxin OS=Rickettsia conorii ...	80	0.0004	43.9	30	56
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
235	P73263	109	THIO2_SYNY3 Thioredoxin-like protein slr1139 ...	65	0.002	41.6	31	57
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
236	P34723	106	THIO_PENCH Thioredoxin OS=Penicillium chrysog...	82	0.001	42.7	32	55
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
237	Q8TFM8	121	THIO_FUSCU Thioredoxin-like protein OS=Fusari...	68	0.005	40.8	31	54
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
238	Q4UNK3	105	THIO_RICFE Thioredoxin OS=Rickettsia felis (s...	87	0.0002	44.7	31	51
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
239	P52227	102	THIO_CHLCV Thioredoxin OS=Chlamydophila cavia...	78	0.002	42	27	59
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
240	Q9XFH8	178	TRXF1_ARATH Thioredoxin F1, chloroplastic OS=...	88	0.038	38.9	33	52	GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0009534; C:chloroplast thylakoid; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006109; P:regulation of carbohydrate metabolic process; IDA:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
241	Q38879	133	TRXH2_ARATH Thioredoxin H2 OS=Arabidopsis tha...	101	0.006	40.4	27	47	GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0000103; P:sulfate assimilation; IGI:TAIR.::GO:0006810; P:transport; IEA:UniProtKB-KW.

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