Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCL043C
Length:
522
Number of sequences:
5887
Description:
YCL043C PDI1 SGDID:S000000548, Chr III from 50221-48653, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein disulfide isomerase; multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds; forms a complex with Mnl1p that has exomannosidase activity, processing unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2 which promotes degradation in the unfolded protein response"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q8K2W3    948   TXD11_MOUSE Thioredoxin domain-containing pro...1000.001     45.4     29     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
122P37395    107   THIO_CYACA Thioredoxin OS=Cyanidium caldarium...810.000001     51.2     37     57GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
123Q0Z7W6    278   TMX1_BOVIN Thioredoxin-related transmembrane ...1130.004     42.7     28     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
124P52233    108   THIO_THIFE Thioredoxin OS=Thiobacillus ferroo...810.000009     48.9     32     60
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
125A4FUW8    957   TXD11_BOVIN Thioredoxin domain-containing pro...1060.002     45.1     29     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
126P80579    105   THIO_ALIAC Thioredoxin OS=Alicyclobacillus ac...840.000002     51.2     35     57
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
127P48384    172   TRXM_PEA Thioredoxin M-type, chloroplastic OS...810.0004     44.7     30     53GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
128Q9H3N1    280   TMX1_HUMAN Thioredoxin-related transmembrane ...1130.0006     45.4     30     50GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:UniProtKB.
GO:0030612; F:arsenate reductase (thioredoxin) activity; NAS:UniProtKB.::GO:0015036; F:disulfide oxidoreductase activity; IDA:UniProtKB.
GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006260; P:DNA replication; NAS:UniProtKB.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:UniProtKB.::GO:0045321; P:leukocyte activation; NAS:UniProtKB.::GO:0045927; P:positive regulation of growth; NAS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006950; P:response to stress; NAS:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.
129P0AA30    109   THIO_SHIFL Thioredoxin-1 OS=Shigella flexneri...890.000005     49.7     34     52
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
130P0AA28    109   THIO_SALTY Thioredoxin-1 OS=Salmonella typhim...890.000005     49.7     34     52
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
131P0AA29    109   THIO_SALTI Thioredoxin-1 OS=Salmonella typhi....890.000005     49.7     34     52
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
132P0AA25    109   THIO_ECOLI Thioredoxin-1 OS=Escherichia coli ...890.000005     49.7     34     52
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:EcoCyc.
GO:0045454; P:cell redox homeostasis; IMP:EcoCyc.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
133P0AA26    109   THIO_ECOL6 Thioredoxin-1 OS=Escherichia coli ...890.000005     49.7     34     52
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
134P0AA27    109   THIO_ECO57 Thioredoxin-1 OS=Escherichia coli ...890.000005     49.7     34     52
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
135Q9ZP21    175   TRXM_WHEAT Thioredoxin M-type, chloroplastic ...850.00008     47     29     52GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
136Q8BND5    748   QSOX1_MOUSE Sulfhydryl oxidase 1 OS=Mus muscu...700.002     44.7     34     51GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0030173; C:integral to Golgi membrane; ISS:UniProtKB.
GO:0016971; F:flavin-linked sulfhydryl oxidase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; ISS:UniProtKB.
137P50338    109   THIO_GRIPA Thioredoxin OS=Griffithsia pacific...750.00009     45.8     31     52GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
138P42115    127   THIO_NEUCR Thioredoxin OS=1257 / FGSC 987). G...790.0007     43.5     30     53
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
139P23400    140   TRXM_CHLRE Thioredoxin M-type, chloroplastic ...950.0003     44.7     31     53GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
140O17486    107   THIO_ECHGR Thioredoxin OS=Echinococcus granul...790.069     37     27     42
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
141P51225    107   THIO_PORPU Thioredoxin OS=Porphyra purpurea. ...920.0004     43.9     26     53GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
142P10472    108   THIO_CHLLT Thioredoxin OS=Chlorobium limicola...740.0005     43.5     30     51
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
143Q6IUU3    750   QSOX1_RAT Sulfhydryl oxidase 1 OS=Rattus norv...620.006     43.1     34     53GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0030173; C:integral to Golgi membrane; ISS:UniProtKB.
GO:0016971; F:flavin-linked sulfhydryl oxidase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; ISS:UniProtKB.
144P57653    108   THIO_BUCAI Thioredoxin OS=(Acyrthosiphon pisu...860.001     42.7     27     53
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
145P00275    105   THIO1_CORNE Thioredoxin C-1 OS=Corynebacteriu...870.0002     45.1     32     53
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
146Q6XHI1    106   THIO2_DROYA Thioredoxin-2 OS=Drosophila yakub...890.00006     46.6     34     48
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
147Q69AB1    127   TXND8_RAT Thioredoxin domain-containing prote...670.074     37.4     30     52GO:0001669; C:acrosomal vesicle; IDA:RGD.::GO:0019861; C:flagellum; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:RGD.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0001675; P:acrosome assembly; IEP:RGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
148Q8VBT0    278   TMX1_MOUSE Thioredoxin-related transmembrane ...880.28     37     28     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
149Q3TMX7    692   QSOX2_MOUSE Sulfhydryl oxidase 2 OS=Mus muscu...590.036     40.4     39     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016972; F:thiol oxidase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
150Q6ZRP7    698   QSOX2_HUMAN Sulfhydryl oxidase 2 OS=Homo sapi...590.002     44.7     39     53GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016972; F:thiol oxidase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
151Q69AB2    127   TXND8_MOUSE Thioredoxin domain-containing pro...330.052     37.7     45     64GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
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