UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YCL030C

Length:

799

Number of sequences:

5887

Description:

YCL030C HIS4 SGDID:S000000535, Chr III from 68333-65934, Genome Release 64-1-1, reverse complement, Verified ORF, "Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphoribosyl-AMP cyclohydrolase, and histidinol dehydrogenase activities; catalyzes the second, third, ninth and tenth steps in histidine biosynthesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
211	Q39K91	438	HISX_BURS3 Histidinol dehydrogenase OS=/ NCIB...	438	3e-61	218	34	52
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
212	Q9A5V1	428	HISX_CAUCR Histidinol dehydrogenase OS=Caulob...	401	5e-61	217	36	53
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
213	Q970Y9	394	HISX_SULTO Histidinol dehydrogenase OS=Sulfol...	409	6e-61	216	37	57
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
214	O59667	417	HIS2_SCHPO Histidine biosynthesis bifunctiona...	232	9e-61	216	49	65	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IGI:PomBase.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; ISS:PomBase.
									GO:0000105; P:histidine biosynthetic process; IGI:PomBase.
215	Q5WIU9	424	HISX1_BACSK Histidinol dehydrogenase 1 OS=Bac...	409	3e-60	215	34	53
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
216	P60860	480	HISX_MYCPA Histidinol dehydrogenase OS=Mycoba...	452	4e-60	216	34	50
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
217	Q988P7	500	HISX2_RHILO Histidinol dehydrogenase 2 OS=Rhi...	408	5e-60	216	36	52
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
218	Q6AE76	436	HISX_LEIXX Histidinol dehydrogenase OS=Leifso...	429	7e-60	214	34	51
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
219	Q46N53	436	HPSN_CUPPJ Sulfopropanediol 3-dehydrogenase O...	427	3e-57	206	33	50
									GO:0004399; F:histidinol dehydrogenase activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:InterPro.
220	Q6KZD1	375	HISX_PICTO Histidinol dehydrogenase OS=100828...	370	3e-56	202	35	54
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
221	Q987C6	440	HISX3_RHILO Histidinol dehydrogenase 3 OS=Rhi...	409	2e-52	193	32	49
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
222	Q3J4H6	441	HISX2_RHOS4 Putative histidinol dehydrogenase...	441	9e-50	185	33	47
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
223	Q930I4	456	HISX2_RHIME Histidinol dehydrogenase 2 OS=mel...	417	1e-47	179	33	47
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
224	Q8GKZ1	167	HISX_SALEN Histidinol dehydrogenase OS=Salmon...	167	4e-41	153	50	66
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
225	Q9RQ82	201	HISX_BUCMH Histidinol dehydrogenase OS=Buchne...	203	5e-37	142	41	58
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
226	Q9RQ88	201	HISX_BUCDN Histidinol dehydrogenase OS=Buchne...	193	8e-34	134	39	60
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
227	Q9RQ85	201	HISX_BUCSC Histidinol dehydrogenase OS=Buchne...	189	1e-30	124	38	57
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
228	Q9L6I1	233	HISX_THIRO Histidinol dehydrogenase OS=Thioca...	227	2e-29	122	34	52
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
229	Q8DM88	214	HIS2_THEEB Histidine biosynthesis bifunctiona...	207	1e-21	99.4	36	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IEA:EC.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
230	O67780	205	HIS2_AQUAE Histidine biosynthesis bifunctiona...	226	2e-21	98.2	31	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IEA:EC.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
231	P06989	203	HIS2_ECOLI Histidine biosynthesis bifunctiona...	204	5e-21	97.1	34	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IEA:EC.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IGI:EcoCyc.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
232	Q8EFB6	211	HIS2_SHEON Histidine biosynthesis bifunctiona...	206	5e-21	97.1	34	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IEA:EC.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
233	Q8CXM8	215	HIS2_OCEIH Histidine biosynthesis bifunctiona...	196	6e-21	97.1	36	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IEA:EC.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
234	Q8ZY17	368	HISX_PYRAE Histidinol dehydrogenase OS=/ NBRC...	404	6e-21	99	28	44
									GO:0004399; F:histidinol dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
235	O24714	198	HIS2_KLEPN Histidine biosynthesis bifunctiona...	204	7e-21	96.7	35	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IEA:EC.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
236	Q8R886	205	HIS2_THETN Histidine biosynthesis bifunctiona...	196	1e-20	96.3	36	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IEA:EC.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
237	P58853	209	HIS2_PYRFU Histidine biosynthesis bifunctiona...	209	3e-20	95.1	34	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IEA:EC.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
238	P37793	203	HIS2_SHIFL Histidine biosynthesis bifunctiona...	204	3e-20	94.7	36	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IEA:EC.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
239	P74755	215	HIS2_SYNY3 Histidine biosynthesis bifunctiona...	174	4e-20	94.7	37	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IEA:EC.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
240	Q3Z0F9	203	HIS2_SHISS Histidine biosynthesis bifunctiona...	204	9e-20	93.2	35	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IEA:EC.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
241	Q9S5G3	203	HIS2_ECO57 Histidine biosynthesis bifunctiona...	204	9e-20	93.2	35	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004635; F:phosphoribosyl-AMP cyclohydrolase activity; IEA:EC.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.

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