Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCL027W
Length:
512
Number of sequences:
5887
Description:
YCL027W FUS1 SGDID:S000000532, Chr III from 71803-73341, Genome Release 64-1-1, Verified ORF, "Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P11710    512   FUS1_YEAST Nuclear fusion protein FUS1 OS=Sac...5120     1060     100     100GO:0005938; C:cell cortex; IMP:GOC.::GO:0005887; C:integral to plasma membrane; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0032065; P:cortical protein anchoring; IMP:SGD.::GO:0000755; P:cytogamy; IMP:SGD.::GO:0031385; P:regulation of termination of mating projection growth; IMP:SGD.
2Q62662    506   FRK_RAT Tyrosine-protein kinase FRK OS=Rattus...740.32     37.4     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0030154; P:cell differentiation; IEP:RGD.
3Q922K9    512   FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus ...680.4     37     28     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
4A2AAY5    908   SPD2B_MOUSE SH3 and PX domain-containing prot...720.42     37     28     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:UniProtKB.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IDA:UniProtKB.
GO:0060612; P:adipose tissue development; IMP:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; IMP:UniProtKB.::GO:0045600; P:positive regulation of fat cell differentiation; IMP:UniProtKB.::GO:0072657; P:protein localization in membrane; ISS:UniProtKB.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB.
5A2CG49    2964   KALRN_MOUSE Kalirin OS=Mus musculus (Mouse). ...570.92     36.2     37     51GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
6Q05688    640   IGF1R_BOVIN Insulin-like growth factor 1 rece...531.2     35.4     36     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005010; F:insulin-like growth factor-activated receptor activity; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB.
GO:0051389; P:inactivation of MAPKK activity; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051262; P:protein tetramerization; ISS:UniProtKB.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.
7O77774    392   NCF1_BOVIN Neutrophil cytosol factor 1 OS=Bos...411.5     35     34     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.
8P38041    980   BOB1_YEAST Protein BOB1 OS=Saccharomyces cere...571.5     35.4     26     51GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005543; F:phospholipid binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007118; P:budding cell apical bud growth; IGI:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD.
9P97814    415   PPIP1_MOUSE Proline-serine-threonine phosphat...491.6     35     33     57GO:0005826; C:actomyosin contractile ring; IDA:MGI.::GO:0032154; C:cleavage furrow; IDA:MGI.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; IDA:MGI.
GO:0003779; F:actin binding; IDA:MGI.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0019903; F:protein phosphatase binding; IDA:MGI.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IC:MGI.
10Q28832    811   LDLR_PIG Low-density lipoprotein receptor OS=...1222     35     27     46GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0034362; C:low-density lipoprotein particle; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
11Q12163    236   NBP2_YEAST NAP1-binding protein 2 OS=Saccharo...552.5     33.9     35     49GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; TAS:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006972; P:hyperosmotic response; IPI:SGD.::GO:0006469; P:negative regulation of protein kinase activity; IDA:SGD.::GO:0009408; P:response to heat; IMP:SGD.
12A1X283    911   SPD2B_HUMAN SH3 and PX domain-containing prot...722.5     34.7     26     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB.
GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; ISS:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0060612; P:adipose tissue development; ISS:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; ISS:UniProtKB.::GO:0072657; P:protein localization in membrane; IDA:UniProtKB.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB.
13A4FU49    640   SH321_HUMAN SH3 domain-containing protein 21 ...482.6     34.7     35     58
14P97924    2959   KALRN_RAT Kalirin OS=Rattus norvegicus (Rat)....572.7     34.7     35     49GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0007409; P:axonogenesis; IDA:RGD.::GO:0035556; P:intracellular signal transduction; IDA:HGNC.::GO:0050773; P:regulation of dendrite development; IDA:RGD.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
15Q4R729    692   SH321_MACFA SH3 domain-containing protein 21 ...483.3     34.3     35     58
16O43586    416   PPIP1_HUMAN Proline-serine-threonine phosphat...724.1     33.5     26     43GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016491; F:oxidoreductase activity; IEA:InterPro.
GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
17Q7TSG5    549   SH321_MOUSE SH3 domain-containing protein 21 ...786.8     33.1     31     46
18Q8TE67    593   ES8L3_HUMAN Epidermal growth factor receptor ...896.8     33.1     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
19Q92396    574   TYRO_PODAS Tyrosinase OS=Podospora anserina (...1169.9     32.7     28     43
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004503; F:monophenol monooxygenase activity; IEA:EC.
GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW.
records
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