Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCL018W
Length:
364
Number of sequences:
5887
Description:
YCL018W LEU2 SGDID:S000000523, Chr III from 91324-92418, Genome Release 64-1-1, Verified ORF, "Beta-isopropylmalate dehydrogenase (IMDH), catalyzes the third step in the leucine biosynthesis pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331P28241    369   IDH2_YEAST Isocitrate dehydrogenase [NAD] sub...3593e-24     105     28     48GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IDA:SGD.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0006102; P:isocitrate metabolic process; TAS:SGD.::GO:0006099; P:tricarboxylic acid cycle; TAS:SGD.
332Q99NA5    366   IDH3A_RAT Isocitrate dehydrogenase [NAD] subu...3634e-24     105     27     48GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; IDA:RGD.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD.
333Q1RJU4    483   IDH_RICBR Isocitrate dehydrogenase [NADP] OS=...3687e-24     105     26     45
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
334Q92IR7    483   IDH_RICCN Isocitrate dehydrogenase [NADP] OS=...3661e-23     105     27     47
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
335Q4UKR1    483   IDH_RICFE Isocitrate dehydrogenase [NADP] OS=...3691e-23     105     27     47
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
336Q9ZDR0    483   IDH_RICPR Isocitrate dehydrogenase [NADP] OS=...3609e-23     102     25     46
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
337Q68XA5    483   IDH_RICTY Isocitrate dehydrogenase [NADP] OS=...2816e-22     100     29     47
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
338Q93353    379   IDH3B_CAEEL Probable isocitrate dehydrogenase...3639e-22     98.2     27     48GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
339O13302    388   IDH1_AJECA Isocitrate dehydrogenase [NAD] sub...3647e-21     95.9     26     47GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
340O29610    412   IDH_ARCFU Isocitrate dehydrogenase [NADP] OS=...4058e-21     95.9     28     44
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
341O13696    356   IDH1_SCHPO Isocitrate dehydrogenase [NAD] sub...3709e-21     95.1     27     46GO:0005759; C:mitochondrial matrix; ISS:PomBase.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IMP:PomBase.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006537; P:glutamate biosynthetic process; IMP:PomBase.::GO:0006102; P:isocitrate metabolic process; IMP:PomBase.::GO:0006099; P:tricarboxylic acid cycle; IMP:PomBase.
342P28834    360   IDH1_YEAST Isocitrate dehydrogenase [NAD] sub...3551e-20     94.7     28     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005758; C:mitochondrial intermembrane space; TAS:Reactome.::GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IDA:SGD.::GO:0042645; C:mitochondrial nucleoid; IDA:SGD.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0006102; P:isocitrate metabolic process; TAS:SGD.::GO:0006099; P:tricarboxylic acid cycle; TAS:SGD.
343O77784    385   IDH3B_BOVIN Isocitrate dehydrogenase [NAD] su...3532e-19     92     26     48GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
344Q28479    385   IDH3B_MACFA Isocitrate dehydrogenase [NAD] su...3483e-19     91.3     26     48GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
345O43837    385   IDH3B_HUMAN Isocitrate dehydrogenase [NAD] su...3484e-19     90.9     26     48GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; TAS:ProtInc.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006102; P:isocitrate metabolic process; TAS:ProtInc.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
346Q68FX0    385   IDH3B_RAT Isocitrate dehydrogenase [NAD] subu...3535e-19     90.5     26     48GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; IDA:RGD.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD.
347Q5RBT4    385   IDH3B_PONAB Isocitrate dehydrogenase [NAD] su...3483e-18     88.2     26     47GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
348P96318    429   IDH_CALNO Isocitrate dehydrogenase [NADP] OS=...4101e-16     84.3     28     40
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
349Q59985    391   IDH_STRSL Isocitrate dehydrogenase [NADP] OS=...3802e-16     83.6     24     41
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
350P08200    416   IDH_ECOLI Isocitrate dehydrogenase [NADP] OS=...4140.000000000005     70.5     24     39
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0022900; P:electron transport chain; IMP:EcoliWiki.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IDA:EcoliWiki.
351O67480    426   IDH_AQUAE Isocitrate dehydrogenase [NADP] OS=...3770.000000000008     69.7     25     41
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
352P51553    393   IDH3G_HUMAN Isocitrate dehydrogenase [NAD] su...3600.00000000002     68.2     24     42GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
353Q8CNX4    422   IDH_STAES Isocitrate dehydrogenase [NADP] OS=...3930.00000000003     68.2     26     41
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
354Q5HNL1    422   IDH_STAEQ Isocitrate dehydrogenase [NADP] OS=...3930.00000000003     68.2     26     41
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
355P41564    355   IDH3G_MACFA Isocitrate dehydrogenase [NAD] su...3600.00000000003     67.8     24     42GO:0005739; C:mitochondrion; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
356Q58CP0    392   IDH3G_BOVIN Isocitrate dehydrogenase [NAD] su...3600.00000000003     67.8     24     42GO:0005739; C:mitochondrion; ISS:AgBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
357Q6GG12    422   IDH_STAAR Isocitrate dehydrogenase [NADP] OS=...3930.0000000002     65.1     24     40
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
358P70404    393   IDHG1_MOUSE Isocitrate dehydrogenase [NAD] su...3600.0000000003     65.1     24     42GO:0005739; C:mitochondrion; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
359P41565    393   IDHG1_RAT Isocitrate dehydrogenase [NAD] subu...3600.0000000004     64.7     24     42GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0045926; P:negative regulation of growth; IMP:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD.
360P56063    425   IDH_HELPY Isocitrate dehydrogenase [NADP] OS=...3060.0000000005     63.9     25     39
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
361Q9ZN36    425   IDH_HELPJ Isocitrate dehydrogenase [NADP] OS=...3060.000000001     62.8     25     39
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
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