Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCL017C
Length:
497
Number of sequences:
5887
Description:
YCL017C NFS1 SGDID:S000000522, Chr III from 94270-92777, Genome Release 64-1-1, reverse complement, Verified ORF, "Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis and in thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
451O95470    568   SGPL1_HUMAN Sphingosine-1-phosphate lyase 1 O...1570.72     36.2     26     39GO:0030176; C:integral to endoplasmic reticulum membrane; NAS:UniProtKB.
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; NAS:UniProtKB.
GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0006672; P:ceramide metabolic process; IDA:UniProtKB.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.::GO:0030149; P:sphingolipid catabolic process; NAS:UniProtKB.
452Q0AVH9    486   GCSPB_SYNWW Probable glycine dehydrogenase [d...940.8     35.8     26     52
GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
453P48320    585   DCE2_MOUSE Glutamate decarboxylase 2 OS=Mus m...1520.8     36.2     24     40GO:0030424; C:axon; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0004351; F:glutamate decarboxylase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0042136; P:neurotransmitter biosynthetic process; IEA:UniProtKB-KW.
454A5FMM4    425   KYNU_FLAJ1 Kynureninase OS=(Cytophaga johnson...1330.87     35.8     26     40GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
455O57709    502   GCSPB_PYRHO Probable glycine dehydrogenase [d...940.89     35.8     28     51
GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
456Q05683    585   DCE2_RAT Glutamate decarboxylase 2 OS=Rattus ...1500.96     35.8     25     41GO:0031225; C:anchored to membrane; IDA:RGD.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:RGD.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IDA:RGD.
GO:0016595; F:glutamate binding; IDA:RGD.::GO:0004351; F:glutamate decarboxylase activity; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; IDA:RGD.
GO:0006540; P:glutamate decarboxylation to succinate; IDA:RGD.::GO:0042136; P:neurotransmitter biosynthetic process; IEA:UniProtKB-KW.::GO:0042493; P:response to drug; IEP:RGD.
457Q6LXV6    380   SPSS_METMP O-phospho-L-seryl-tRNA:Cys-tRNA sy...830.98     35.4     27     54
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0043766; F:Sep-tRNA:Cys-tRNA synthase activity; IEA:EC.
GO:0006412; P:translation; IEA:UniProtKB-KW.
458Q9DBE0    493   CSAD_MOUSE Cysteine sulfinic acid decarboxyla...1890.98     35.8     22     40
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004782; F:sulfinoalanine decarboxylase activity; IEA:EC.
GO:0019452; P:L-cysteine catabolic process to taurine; TAS:MGI.
459P21549    392   SPYA_HUMAN Serine--pyruvate aminotransferase ...1010.98     35.4     25     45GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005782; C:peroxisomal matrix; IDA:UniProtKB.
GO:0008453; F:alanine-glyoxylate transaminase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:HGNC.::GO:0030170; F:pyridoxal phosphate binding; IMP:HGNC.::GO:0004760; F:serine-pyruvate transaminase activity; IEA:EC.
GO:0019265; P:glycine biosynthetic process, by transamination of glyoxylate; IDA:UniProtKB.::GO:0009436; P:glyoxylate catabolic process; IDA:UniProtKB.::GO:0042853; P:L-alanine catabolic process; IDA:UniProtKB.::GO:0006625; P:protein targeting to peroxisome; IMP:HGNC.
460A4FWT8    380   SPSS_METM5 O-phospho-L-seryl-tRNA:Cys-tRNA sy...831     35.4     27     54
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0043766; F:Sep-tRNA:Cys-tRNA synthase activity; IEA:EC.
GO:0006412; P:translation; IEA:UniProtKB-KW.
461Q49XY0    450   GCSPA_STAS1 Probable glycine dehydrogenase [d...901     35.4     30     49
GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
462A3CWM4    365   MFNA_METMJ L-tyrosine decarboxylase OS=Methan...1451.1     35.4     19     41
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
463P31030    392   SPYA_RABIT Serine--pyruvate aminotransferase ...851.1     35.4     26     48GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0008453; F:alanine-glyoxylate transaminase activity; IEA:EC.::GO:0004760; F:serine-pyruvate transaminase activity; IEA:EC.
464A8FF40    448   GCSPA_BACP2 Probable glycine dehydrogenase [d...881.3     35.4     33     50
GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
465Q9K936    488   GCSPB_BACHD Probable glycine dehydrogenase [d...941.3     35.4     28     50
GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
466B4M3C9    780   MOCOS_DROVI Molybdenum cofactor sulfurase OS=...1411.5     35.4     28     40
GO:0008265; F:Mo-molybdopterin cofactor sulfurase activity; ISS:UniProtKB.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
467Q80WP8    550   GADL1_MOUSE Glutamate decarboxylase-like prot...1461.5     35     23     40
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
468B6YT11    446   GCSPA_THEON Probable glycine dehydrogenase [d...1681.6     35     24     39
GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
469Q05329    585   DCE2_HUMAN Glutamate decarboxylase 2 OS=Homo ...1521.6     35     24     40GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0061202; C:clathrin sculpted gamma-aminobutyric acid transport vesicle membrane; TAS:Reactome.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0004351; F:glutamate decarboxylase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006540; P:glutamate decarboxylation to succinate; TAS:ProtInc.::GO:0042136; P:neurotransmitter biosynthetic process; IEA:UniProtKB-KW.::GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
470Q39M29    210   AZOR8_BURS3 FMN-dependent NADH-azoreductase 8...671.6     34.3     30     49
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016661; F:oxidoreductase activity, acting on other nitrogenous compounds as donors; IEA:InterPro.
471A6UUU3    385   SPSS_META3 O-phospho-L-seryl-tRNA:Cys-tRNA sy...731.7     34.7     26     53
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0043766; F:Sep-tRNA:Cys-tRNA synthase activity; IEA:EC.
GO:0006412; P:translation; IEA:UniProtKB-KW.
472Q9VRA2    781   MOCOS_DROME Molybdenum cofactor sulfurase OS=...502.1     34.7     36     54
GO:0008265; F:Mo-molybdopterin cofactor sulfurase activity; IMP:UniProtKB.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.::GO:0006727; P:ommochrome biosynthetic process; IMP:FlyBase.
473A4IT57    428   KYNU_GEOTN Kynureninase OS=Geobacillus thermo...1922.3     34.3     23     41GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
474B4PYH5    780   MOCOS_DROYA Molybdenum cofactor sulfurase OS=...502.4     34.7     36     54
GO:0008265; F:Mo-molybdopterin cofactor sulfurase activity; ISS:UniProtKB.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
475B6YT12    502   GCSPB_THEON Probable glycine dehydrogenase [d...962.5     34.3     29     49
GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
476B3NY19    781   MOCOS_DROER Molybdenum cofactor sulfurase OS=...502.5     34.7     36     54
GO:0008265; F:Mo-molybdopterin cofactor sulfurase activity; ISS:UniProtKB.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
477Q65HG0    448   GCSPA_BACLD Probable glycine dehydrogenase [d...893     33.9     31     48
GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
478Q5V1B4    350   MFNA_HALMA L-tyrosine decarboxylase OS=B-1809...1733.3     33.9     22     40
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
479Q21657    709   MOCOS_CAEEL Molybdenum cofactor sulfurase OS=...2993.3     34.3     23     38
GO:0008265; F:Mo-molybdopterin cofactor sulfurase activity; ISS:UniProtKB.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
480A0PA85    594   DCE1_CANFA Glutamate decarboxylase 1 OS=Canis...1333.3     33.9     24     39
GO:0004351; F:glutamate decarboxylase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0042136; P:neurotransmitter biosynthetic process; IEA:UniProtKB-KW.
481P14748    594   DCE1_FELCA Glutamate decarboxylase 1 OS=Felis...1333.4     33.9     24     39
GO:0004351; F:glutamate decarboxylase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0042136; P:neurotransmitter biosynthetic process; IEA:UniProtKB-KW.
records
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