UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YCL017C

Length:

497

Number of sequences:

5887

Description:

YCL017C NFS1 SGDID:S000000522, Chr III from 94270-92777, Genome Release 64-1-1, reverse complement, Verified ORF, "Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis and in thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
421	Q0CZX6	463	KYNU2_ASPTN Kynureninase 2 OS=Aspergillus ter...	184	0.12	38.5	21	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
422	Q6ZQY3	521	GADL1_HUMAN Glutamate decarboxylase-like prot...	146	0.12	38.5	24	40
									GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
423	C0ZBW7	489	GCSPB_BREBN Probable glycine dehydrogenase [d...	94	0.12	38.5	28	52
									GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
424	O67193	439	GCSPA_AQUAE Probable glycine dehydrogenase [d...	136	0.15	38.1	25	42
									GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
425	B4H0S8	796	MOCOS_DROPE Molybdenum cofactor sulfurase OS=...	251	0.16	38.5	25	39
									GO:0008265; F:Mo-molybdopterin cofactor sulfurase activity; ISS:UniProtKB.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
									GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
426	Q58369	385	Y959_METJA Uncharacterized aminotransferase M...	76	0.17	38.1	30	51
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
427	Q5JJ82	384	MFNA_PYRKO L-tyrosine decarboxylase OS=(Therm...	188	0.18	37.7	21	40
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
428	C5A2X8	383	MFNA_THEGJ L-tyrosine decarboxylase OS=Thermo...	190	0.19	37.7	21	43
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
429	P31029	414	SPYA_CALJA Serine--pyruvate aminotransferase,...	91	0.22	37.7	24	47	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
									GO:0008453; F:alanine-glyoxylate transaminase activity; IEA:EC.::GO:0004760; F:serine-pyruvate transaminase activity; IEA:EC.
430	C5A7J1	448	GCSPA_THEGJ Probable glycine dehydrogenase [d...	179	0.25	37.4	23	39
									GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
431	B3MZN7	773	MOCOS_DROAN Molybdenum cofactor sulfurase OS=...	246	0.3	37.4	23	37
									GO:0008265; F:Mo-molybdopterin cofactor sulfurase activity; ISS:UniProtKB.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
									GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
432	A9AA73	380	SPSS_METM6 O-phospho-L-seryl-tRNA:Cys-tRNA sy...	83	0.31	37	28	54
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0043766; F:Sep-tRNA:Cys-tRNA synthase activity; IEA:EC.
									GO:0006412; P:translation; IEA:UniProtKB-KW.
433	P0CO53	453	KYNU_CRYNB Kynureninase OS=(Filobasidiella ne...	181	0.31	37.4	23	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
434	P0CO52	453	KYNU_CRYNJ Kynureninase OS=ATCC MYA-565) (Fil...	181	0.32	37.4	23	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
435	Q12285	212	MDY2_YEAST Ubiquitin-like protein MDY2 OS=Sac...	85	0.35	36.2	27	47	GO:0005634; C:nucleus; IDA:SGD.::GO:0072380; C:TRC complex; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0000753; P:cell morphogenesis involved in conjugation with cellular fusion; IMP:SGD.::GO:0006620; P:posttranslational protein targeting to membrane; IDA:SGD.::GO:0045048; P:protein insertion into ER membrane; IGI:SGD.
436	B2IGG3	307	DDL_BEII9 D-alanine--D-alanine ligase OS=8712...	59	0.39	36.6	39	56	GO:0005618; C:cell wall; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
437	B4JXP7	770	MOCOS_DROGR Molybdenum cofactor sulfurase OS=...	337	0.42	37	23	36
									GO:0008265; F:Mo-molybdopterin cofactor sulfurase activity; ISS:UniProtKB.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
									GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
438	Q8TV92	372	MFNA_METKA L-tyrosine decarboxylase OS=100938...	241	0.46	36.6	23	38
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
439	Q43908	510	DDC_ACIBA L-2,4-diaminobutyrate decarboxylase...	145	0.46	36.6	28	42
									GO:0033983; F:diaminobutyrate decarboxylase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
440	Q5RDP0	392	SPYA_PONAB Serine--pyruvate aminotransferase ...	103	0.57	36.2	24	46	GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
									GO:0008453; F:alanine-glyoxylate transaminase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004760; F:serine-pyruvate transaminase activity; IEA:EC.
441	P48321	585	DCE2_PIG Glutamate decarboxylase 2 OS=Sus scr...	150	0.59	36.6	25	41	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
									GO:0004351; F:glutamate decarboxylase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0042136; P:neurotransmitter biosynthetic process; IEA:UniProtKB-KW.
442	Q5R4G0	568	SGPL1_PONAB Sphingosine-1-phosphate lyase 1 O...	157	0.6	36.6	26	39	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; IEA:EC.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
443	A6VGH9	380	SPSS_METM7 O-phospho-L-seryl-tRNA:Cys-tRNA sy...	88	0.64	36.2	28	55
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0043766; F:Sep-tRNA:Cys-tRNA synthase activity; IEA:EC.
									GO:0006412; P:translation; IEA:UniProtKB-KW.
444	Q4PRC2	585	DCE2_CANFA Glutamate decarboxylase 2 OS=Canis...	150	0.65	36.2	25	41	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
									GO:0004351; F:glutamate decarboxylase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0042136; P:neurotransmitter biosynthetic process; IEA:UniProtKB-KW.
445	Q9UXT1	502	GCSPB_PYRAB Probable glycine dehydrogenase [d...	94	0.65	36.2	28	51
									GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0019464; P:glycine decarboxylation via glycine cleavage system; IEA:HAMAP.
446	O32148	416	PUCG_BACSU Purine catabolism protein PucG OS=...	76	0.67	36.2	29	41
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
									GO:0006144; P:purine base metabolic process; IEA:UniProtKB-KW.
447	P45545	361	YHFS_ECOLI Uncharacterized protein yhfS OS=Es...	143	0.68	36.2	27	43
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
448	A3LQD7	465	KYNU_PICST Kynureninase OS=NRRL Y-11545) (Yea...	108	0.69	36.2	27	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
449	Q8TZJ2	502	GCSPB_PYRFU Probable glycine dehydrogenase [d...	94	0.71	36.2	30	50
									GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
450	A4J9B1	413	GLYA_DESRM Serine hydroxymethyltransferase OS...	176	0.72	36.2	26	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
451	O95470	568	SGPL1_HUMAN Sphingosine-1-phosphate lyase 1 O...	157	0.72	36.2	26	39	GO:0030176; C:integral to endoplasmic reticulum membrane; NAS:UniProtKB.
									GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; NAS:UniProtKB.
									GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0006672; P:ceramide metabolic process; IDA:UniProtKB.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.::GO:0030149; P:sphingolipid catabolic process; NAS:UniProtKB.

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