Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCL008C
Length:
385
Number of sequences:
5887
Description:
YCL008C STP22 SGDID:S000000514, Chr III from 106853-105696, Genome Release 64-1-1, reverse complement, Verified ORF, "Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P25604    385   STP22_YEAST Suppressor protein STP22 of tempe...3850     789     100     100GO:0000813; C:ESCRT I complex; IDA:SGD.::GO:0009898; C:internal side of plasma membrane; IDA:SGD.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0045324; P:late endosome to vacuole transport; IMP:SGD.::GO:0006464; P:protein modification process; IEA:InterPro.::GO:0006612; P:protein targeting to membrane; IMP:UniProtKB.::GO:0006623; P:protein targeting to vacuole; IMP:UniProtKB.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IC:SGD.
2Q99816    390   TS101_HUMAN Tumor susceptibility gene 101 pro...3801e-22     101     26     46GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005771; C:multivesicular body; TAS:HGNC.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0043130; F:ubiquitin binding; TAS:HGNC.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0046788; P:egress of virus within host cell; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0046755; P:non-lytic virus budding; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IDA:HGNC.
3Q61187    391   TS101_MOUSE Tumor susceptibility gene 101 pro...3994e-20     94     25     43GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; IDA:MGI.
GO:0007050; P:cell cycle arrest; IDA:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0030216; P:keratinocyte differentiation; IDA:MGI.::GO:0008285; P:negative regulation of cell proliferation; IDA:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0046755; P:non-lytic virus budding; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IDA:MGI.
4Q6IRE4    391   TS101_RAT Tumor susceptibility gene 101 prote...3966e-20     93.6     25     43GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008333; P:endosome to lysosome transport; IMP:RGD.::GO:0046755; P:non-lytic virus budding; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
5Q9LHG8    398   ELC_ARATH Protein ELC OS=Arabidopsis thaliana...3490.0000000000006     73.2     22     41GO:0005769; C:early endosome; IDA:TAIR.::GO:0000813; C:ESCRT I complex; ISS:TAIR.::GO:0005770; C:late endosome; IDA:TAIR.
GO:0043130; F:ubiquitin binding; IDA:TAIR.
GO:0051301; P:cell division; IMP:TAIR.::GO:0006464; P:protein modification process; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0010091; P:trichome branching; IMP:TAIR.
6Q9FFY6    368   ELCL_ARATH Protein ELC-like OS=Arabidopsis th...3530.00000000001     69.3     22     41GO:0000813; C:ESCRT I complex; ISS:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006464; P:protein modification process; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
7Q6DBY5    471   UEVLD_DANRE Ubiquitin-conjugating enzyme E2 v...1070.0002     47     30     50
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006464; P:protein modification process; IEA:InterPro.::GO:0015031; P:protein transport; IEA:InterPro.
8Q66KB7    476   UEVLD_XENTR Ubiquitin-conjugating enzyme E2 v...1030.004     42.7     24     49
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006464; P:protein modification process; IEA:InterPro.::GO:0015031; P:protein transport; IEA:InterPro.
9Q7Z992    487   SST6_SCHPO ESCRT-I complex subunit vps23 OS=S...2340.012     41.2     25     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0000813; C:ESCRT I complex; ISS:PomBase.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; IDA:PomBase.
GO:0006897; P:endocytosis; IMP:PomBase.::GO:0006900; P:membrane budding; IC:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase.
10Q3U1V6    471   UEVLD_MOUSE Ubiquitin-conjugating enzyme E2 v...1320.019     40.8     23     45
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006464; P:protein modification process; IEA:InterPro.::GO:0015031; P:protein transport; IEA:InterPro.
11Q8IX04    471   UEVLD_HUMAN Ubiquitin-conjugating enzyme E2 v...1320.029     40     23     46
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006464; P:protein modification process; IEA:InterPro.::GO:0015031; P:protein transport; IEA:InterPro.
12O83325    620   MUTL_TREPA DNA mismatch repair protein mutL O...2630.31     37     20     37
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
13Q8WZ42    34350   TITIN_HUMAN Titin OS=Homo sapiens (Human). GN...481.3     35     35     54GO:0000794; C:condensed nuclear chromosome; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0031430; C:M band; IDA:BHF-UCL.::GO:0005865; C:striated muscle thin filament; IDA:BHF-UCL.::GO:0030018; C:Z disc; IDA:UniProtKB.
GO:0051015; F:actin filament binding; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IDA:BHF-UCL.::GO:0005516; F:calmodulin binding; TAS:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0051371; F:muscle alpha-actinin binding; IPI:BHF-UCL.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0002020; F:protease binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0043621; F:protein self-association; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0008307; F:structural constituent of muscle; TAS:UniProtKB.::GO:0031433; F:telethonin binding; ISS:BHF-UCL.
GO:0048739; P:cardiac muscle fiber development; IMP:BHF-UCL.::GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0055003; P:cardiac myofibril assembly; IMP:BHF-UCL.::GO:0007076; P:mitotic chromosome condensation; IEP:BHF-UCL.::GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0045859; P:regulation of protein kinase activity; IMP:BHF-UCL.::GO:0051592; P:response to calcium ion; IDA:BHF-UCL.::GO:0045214; P:sarcomere organization; IMP:BHF-UCL.::GO:0048769; P:sarcomerogenesis; IMP:BHF-UCL.::GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:BHF-UCL.::GO:0030240; P:skeletal muscle thin filament assembly; IMP:BHF-UCL.::GO:0006941; P:striated muscle contraction; TAS:UniProtKB.
14Q5R5I4    154   UB2L3_PONAB Ubiquitin-conjugating enzyme E2 L...711.7     33.5     30     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0071385; P:cellular response to glucocorticoid stimulus; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15P68037    154   UB2L3_MOUSE Ubiquitin-conjugating enzyme E2 L...711.7     33.5     30     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0071385; P:cellular response to glucocorticoid stimulus; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16P68036    154   UB2L3_HUMAN Ubiquitin-conjugating enzyme E2 L...711.7     33.5     30     48GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0071385; P:cellular response to glucocorticoid stimulus; IDA:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:UniProtKB.
17Q3MHP1    154   UB2L3_BOVIN Ubiquitin-conjugating enzyme E2 L...711.7     33.5     30     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0071385; P:cellular response to glucocorticoid stimulus; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18B1H063    569   SYP_UNCTG Proline--tRNA ligase OS=Uncultured ...512.7     33.9     31     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004827; F:proline-tRNA ligase activity; IEA:EC.
GO:0006433; P:prolyl-tRNA aminoacylation; IEA:InterPro.
19Q9Y103    839   TFP11_DROME Septin-interacting protein 1 OS=D...624.7     33.1     23     60GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
20O74196    147   UBC1_COLGL Ubiquitin-conjugating enzyme E2-16...895.8     31.6     31     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
21Q8K4K7    375   ABRA_RAT Actin-binding Rho-activating protein...727.7     32.3     29     49GO:0015629; C:actin cytoskeleton; ISS:HGNC.::GO:0030017; C:sarcomere; IDA:HGNC.
GO:0003779; F:actin binding; ISS:HGNC.
GO:0035025; P:positive regulation of Rho protein signal transduction; ISS:HGNC.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:HGNC.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22A4XHE0    485   SYE1_CALS8 Glutamate--tRNA ligase 1 OS=Caldic...999.2     32     26     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004818; F:glutamate-tRNA ligase activity; IEA:EC.
GO:0006424; P:glutamyl-tRNA aminoacylation; IEA:InterPro.
records
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