Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR290W
Length:
321
Number of sequences:
5887
Description:
YBR290W BSD2 SGDID:S000000494, Chr II from 782591-783556, Genome Release 64-1-1, Verified ORF, "Heavy metal ion homeostasis protein, facilitates trafficking of Smf1p and Smf2p metal transporters to the vacuole where they are degraded, controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38356    321   BSD2_YEAST Metal homeostatis protein BSD2 OS=...3210     664     100     100GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:SGD.
GO:0030001; P:metal ion transport; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
2Q9P3T9    277   BSD2_SCHPO Probable metal homeostasis protein...1246e-24     102     43     61GO:0005789; C:endoplasmic reticulum membrane; IC:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
GO:0006875; P:cellular metal ion homeostasis; IC:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006623; P:protein targeting to vacuole; ISS:PomBase.::GO:0010959; P:regulation of metal ion transport; ISS:PomBase.
3Q9BT67    221   NFIP1_HUMAN NEDD4 family-interacting protein ...510.39     35.4     31     55GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0004871; F:signal transducer activity; IMP:UniProtKB.
GO:0006879; P:cellular iron ion homeostasis; IMP:UniProtKB.::GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB.::GO:0051224; P:negative regulation of protein transport; IMP:UniProtKB.::GO:0032410; P:negative regulation of transporter activity; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; IMP:UniProtKB.
4Q5U2S1    221   NFIP1_RAT NEDD4 family-interacting protein 1 ...510.41     35.4     31     55GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
5Q8R0W6    221   NFIP1_MOUSE NEDD4 family-interacting protein ...510.43     35.4     31     55GO:0005938; C:cell cortex; IDA:MGI.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0030173; C:integral to Golgi membrane; IC:MGI.
GO:0050699; F:WW domain binding; IPI:MGI.
GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0032713; P:negative regulation of interleukin-4 production; IMP:MGI.::GO:0048294; P:negative regulation of isotype switching to IgE isotypes; IMP:MGI.::GO:0042130; P:negative regulation of T cell proliferation; IMP:MGI.::GO:0002829; P:negative regulation of type 2 immune response; IMP:MGI.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0048302; P:regulation of isotype switching to IgG isotypes; IMP:MGI.::GO:0045619; P:regulation of lymphocyte differentiation; IMP:MGI.::GO:0002761; P:regulation of myeloid leukocyte differentiation; IMP:MGI.
6Q6DGP4    210   NFI1L_DANRE NEDD4 family-interacting protein ...510.47     35     31     55GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
7Q6GLN5    212   NFIP1_XENLA NEDD4 family-interacting protein ...510.99     34.3     29     55GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
8Q4V786    211   NFIP1_XENTR NEDD4 family-interacting protein ...511     34.3     29     55GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
9Q91ZP6    311   NFIP2_MOUSE NEDD4 family-interacting protein ...543     33.1     26     54GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.
10Q720J5    603   UVRC_LISMF UvrABC system protein C OS=Listeri...804.8     32.7     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009380; C:excinuclease repair complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
11P56701    908   PSMD2_BOVIN 26S proteasome non-ATPase regulat...486.7     32.3     33     52GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
12Q5R9I6    908   PSMD2_PONAB 26S proteasome non-ATPase regulat...486.8     32.3     33     52GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
13Q13200    908   PSMD2_HUMAN 26S proteasome non-ATPase regulat...486.9     32.3     33     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
14Q8VDM4    908   PSMD2_MOUSE 26S proteasome non-ATPase regulat...487     32.3     33     52GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
15Q4FZT9    908   PSMD2_RAT 26S proteasome non-ATPase regulator...487.1     32.3     33     52GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
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