rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P38352 | 637 | SAF1_YEAST SCF-associated factor 1 OS=Sacchar... | 637 | 0 | 1330 | 100 | 100 | GO:0019005; C:SCF ubiquitin ligase complex; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0016567; P:protein ubiquitination; IMP:GOC.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD. | 2 | O74381 | 467 | POF9_SCHPO F-box protein pof9 OS=Schizosaccha... | 295 | 0.000000007 | 62 | 25 | 40 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 3 | O95714 | 4834 | HERC2_HUMAN E3 ubiquitin-protein ligase HERC2... | 53 | 3.5 | 34.7 | 42 | 57 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; NAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 4 | Q4U2R1 | 4836 | HERC2_MOUSE E3 ubiquitin-protein ligase HERC2... | 53 | 3.6 | 34.7 | 42 | 57 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:MGI. | 5 | P21827 | 482 | RCC1_YEAST Guanine nucleotide exchange factor... | 79 | 2 | 35 | 32 | 49 | GO:0000790; C:nuclear chromatin; IDA:SGD. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IMP:SGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.::GO:0000054; P:ribosomal subunit export from nucleus; IMP:SGD.::GO:0006407; P:rRNA export from nucleus; IMP:SGD. | 6 | Q6PAV2 | 1057 | HERC4_MOUSE Probable E3 ubiquitin-protein lig... | 135 | 2 | 35.4 | 22 | 39 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:UniProtKB. | 7 | P28745 | 539 | RCC1_SCHPO Protein pim1 OS=Schizosaccharomyce... | 25 | 7.5 | 33.1 | 52 | 68 | GO:0000790; C:nuclear chromatin; NAS:PomBase. | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IGI:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:PomBase.::GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0031291; P:Ran protein signal transduction; IGI:PomBase.::GO:0060623; P:regulation of chromosome condensation; IGI:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:PomBase.::GO:0006407; P:rRNA export from nucleus; ISS:PomBase.::GO:0090307; P:spindle assembly involved in mitosis; TAS:PomBase. | 8 | Q5PQN1 | 1057 | HERC4_RAT Probable E3 ubiquitin-protein ligas... | 135 | 0.7 | 37 | 24 | 39 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 9 | Q5GLZ8 | 1057 | HERC4_HUMAN Probable E3 ubiquitin-protein lig... | 135 | 5 | 33.9 | 23 | 39 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 10 | P23800 | 421 | RCC1_MESAU Regulator of chromosome condensati... | 117 | 3.1 | 34.3 | 30 | 42 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0031492; F:nucleosomal DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; ISS:UniProtKB. | 11 | Q8VE37 | 421 | RCC1_MOUSE Regulator of chromosome condensati... | 117 | 1.9 | 35 | 30 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0031492; F:nucleosomal DNA binding; ISS:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:MGI. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; ISS:UniProtKB. | 12 | Q15034 | 1050 | HERC3_HUMAN Probable E3 ubiquitin-protein lig... | 88 | 0.045 | 40.8 | 31 | 47 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 13 | Q9VR91 | 4912 | HERC2_DROME Probable E3 ubiquitin-protein lig... | 41 | 4.7 | 34.3 | 51 | 61 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 14 | P18754 | 421 | RCC1_HUMAN Regulator of chromosome condensati... | 117 | 0.32 | 37.7 | 32 | 43 | GO:0000794; C:condensed nuclear chromosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0031492; F:nucleosomal DNA binding; IDA:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IMP:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007052; P:mitotic spindle organization; IDA:UniProtKB.::GO:0007088; P:regulation of mitosis; IDA:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:UniProtKB.::GO:0051225; P:spindle assembly; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome. | 15 | P25183 | 424 | RCC1_XENLA Regulator of chromosome condensati... | 42 | 0.52 | 37 | 38 | 67 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 16 | Q9UII4 | 1024 | HERC5_HUMAN E3 ISG15--protein ligase HERC5 OS... | 38 | 1.6 | 35.8 | 39 | 66 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042296; F:ISG15 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032020; P:ISG15-protein conjugation; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0050688; P:regulation of defense response to virus; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW. | 17 | Q8IVU3 | 1022 | HERC6_HUMAN Probable E3 ubiquitin-protein lig... | 37 | 2.3 | 35 | 43 | 65 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 18 | Q5DX34 | 1392 | RPGRH_CAEEL X-linked retinitis pigmentosa GTP... | 160 | 0.54 | 37.4 | 28 | 41 | GO:0030424; C:axon; IDA:WormBase.::GO:0045202; C:synapse; IDA:WormBase. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019915; P:lipid storage; IMP:WormBase. | 19 | Q9CYF5 | 461 | WBS16_MOUSE Williams-Beuren syndrome chromoso... | 237 | 0.57 | 37 | 22 | 35 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | | 20 | Q6NXM2 | 531 | RCBT1_MOUSE RCC1 and BTB domain-containing pr... | 54 | 0.77 | 36.6 | 37 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | Q8NDN9 | 531 | RCBT1_HUMAN RCC1 and BTB domain-containing pr... | 55 | 0.82 | 36.6 | 35 | 56 | GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | E1BZR9 | 1173 | TCPR1_CHICK Tectonin beta-propeller repeat-co... | 162 | 1.1 | 36.2 | 26 | 41 | GO:0000421; C:autophagic vacuole membrane; ISS:UniProtKB.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB. | | | | | | | | | | GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0000046; P:autophagic vacuole fusion; ISS:UniProtKB. | 23 | P52499 | 464 | RCC1_CANAX Protein RCC1 OS=Candida albicans (... | 27 | 1.3 | 35.8 | 44 | 81 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 24 | Q6P798 | 551 | RCBT2_RAT RCC1 and BTB domain-containing prot... | 61 | 9.4 | 33.1 | 33 | 49 | | | | | | | | | | | | | | | | | | | | | | 25 | Q5RCZ7 | 551 | RCBT2_PONAB RCC1 and BTB domain-containing pr... | 27 | 1.6 | 35.4 | 48 | 70 | | | | | | | | | | | | | | | | | | | | | | 26 | O95199 | 551 | RCBT2_HUMAN RCC1 and BTB domain-containing pr... | 27 | 1.6 | 35.4 | 48 | 70 | | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | | 27 | Q99LJ7 | 551 | RCBT2_MOUSE RCC1 and BTB domain-containing pr... | 27 | 1.7 | 35.4 | 48 | 70 | | | | | | | | | | | | | | | | | | | | | | 28 | Q8SSY6 | 1887 | SPKUL_DICDI Bifunctional serine/threonine-pro... | 35 | 2.9 | 35 | 40 | 66 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 29 | Q17551 | 3766 | RPM1_CAEEL E3 ubiquitin-protein ligase rpm-1 ... | 55 | 2.5 | 35 | 38 | 60 | GO:0030424; C:axon; IDA:WormBase.::GO:0031594; C:neuromuscular junction; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:WormBase.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040011; P:locomotion; IGI:WormBase.::GO:0043409; P:negative regulation of MAPK cascade; IGI:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0031647; P:regulation of protein stability; IMP:WormBase.::GO:0050807; P:regulation of synapse organization; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 30 | Q9P258 | 522 | RCC2_HUMAN Protein RCC2 OS=Homo sapiens (Huma... | 114 | 2.7 | 34.7 | 29 | 46 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000236; P:mitotic prometaphase; TAS:Reactome. | 31 | Q7ZZC8 | 944 | NEK9_XENLA Serine/threonine-protein kinase Ne... | 60 | 6.6 | 33.5 | 38 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. |