Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR280C
Length:
637
Number of sequences:
5887
Description:
YBR280C SAF1 SGDID:S000000484, Chr II from 764697-762784, Genome Release 64-1-1, reverse complement, Verified ORF, "F-Box protein involved in proteasome-dependent degradation of Aah1p during entry of cells into quiescence; interacts with Skp1"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38352    637   SAF1_YEAST SCF-associated factor 1 OS=Sacchar...6370     1330     100     100GO:0019005; C:SCF ubiquitin ligase complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0016567; P:protein ubiquitination; IMP:GOC.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD.
2O74381    467   POF9_SCHPO F-box protein pof9 OS=Schizosaccha...2950.000000007     62     25     40GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005515; F:protein binding; IPI:UniProtKB.
3O95714    4834   HERC2_HUMAN E3 ubiquitin-protein ligase HERC2...533.5     34.7     42     57GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; NAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
4Q4U2R1    4836   HERC2_MOUSE E3 ubiquitin-protein ligase HERC2...533.6     34.7     42     57GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:MGI.
5P21827    482   RCC1_YEAST Guanine nucleotide exchange factor...792     35     32     49GO:0000790; C:nuclear chromatin; IDA:SGD.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IMP:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.::GO:0000054; P:ribosomal subunit export from nucleus; IMP:SGD.::GO:0006407; P:rRNA export from nucleus; IMP:SGD.
6Q6PAV2    1057   HERC4_MOUSE Probable E3 ubiquitin-protein lig...1352     35.4     22     39GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:UniProtKB.
7P28745    539   RCC1_SCHPO Protein pim1 OS=Schizosaccharomyce...257.5     33.1     52     68GO:0000790; C:nuclear chromatin; NAS:PomBase.
GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IGI:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:PomBase.::GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0031291; P:Ran protein signal transduction; IGI:PomBase.::GO:0060623; P:regulation of chromosome condensation; IGI:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:PomBase.::GO:0006407; P:rRNA export from nucleus; ISS:PomBase.::GO:0090307; P:spindle assembly involved in mitosis; TAS:PomBase.
8Q5PQN1    1057   HERC4_RAT Probable E3 ubiquitin-protein ligas...1350.7     37     24     39GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
9Q5GLZ8    1057   HERC4_HUMAN Probable E3 ubiquitin-protein lig...1355     33.9     23     39GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
10P23800    421   RCC1_MESAU Regulator of chromosome condensati...1173.1     34.3     30     42GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0031492; F:nucleosomal DNA binding; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; ISS:UniProtKB.
11Q8VE37    421   RCC1_MOUSE Regulator of chromosome condensati...1171.9     35     30     43GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0031492; F:nucleosomal DNA binding; ISS:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; ISS:UniProtKB.
12Q15034    1050   HERC3_HUMAN Probable E3 ubiquitin-protein lig...880.045     40.8     31     47GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
13Q9VR91    4912   HERC2_DROME Probable E3 ubiquitin-protein lig...414.7     34.3     51     61GO:0005622; C:intracellular; IEA:InterPro.
GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
14P18754    421   RCC1_HUMAN Regulator of chromosome condensati...1170.32     37.7     32     43GO:0000794; C:condensed nuclear chromosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0031492; F:nucleosomal DNA binding; IDA:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IMP:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007052; P:mitotic spindle organization; IDA:UniProtKB.::GO:0007088; P:regulation of mitosis; IDA:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:UniProtKB.::GO:0051225; P:spindle assembly; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.
15P25183    424   RCC1_XENLA Regulator of chromosome condensati...420.52     37     38     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
16Q9UII4    1024   HERC5_HUMAN E3 ISG15--protein ligase HERC5 OS...381.6     35.8     39     66GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0042296; F:ISG15 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032020; P:ISG15-protein conjugation; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0050688; P:regulation of defense response to virus; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
17Q8IVU3    1022   HERC6_HUMAN Probable E3 ubiquitin-protein lig...372.3     35     43     65GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
18Q5DX34    1392   RPGRH_CAEEL X-linked retinitis pigmentosa GTP...1600.54     37.4     28     41GO:0030424; C:axon; IDA:WormBase.::GO:0045202; C:synapse; IDA:WormBase.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0019915; P:lipid storage; IMP:WormBase.
19Q9CYF5    461   WBS16_MOUSE Williams-Beuren syndrome chromoso...2370.57     37     22     35GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
20Q6NXM2    531   RCBT1_MOUSE RCC1 and BTB domain-containing pr...540.77     36.6     37     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21Q8NDN9    531   RCBT1_HUMAN RCC1 and BTB domain-containing pr...550.82     36.6     35     56GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22E1BZR9    1173   TCPR1_CHICK Tectonin beta-propeller repeat-co...1621.1     36.2     26     41GO:0000421; C:autophagic vacuole membrane; ISS:UniProtKB.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.
GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0000046; P:autophagic vacuole fusion; ISS:UniProtKB.
23P52499    464   RCC1_CANAX Protein RCC1 OS=Candida albicans (...271.3     35.8     44     81GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
24Q6P798    551   RCBT2_RAT RCC1 and BTB domain-containing prot...619.4     33.1     33     49
25Q5RCZ7    551   RCBT2_PONAB RCC1 and BTB domain-containing pr...271.6     35.4     48     70
26O95199    551   RCBT2_HUMAN RCC1 and BTB domain-containing pr...271.6     35.4     48     70
GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:ProtInc.
27Q99LJ7    551   RCBT2_MOUSE RCC1 and BTB domain-containing pr...271.7     35.4     48     70
28Q8SSY6    1887   SPKUL_DICDI Bifunctional serine/threonine-pro...352.9     35     40     66GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
29Q17551    3766   RPM1_CAEEL E3 ubiquitin-protein ligase rpm-1 ...552.5     35     38     60GO:0030424; C:axon; IDA:WormBase.::GO:0031594; C:neuromuscular junction; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:WormBase.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040011; P:locomotion; IGI:WormBase.::GO:0043409; P:negative regulation of MAPK cascade; IGI:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0031647; P:regulation of protein stability; IMP:WormBase.::GO:0050807; P:regulation of synapse organization; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q9P258    522   RCC2_HUMAN Protein RCC2 OS=Homo sapiens (Huma...1142.7     34.7     29     46GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.
31Q7ZZC8    944   NEK9_XENLA Serine/threonine-protein kinase Ne...606.6     33.5     38     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
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