Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR279W
Length:
445
Number of sequences:
5887
Description:
YBR279W PAF1 SGDID:S000000483, Chr II from 761257-762594, Genome Release 64-1-1, Verified ORF, "Component of the Paf1p complex; binds to and modulates the activity of RNA polymerases I and II; required for expression of a subset of genes, including cell cycle-regulated genes; homolog of human PD2/hPAF1; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38351    445   PAF1_YEAST RNA polymerase II-associated prote...4450     899     100     100GO:0016593; C:Cdc73/Paf1 complex; IPI:SGD.::GO:0035327; C:transcriptionally active chromatin; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0000993; F:RNA polymerase II core binding; IPI:SGD.::GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; IDA:SGD.::GO:0001089; F:TFIIF-class binding transcription factor activity; IMP:SGD.
GO:0000183; P:chromatin silencing at rDNA; IMP:SGD.::GO:0070911; P:global genome nucleotide-excision repair; IMP:SGD.::GO:0031124; P:mRNA 3'-end processing; IMP:SGD.::GO:0045910; P:negative regulation of DNA recombination; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:2001255; P:positive regulation of histone H3-K36 trimethylation; IMP:SGD.::GO:2001165; P:positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues; IMP:SGD.::GO:2001209; P:positive regulation of transcription elongation from RNA polymerase I promoter; IDA:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:0031938; P:regulation of chromatin silencing at telomere; IMP:SGD.::GO:2001173; P:regulation of histone H2B conserved C-terminal lysine ubiquitination; IDA:SGD.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0000114; P:regulation of transcription involved in G1 phase of mitotic cell cycle; IMP:SGD.::GO:0090262; P:regulation of transcription-coupled nucleotide-excision repair; IGI:SGD.::GO:0006364; P:rRNA processing; IMP:SGD.::GO:0031126; P:snoRNA 3'-end processing; IMP:SGD.::GO:0001015; P:snoRNA transcription from an RNA polymerase II promoter; IMP:SGD.::GO:0006362; P:transcription elongation from RNA polymerase I promoter; IMP:SGD.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IMP:SGD.
2Q9US06    456   PAF1_SCHPO RNA polymerase II-associated prote...3610.000000000000004     80.9     25     45GO:0016593; C:Cdc73/Paf1 complex; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0016571; P:histone methylation; ISS:PomBase.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; ISS:PomBase.
3Q6P2Y1    520   PAF1_XENTR RNA polymerase II-associated facto...3400.000002     53.9     24     43GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.
GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4A2BD83    524   PAF1_XENLA RNA polymerase II-associated facto...3400.000005     52.4     24     42GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.
GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q8N7H5    531   PAF1_HUMAN RNA polymerase II-associated facto...4550.00006     48.9     24     42GO:0016593; C:Cdc73/Paf1 complex; IDA:UniProtKB.
GO:0000993; F:RNA polymerase II core binding; IDA:UniProtKB.
GO:0001711; P:endodermal cell fate commitment; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.::GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0006378; P:mRNA polyadenylation; IMP:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0031442; P:positive regulation of mRNA 3'-end processing; IMP:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6Q5RAX0    533   PAF1_PONAB RNA polymerase II-associated facto...4550.00008     48.5     24     42GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.
GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.
GO:0001711; P:endodermal cell fate commitment; ISS:UniProtKB.::GO:0006378; P:mRNA polyadenylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0031442; P:positive regulation of mRNA 3'-end processing; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7Q8K2T8    535   PAF1_MOUSE RNA polymerase II-associated facto...4540.0002     47.4     23     41GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.
GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.
GO:0001711; P:endodermal cell fate commitment; IMP:UniProtKB.::GO:0006378; P:mRNA polyadenylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0031442; P:positive regulation of mRNA 3'-end processing; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0019827; P:stem cell maintenance; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q2KJ14    532   PAF1_BOVIN RNA polymerase II-associated facto...4560.0002     47.4     24     42GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.
GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.
GO:0001711; P:endodermal cell fate commitment; ISS:UniProtKB.::GO:0006378; P:mRNA polyadenylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0031442; P:positive regulation of mRNA 3'-end processing; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q4V886    535   PAF1_RAT RNA polymerase II-associated factor ...4560.0004     46.2     23     42GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.
GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.
GO:0001711; P:endodermal cell fate commitment; ISS:UniProtKB.::GO:0006378; P:mRNA polyadenylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0031442; P:positive regulation of mRNA 3'-end processing; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q4U0S5    503   PAF1_DANRE RNA polymerase II-associated facto...3400.001     44.7     23     41GO:0016593; C:Cdc73/Paf1 complex; IDA:ZFIN.
GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.
GO:0007507; P:heart development; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11P90783    425   PAF1_CAEEL RNA polymerase II-associated facto...3990.7     35.8     21     41GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q09472    2414   EP300_HUMAN Histone acetyltransferase p300 OS...1050.92     35.8     22     44GO:0005813; C:centrosome; IDA:HPA.
GO:0050681; F:androgen receptor binding; IPI:BHF-UCL.::GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IDA:UniProtKB.::GO:0043967; P:histone H4 acetylation; IMP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0043923; P:positive regulation by host of viral transcription; IDA:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:BHF-UCL.::GO:0043627; P:response to estrogen stimulus; IDA:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13A4YCQ5    597   IF2P_METS5 Probable translation initiation fa...1013.9     33.5     26     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
14Q1D5X5    459   DER_MYXXD GTPase Der OS=Myxococcus xanthus (s...1254.2     33.5     27     42
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
15Q9QZM6    1181   NCKX1_RAT Sodium/potassium/calcium exchanger ...854.4     33.5     32     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008273; F:calcium, potassium:sodium antiporter activity; IEA:InterPro.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
records
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