UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR278W

Length:

201

Number of sequences:

5887

Description:

YBR278W DPB3 SGDID:S000000482, Chr II from 760294-760899, Genome Release 64-1-1, Verified ORF, "Third-largest subunit of DNA polymerase II (DNA polymerase epsilon), required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; mRNA abundance peaks at the G1/S boundary of the cell cycle"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P27344	201	DPB3_YEAST DNA polymerase epsilon subunit C O...	201	8e-142	400	100	100	GO:0008622; C:epsilon DNA polymerase complex; IDA:SGD.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003887; F:DNA-directed DNA polymerase activity; TAS:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0006273; P:lagging strand elongation; TAS:SGD.::GO:0006272; P:leading strand elongation; TAS:SGD.::GO:0006298; P:mismatch repair; TAS:SGD.::GO:0006289; P:nucleotide-excision repair; TAS:SGD.
2	Q6FXJ8	255	DPB3_CANGA DNA polymerase epsilon subunit C O...	174	4e-30	116	40	61	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
3	Q6CLM5	166	DPB3_KLULA DNA polymerase epsilon subunit C O...	138	4e-16	76.6	39	58	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
4	Q6BX14	277	DPB3_DEBHA DNA polymerase epsilon subunit C O...	97	0.000000000002	67.4	35	56	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
5	P40366	167	DLS1_YEAST Protein DLS1 OS=Saccharomyces cere...	46	0.00000005	53.5	59	72	GO:0008623; C:chromatin accessibility complex; IPI:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6	C6Y4D0	87	YCGV_SCHPO Putative transcription factor C16C...	79	0.000008	46.2	37	52	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7	A6QQ14	116	DPOE4_BOVIN DNA polymerase epsilon subunit 4 ...	80	0.00002	45.8	36	54
									GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
8	Q9NR33	117	DPOE4_HUMAN DNA polymerase epsilon subunit 4 ...	80	0.00002	45.4	36	54	GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.
									GO:0003887; F:DNA-directed DNA polymerase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.
9	Q9CQ36	118	DPOE4_MOUSE DNA polymerase epsilon subunit 4 ...	80	0.00002	45.4	36	54
									GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
10	Q6C6M5	114	DPB3_YARLI DNA polymerase epsilon subunit C O...	91	0.0004	42	29	57	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
11	Q10315	199	DPB3_SCHPO DNA polymerase epsilon subunit C O...	83	0.0005	43.1	25	60	GO:0000785; C:chromatin; NAS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031261; C:DNA replication preinitiation complex; IC:PomBase.::GO:0008622; C:epsilon DNA polymerase complex; IPI:PomBase.
									GO:0003887; F:DNA-directed DNA polymerase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0006261; P:DNA-dependent DNA replication; IMP:PomBase.
12	Q9FGP6	186	NFYC5_ARATH Nuclear transcription factor Y su...	82	0.004	40.4	29	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13	Q9NRG0	131	CHRC1_HUMAN Chromatin accessibility complex p...	80	0.02	37.4	30	49	GO:0008623; C:chromatin accessibility complex; NAS:UniProtKB.::GO:0008622; C:epsilon DNA polymerase complex; NAS:UniProtKB.
									GO:0003887; F:DNA-directed DNA polymerase activity; NAS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006338; P:chromatin remodeling; NAS:UniProtKB.
14	Q4PSE2	187	NFYC8_ARATH Nuclear transcription factor Y su...	114	0.024	38.1	26	48	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15	Q54DA1	550	NC2A_DICDI Dr1-associated corepressor homolog...	83	0.026	38.5	28	57	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16	Q9FGP8	212	NFYC7_ARATH Nuclear transcription factor Y su...	132	0.046	37.4	23	40	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17	Q2YDP3	205	NC2A_BOVIN Dr1-associated corepressor OS=Bos ...	80	0.05	37.4	24	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18	Q9D6N5	205	NC2A_MOUSE Dr1-associated corepressor OS=Mus ...	80	0.063	37	24	55	GO:0005634; C:nucleus; IDA:MGI.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IDA:MGI.
									GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19	A0JPP1	205	NC2A_RAT Dr1-associated corepressor OS=Rattus...	80	0.066	37	24	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20	Q14919	205	NC2A_HUMAN Dr1-associated corepressor OS=Homo...	80	0.082	36.6	24	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
									GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21	Q9JKP8	129	CHRC1_MOUSE Chromatin accessibility complex p...	80	0.14	35	30	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
22	Q9SMP0	234	NFYC1_ARATH Nuclear transcription factor Y su...	82	0.4	34.7	32	50	GO:0005634; C:nucleus; IDA:TAIR.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23	Q9FMV5	250	NFYC4_ARATH Nuclear transcription factor Y su...	82	0.59	33.9	32	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0009738; P:abscisic acid mediated signaling pathway; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24	Q9FGP7	202	NFYC6_ARATH Nuclear transcription factor Y su...	82	0.74	33.5	28	48	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25	Q8LCG7	199	NFYC2_ARATH Nuclear transcription factor Y su...	80	0.78	33.5	31	49	GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26	P70353	335	NFYC_MOUSE Nuclear transcription factor Y sub...	80	0.96	33.5	30	50	GO:0005667; C:transcription factor complex; IC:MGI.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
									GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27	Q5E9X1	335	NFYC_BOVIN Nuclear transcription factor Y sub...	80	0.98	33.5	30	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28	Q5RA23	335	NFYC_PONAB Nuclear transcription factor Y sub...	80	1	33.5	30	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29	Q62725	335	NFYC_RAT Nuclear transcription factor Y subun...	80	1	33.5	30	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30	Q13952	458	NFYC_HUMAN Nuclear transcription factor Y sub...	80	1.5	33.1	31	50	GO:0016602; C:CCAAT-binding factor complex; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-KW.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
									GO:0006457; P:protein folding; TAS:ProtInc.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31	Q9ZVL3	217	NFYC3_ARATH Nuclear transcription factor Y su...	82	3.5	31.6	29	45	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.

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