UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR276C

Length:

807

Number of sequences:

5887

Description:

YBR276C PPS1 SGDID:S000000480, Chr II from 760043-757620, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein phosphatase with specificity for serine, threonine, and tyrosine residues; has a role in the DNA synthesis phase of the cell cycle"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q6AXW7	204	DUS18_RAT Dual specificity protein phosphatas...	73	0.0000007	54.3	38	56	GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
32	P38590	489	MSG5_YEAST Tyrosine-protein phosphatase MSG5 ...	78	0.0000008	56.2	32	56	GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
									GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0071511; P:inactivation of MAPK activity involved in conjugation with cellular fusion; IMP:SGD.::GO:0060237; P:regulation of fungal-type cell wall organization; IMP:SGD.::GO:0071701; P:regulation of MAPK export from nucleus; IMP:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome.
33	Q6IVY4	691	SSH_XENLA Protein phosphatase Slingshot homol...	65	0.000001	55.8	43	62	GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
34	Q5BIP9	188	DUS18_BOVIN Dual specificity protein phosphat...	139	0.000002	52.8	30	46	GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
35	Q8NEJ0	188	DUS18_HUMAN Dual specificity protein phosphat...	132	0.000002	52.4	31	47	GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
36	Q9Y6W6	482	DUS10_HUMAN Dual specificity protein phosphat...	60	0.000002	54.7	43	65	GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
									GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0043508; P:negative regulation of JUN kinase activity; IBA:RefGenome.
37	Q0IID7	482	DUS10_BOVIN Dual specificity protein phosphat...	60	0.000002	54.7	43	65	GO:0005634; C:nucleus; IBA:RefGenome.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
									GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0043508; P:negative regulation of JUN kinase activity; IBA:RefGenome.
38	Q9ESS0	483	DUS10_MOUSE Dual specificity protein phosphat...	60	0.000002	54.7	43	65	GO:0005634; C:nucleus; IBA:RefGenome.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
									GO:0046329; P:negative regulation of JNK cascade; IMP:MGI.::GO:0043508; P:negative regulation of JUN kinase activity; IMP:MGI.::GO:0060266; P:negative regulation of respiratory burst involved in inflammatory response; IMP:MGI.::GO:0002819; P:regulation of adaptive immune response; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.
39	Q5R8X2	188	DUS18_PONAB Dual specificity protein phosphat...	132	0.000002	52.4	32	46	GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
40	Q8K330	649	SSH3_MOUSE Protein phosphatase Slingshot homo...	65	0.000002	55.1	42	60	GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
									GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
41	Q8WUJ0	223	STYX_HUMAN Serine/threonine/tyrosine-interact...	112	0.000005	52	32	45	GO:0005737; C:cytoplasm; IBA:RefGenome.
									GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
									GO:0007283; P:spermatogenesis; IBA:RefGenome.
42	Q5RDP3	223	STYX_PONAB Serine/threonine/tyrosine-interact...	112	0.000005	52	32	45
									GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
43	Q60969	223	STYX_MOUSE Serine/threonine/tyrosine-interact...	112	0.000005	52	32	45
									GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
44	Q6B8I0	188	MDSP_MOUSE Dual specificity protein phosphata...	85	0.000005	51.2	42	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:MGI.
45	Q63340	280	DUS7_RAT Dual specificity protein phosphatase...	74	0.000007	52	35	57	GO:0005829; C:cytosol; IDA:RGD.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.
46	Q39491	276	PTP3_CHLMO Dual specificity protein phosphata...	104	0.000008	52	33	46
									GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.
47	Q16828	381	DUS6_HUMAN Dual specificity protein phosphata...	101	0.000009	52.4	33	52	GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
									GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.::GO:0051409; P:response to nitrosative stress; IEP:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
48	Q2KJ36	381	DUS6_BOVIN Dual specificity protein phosphata...	101	0.00001	52.4	33	52	GO:0005829; C:cytosol; IBA:RefGenome.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
									GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.
49	Q5U593	223	STYXB_XENLA Serine/threonine/tyrosine-interac...	125	0.00001	50.8	30	44
									GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
50	Q64346	381	DUS6_RAT Dual specificity protein phosphatase...	101	0.00001	52	33	52	GO:0005829; C:cytosol; IBA:RefGenome.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
									GO:0030154; P:cell differentiation; IEP:RGD.::GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:RGD.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.::GO:0042493; P:response to drug; IEP:RGD.::GO:0070848; P:response to growth factor stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.
51	Q9DBB1	381	DUS6_MOUSE Dual specificity protein phosphata...	101	0.00001	52	33	52	GO:0005829; C:cytosol; IBA:RefGenome.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
									GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IMP:MGI.
52	Q4V7N3	223	STYXA_XENLA Serine/threonine/tyrosine-interac...	125	0.00001	50.8	30	44
									GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
53	Q8TE77	659	SSH3_HUMAN Protein phosphatase Slingshot homo...	65	0.00001	52.4	42	55	GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
									GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
54	Q5XIS1	652	SSH3_RAT Protein phosphatase Slingshot homolo...	65	0.00001	52.4	40	58	GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
									GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
55	Q91Z46	422	DUS7_MOUSE Dual specificity protein phosphata...	74	0.00001	52	35	57	GO:0005829; C:cytosol; IBA:RefGenome.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
56	Q9VVW5	411	DUSK3_DROME Dual specificity protein phosphat...	98	0.00001	52	34	48	GO:0005829; C:cytosol; IBA:RefGenome.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
									GO:0016337; P:cell-cell adhesion; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0035160; P:maintenance of epithelial integrity, open tracheal system; IMP:FlyBase.::GO:0002385; P:mucosal immune response; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; IMP:FlyBase.::GO:0042127; P:regulation of cell proliferation; IGI:FlyBase.
57	Q16829	419	DUS7_HUMAN Dual specificity protein phosphata...	74	0.00002	52	35	57	GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
									GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
58	Q54Y32	856	MPL3_DICDI MAP kinase phosphatase with leucin...	57	0.091	40	35	63
									GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
59	P43078	597	PTPX_CANAW Probable tyrosine-protein phosphat...	91	0.00002	52	34	51
									GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
60	Q76I79	1042	SSH1_MOUSE Protein phosphatase Slingshot homo...	94	0.00002	52	34	52	GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
									GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
									GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
61	O13453	278	PMP1_SCHPO Tyrosine-protein phosphatase pmp1 ...	76	0.00002	50.8	33	66	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
									GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; ISS:RefGenome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000165; P:MAPK cascade; NAS:PomBase.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:PomBase.

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