rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
991 | Q6IP06 | 493 | STK3_XENLA Serine/threonine-protein kinase 3 ... | 271 | 3e-17 | 88.2 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB. | 992 | Q99759 | 626 | M3K3_HUMAN Mitogen-activated protein kinase k... | 219 | 3e-17 | 88.6 | 30 | 50 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI. | 993 | P35426 | 303 | CDK4_RAT Cyclin-dependent kinase 4 OS=Rattus ... | 205 | 3e-17 | 86.3 | 34 | 50 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:RGD.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:RGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0045787; P:positive regulation of cell cycle; TAS:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0045793; P:positive regulation of cell size; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0010288; P:response to lead ion; IMP:RGD.::GO:0033574; P:response to testosterone stimulus; IDA:RGD.::GO:0009636; P:response to toxin; IEP:RGD. | 994 | Q62673 | 603 | PLK1_RAT Serine/threonine-protein kinase PLK1... | 187 | 3e-17 | 88.6 | 30 | 58 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0051233; C:spindle midzone; IDA:RGD.::GO:0000922; C:spindle pole; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0000236; P:mitotic prometaphase; IMP:RGD.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0040038; P:polar body extrusion after meiotic divisions; IMP:RGD.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB.::GO:0046677; P:response to antibiotic; IEP:RGD. | 995 | Q6CFS5 | 588 | CBK1_YARLI Serine/threonine-protein kinase CB... | 264 | 3e-17 | 88.6 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 996 | O75676 | 772 | KS6A4_HUMAN Ribosomal protein S6 kinase alpha... | 182 | 6e-17 | 87.8 | 34 | 54 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0048273; F:mitogen-activated protein kinase p38 binding; IGI:UniProtKB.::GO:0004711; F:ribosomal protein S6 kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0043987; P:histone H3-S10 phosphorylation; IMP:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; IMP:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0001818; P:negative regulation of cytokine production; TAS:UniProtKB.::GO:0032793; P:positive regulation of CREB transcription factor activity; TAS:UniProtKB.::GO:0035066; P:positive regulation of histone acetylation; IMP:BHF-UCL.::GO:0033129; P:positive regulation of histone phosphorylation; IMP:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL. | 997 | P18653 | 724 | KS6A1_MOUSE Ribosomal protein S6 kinase alpha... | 201 | 2e-16 | 86.7 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:2000491; P:positive regulation of hepatic stellate cell activation; ISS:UniProtKB. | 998 | A2AAJ9 | 8891 | OBSCN_MOUSE Obscurin OS=Mus musculus (Mouse).... | 224 | 0.000000000006 | 72.8 | 28 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 999 | Q5VST9 | 7968 | OBSCN_HUMAN Obscurin OS=Homo sapiens (Human).... | 215 | 0.00000000004 | 70.1 | 26 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; ISS:BHF-UCL.::GO:0030018; C:Z disc; ISS:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0008307; F:structural constituent of muscle; NAS:BHF-UCL.::GO:0031432; F:titin binding; IPI:BHF-UCL. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 1000 | Q9V3I5 | 1207 | JIL1_DROME Chromosomal serine/threonine-prote... | 289 | 0.0000000002 | 67.4 | 27 | 42 | GO:0000228; C:nuclear chromosome; IDA:UniProtKB.::GO:0005705; C:polytene chromosome interband; IDA:UniProtKB.::GO:0016456; C:X chromosome located dosage compensation complex, transcription activating; IPI:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0031936; P:negative regulation of chromatin silencing; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |