Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR274W
Length:
527
Number of sequences:
5887
Description:
YBR274W CHK1 SGDID:S000000478, Chr II from 749594-751177, Genome Release 64-1-1, Verified ORF, "Serine/threonine kinase and DNA damage checkpoint effector, mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331P07934    388   PHKG1_MOUSE Phosphorylase b kinase gamma cata...2619e-27     115     29     48GO:0005964; C:phosphorylase kinase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
332Q66JF3    417   MKNK1_XENTR MAP kinase-interacting serine/thr...2859e-27     115     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
333Q9JLM8    756   DCLK1_MOUSE Serine/threonine-protein kinase D...3051e-26     118     31     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0048675; P:axon extension; IGI:MGI.::GO:0021952; P:central nervous system projection neuron axonogenesis; IGI:MGI.::GO:0048813; P:dendrite morphogenesis; IGI:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0001764; P:neuron migration; IGI:MGI.
334P0CY24    1228   STE20_CANAL Serine/threonine-protein kinase C...2021e-26     118     35     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0001410; P:chlamydospore formation; IMP:CGD.::GO:0000747; P:conjugation with cellular fusion; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0000165; P:MAPK cascade; IGI:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0001558; P:regulation of cell growth; IGI:CGD.
335Q61XD3    302   AIR2_CAEBR Aurora/IPL1-related protein kinase...2761e-26     113     28     50GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
336Q9BXA7    367   TSSK1_HUMAN Testis-specific serine/threonine-...2871e-26     114     29     52GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0019861; C:flagellum; ISS:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007286; P:spermatid development; ISS:UniProtKB.
337P0CY23    1230   STE20_CANAX Serine/threonine-protein kinase C...2021e-26     118     35     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
338C4YRB7    1224   STE20_CANAW Serine/threonine-protein kinase C...2021e-26     118     35     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
339O94168    619   SNF1_CANTR Carbon catabolite-derepressing pro...2811e-26     117     32     55GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
340Q6RET6    527   CCAMK_PEA Calcium and calcium/calmodulin-depe...2661e-26     116     29     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0009877; P:nodulation; IEA:UniProtKB-KW.
341A5A7I8    535   CDPK5_SOLTU Calcium-dependent protein kinase ...3101e-26     117     30     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
342B3M6I4    770   PLK4_DROAN Serine/threonine-protein kinase PL...2881e-26     117     31     55GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
343P53681    602   CRK_DAUCA CDPK-related protein kinase OS=Dauc...2701e-26     117     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
344Q9QYZ6    504   SMK2A_MOUSE Sperm motility kinase 2A OS=Mus m...2781e-26     116     30     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
345Q38870    646   CDPK2_ARATH Calcium-dependent protein kinase ...2741e-26     117     31     49GO:0005789; C:endoplasmic reticulum membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
346P53684    542   CDPKB_ORYSJ Calcium-dependent protein kinase ...3011e-26     116     30     51GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
347P23647    805   FUSED_DROME Serine/threonine-protein kinase f...2671e-26     117     33     54GO:0035301; C:Hedgehog signaling complex; IPI:FlyBase.::GO:0016020; C:membrane; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase.
GO:0007293; P:germarium-derived egg chamber formation; IMP:FlyBase.::GO:0007228; P:positive regulation of hh target transcription factor activity; IMP:FlyBase.::GO:0042993; P:positive regulation of transcription factor import into nucleus; IMP:FlyBase.::GO:0031647; P:regulation of protein stability; IDA:FlyBase.::GO:0030162; P:regulation of proteolysis; NAS:FlyBase.::GO:0007367; P:segment polarity determination; IMP:FlyBase.
348Q55FT4    2247   TSUA_DICDI Probable serine/threonine-protein ...2761e-26     118     33     51GO:0005881; C:cytoplasmic microtubule; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; IMP:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase.
349P53355    1430   DAPK1_HUMAN Death-associated protein kinase 1...2762e-26     117     32     54GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
GO:0006915; P:apoptotic process; IGI:MGI.::GO:0008624; P:induction of apoptosis by extracellular signals; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:UniProtKB.
350Q6NLQ6    538   CDPKW_ARATH Calcium-dependent protein kinase ...2712e-26     116     30     48GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
351Q9WTK7    436   STK11_MOUSE Serine/threonine-protein kinase S...2832e-26     115     29     52GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0030275; F:LRR domain binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0030295; F:protein kinase activator activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IMP:UniProtKB.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:MGI.::GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; IMP:UniProtKB.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0051645; P:Golgi localization; IMP:MGI.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0060770; P:negative regulation of epithelial cell proliferation involved in prostate gland development; IMP:MGI.::GO:0050772; P:positive regulation of axonogenesis; IGI:MGI.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051896; P:regulation of protein kinase B signaling cascade; IMP:MGI.::GO:0030111; P:regulation of Wnt receptor signaling pathway; IMP:MGI.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0007286; P:spermatid development; IMP:UniProtKB.::GO:0001894; P:tissue homeostasis; IMP:MGI.::GO:0001944; P:vasculature development; IMP:UniProtKB.
352Q00771    414   KCC1_EMENI Calcium/calmodulin-dependent prote...3042e-26     114     31     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
353Q69ZM6    1316   STK36_MOUSE Serine/threonine-protein kinase 3...2722e-26     117     32     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.
GO:0042384; P:cilium assembly; IDA:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; IDA:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:UniProtKB.
354Q6AVM3    516   CCAMK_ORYSJ Calcium and calcium/calmodulin-de...3212e-26     115     27     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
355B4GXC2    755   DCLK_DROPE Serine/threonine-protein kinase GL...2862e-26     117     34     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
356P00518    387   PHKG1_RABIT Phosphorylase b kinase gamma cata...2592e-26     114     29     46GO:0005964; C:phosphorylase kinase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
357P06782    633   SNF1_YEAST Carbon catabolite-derepressing pro...2742e-26     116     31     55GO:0031588; C:AMP-activated protein kinase complex; IDA:SGD.::GO:0000324; C:fungal-type vacuole; IPI:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005641; C:nuclear envelope lumen; IDA:SGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0004679; F:AMP-activated protein kinase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0042710; P:biofilm formation; IMP:SGD.::GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IMP:SGD.::GO:0006995; P:cellular response to nitrogen starvation; IDA:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0017148; P:negative regulation of translation; IMP:SGD.::GO:0045722; P:positive regulation of gluconeogenesis; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0007165; P:signal transduction; TAS:SGD.
358Q00372    612   SNF1_CANGA Carbon catabolite-derepressing pro...2782e-26     116     32     54GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
359O60285    661   NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS...2692e-26     116     30     55GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:2000772; P:regulation of cellular senescence; IDA:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; IDA:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
360Q8SWM6    488   CDC5_ENCCU Probable cell cycle serine/threoni...2822e-26     115     27     54GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
361B5DK35    755   DCLK_DROPS Serine/threonine-protein kinase GA...2863e-26     116     34     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
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