Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR274W
Length:
527
Number of sequences:
5887
Description:
YBR274W CHK1 SGDID:S000000478, Chr II from 749594-751177, Genome Release 64-1-1, Verified ORF, "Serine/threonine kinase and DNA damage checkpoint effector, mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271Q9ZV15    583   CDPKK_ARATH Calcium-dependent protein kinase ...2826e-28     121     30     50GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
272Q9C6P3    521   CDPKX_ARATH Calcium-dependent protein kinase ...2346e-28     120     32     50GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
273Q42479    529   CDPK3_ARATH Calcium-dependent protein kinase ...2726e-28     120     32     49GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0010359; P:regulation of anion channel activity; IMP:TAIR.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.
274A8WYE4    1088   PAR1_CAEBR Serine/threonine-protein kinase pa...2827e-28     122     30     52GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
275Q9ZSA4    485   CDPKR_ARATH Calcium-dependent protein kinase ...2827e-28     119     30     51GO:0005829; C:cytosol; IDA:TAIR.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
276Q39192    362   SRK2D_ARATH Serine/threonine-protein kinase S...2718e-28     117     30     52GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009789; P:positive regulation of abscisic acid mediated signaling pathway; IGI:TAIR.::GO:0010029; P:regulation of seed germination; IGI:TAIR.::GO:0009739; P:response to gibberellin stimulus; IGI:TAIR.::GO:0009651; P:response to salt stress; IDA:TAIR.
277Q8C0X8    640   SMKX_MOUSE Sperm motility kinase X OS=Mus mus...2108e-28     120     37     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
278Q9N0X0    344   AURKB_PIG Aurora kinase B OS=Sus scrofa (Pig)...2739e-28     117     32     53GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
279Q6DEH3    491   KC2D1_DANRE Calcium/calmodulin-dependent prot...2789e-28     119     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
280P22987    891   KIN1_SCHPO Protein kinase kin1 OS=Schizosacch...3139e-28     121     30     50GO:0032153; C:cell division site; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0015630; C:microtubule cytoskeleton; TAS:PomBase.::GO:0035839; C:non-growing cell tip; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0060632; P:regulation of microtubule-based movement; IMP:PomBase.::GO:0010687; P:site selection involved in cell cycle cytokinesis; IMP:PomBase.
281B4QK53    769   PLK4_DROSI Serine/threonine-protein kinase PL...2789e-28     121     31     55GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
282Q9NJU9    562   CDPK3_PLAF7 Calcium-dependent protein kinase ...2131e-27     120     31     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
283Q9TW45    1192   PAR1_CAEEL Serine/threonine-protein kinase pa...2821e-27     121     30     52GO:0005938; C:cell cortex; IDA:WormBase.::GO:0016020; C:membrane; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase.
GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009880; P:embryonic pattern specification; IMP:WormBase.::GO:0030010; P:establishment of cell polarity; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0009949; P:polarity specification of anterior/posterior axis; TAS:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
284B4IAQ8    769   PLK4_DROSE Serine/threonine-protein kinase PL...2781e-27     121     31     55GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
285O97143    769   PLK4_DROME Serine/threonine-protein kinase PL...2781e-27     121     31     55GO:0005814; C:centriole; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0046599; P:regulation of centriole replication; IDA:FlyBase.::GO:0007288; P:sperm axoneme assembly; IMP:FlyBase.
286Q3MHJ9    542   KCC2B_BOVIN Calcium/calmodulin-dependent prot...2781e-27     120     29     51GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
287A5A7I7    557   CDPK4_SOLTU Calcium-dependent protein kinase ...3141e-27     120     30     50GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
288Q9M101    520   CDPKN_ARATH Calcium-dependent protein kinase ...2311e-27     119     32     51GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0046686; P:response to cadmium ion; IEP:TAIR.
289Q13554    666   KCC2B_HUMAN Calcium/calmodulin-dependent prot...2781e-27     120     30     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051924; P:regulation of calcium ion transport; TAS:UniProtKB.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:UniProtKB.::GO:0014733; P:regulation of skeletal muscle adaptation; TAS:UniProtKB.::GO:0051823; P:regulation of synapse structural plasticity; TAS:UniProtKB.
290Q6C3J2    371   IPL1_YARLI Spindle assembly checkpoint kinase...2781e-27     117     32     49GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
291Q06850    610   CDPK1_ARATH Calcium-dependent protein kinase ...2781e-27     120     31     47GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.
292Q96PF2    358   TSSK2_HUMAN Testis-specific serine/threonine-...2741e-27     117     29     55GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0007286; P:spermatid development; ISS:UniProtKB.
293B4J3F1    762   PLK4_DROGR Serine/threonine-protein kinase PL...2712e-27     120     30     55GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
294Q2LYK3    777   PLK4_DROPS Serine/threonine-protein kinase PL...2872e-27     120     32     54GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
295B4HBU3    777   PLK4_DROPE Serine/threonine-protein kinase PL...2872e-27     120     32     54GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
296Q8W4I7    528   CDPKD_ARATH Calcium-dependent protein kinase ...2812e-27     119     32     50GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.
297Q9UQB9    309   AURKC_HUMAN Aurora kinase C OS=Homo sapiens (...2732e-27     115     31     53GO:0032133; C:chromosome passenger complex; TAS:UniProtKB.::GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000793; C:condensed chromosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB.
GO:0008608; P:attachment of spindle microtubules to kinetochore; TAS:UniProtKB.::GO:0000910; P:cytokinesis; TAS:ProtInc.::GO:0016570; P:histone modification; TAS:UniProtKB.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; TAS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; TAS:UniProtKB.
298Q2TA06    402   AURKA_BOVIN Aurora kinase A OS=Bos taurus (Bo...2822e-27     117     30     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
299Q02723    502   RKIN1_SECCE Carbon catabolite-derepressing pr...2782e-27     119     31     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
300Q9U1Y5    476   CHK2_CAEEL Serine/threonine-protein kinase ch...2792e-27     118     30     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
301B7XHR6    595   KIN1_ENTBH Probable serine/threonine-protein ...2082e-27     119     38     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
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