Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR265W
Length:
320
Number of sequences:
5887
Description:
YBR265W TSC10 SGDID:S000000469, Chr II from 738582-739544, Genome Release 64-1-1, Verified ORF, "3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis, essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine, member of short chain dehydrogenase/reductase protein family"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38342    320   TSC10_YEAST 3-ketodihydrosphingosine reductas...3200     668     100     100GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016651; F:oxidoreductase activity, acting on NADH or NADPH; IDA:SGD.
GO:0006666; P:3-keto-sphinganine metabolic process; IDA:SGD.::GO:0030148; P:sphingolipid biosynthetic process; IDA:SGD.
2Q6FQ42    363   TSC10_CANGA 3-ketodihydrosphingosine reductas...3615e-100     305     44     61GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
3Q758B6    307   TSC10_ASHGO 3-ketodihydrosphingosine reductas...3128e-90     277     47     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
4Q6CLN0    313   TSC10_KLULA 3-ketodihydrosphingosine reductas...3234e-88     273     45     61GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
5Q6BQK1    328   TSC10_DEBHA 3-ketodihydrosphingosine reductas...3074e-60     201     39     55GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
6Q59RQ2    271   TSC10_CANAL 3-ketodihydrosphingosine reductas...2865e-54     184     38     58GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
7Q6CE86    372   TSC10_YARLI 3-ketodihydrosphingosine reductas...3191e-35     137     31     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
8Q5BE65    369   TSC10_EMENI 3-ketodihydrosphingosine reductas...3281e-26     112     30     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
9Q9Y7P2    503   YCKF_SCHPO Uncharacterized protein C1450.15 O...2982e-21     97.8     27     45GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016651; F:oxidoreductase activity, acting on NADH or NADPH; ISS:PomBase.::GO:0000234; F:phosphoethanolamine N-methyltransferase activity; ISS:PomBase.
GO:0006666; P:3-keto-sphinganine metabolic process; ISS:PomBase.::GO:0006506; P:GPI anchor biosynthetic process; ISS:PomBase.
10Q556J2    334   KDSR_DICDI 3-ketodihydrosphingosine reductase...2837e-18     85.9     26     43GO:0042406; C:extrinsic to endoplasmic reticulum membrane; ISS:dictyBase.
GO:0047560; F:3-dehydrosphinganine reductase activity; ISS:dictyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0030148; P:sphingolipid biosynthetic process; ISS:dictyBase.
11Q7RZR2    325   TSC10_NEUCR 3-ketodihydrosphingosine reductas...3392e-17     84.3     26     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
12P0CR36    335   TSC10_CRYNJ 3-ketodihydrosphingosine reductas...2482e-17     84.3     30     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
13P0CR37    335   TSC10_CRYNB 3-ketodihydrosphingosine reductas...2254e-17     84     31     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
14Q06136    332   KDSR_HUMAN 3-ketodihydrosphingosine reductase...3120.00000000000002     75.9     26     43GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006666; P:3-keto-sphinganine metabolic process; IDA:MGI.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
15Q2KIJ5    331   KDSR_BOVIN 3-ketodihydrosphingosine reductase...3110.0000000000008     71.6     25     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
16Q6GV12    332   KDSR_MOUSE 3-ketodihydrosphingosine reductase...3060.00000000003     66.6     25     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0030148; P:sphingolipid biosynthetic process; IGI:MGI.
17Q8U8I2    249   SDH_AGRT5 Serine 3-dehydrogenase OS=Agrobacte...2110.000002     52     25     42
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031132; F:serine 3-dehydrogenase activity; IEA:EC.
18P25145    248   Y432_LISMO Uncharacterized oxidoreductase Lmo...2200.000002     52     25     41
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
19Q92EK7    248   Y452_LISIN Uncharacterized oxidoreductase Lin...2200.000002     51.6     24     41
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
20Q5HLD8    230   Y2049_STAEQ Uncharacterized oxidoreductase SE...2170.000006     50.1     23     45
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
21Q8CN40    230   Y2036_STAES Uncharacterized oxidoreductase SE...2170.000006     50.1     23     45
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
22Q9KWN1    249   SDH_RHIRD Serine 3-dehydrogenase OS=radiobact...2100.00001     49.7     25     40
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031132; F:serine 3-dehydrogenase activity; IEA:EC.
23Q4A054    234   Y0419_STAS1 Uncharacterized oxidoreductase SS...2240.00004     47.8     21     39
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
24Q8T197    316   DHRS7_DICDI Dehydrogenase/reductase SDR famil...2090.00006     47.8     24     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
25Q6Q7D2    287   DHI1L_MACFA Hydroxysteroid 11-beta-dehydrogen...1960.00007     47.4     25     42GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
26P25970    253   Y5909_MYXXD Uncharacterized oxidoreductase MX...1040.00009     47     26     46
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
27Q0VFE7    309   DRS7B_XENTR Dehydrogenase/reductase SDR famil...2170.0002     46.2     25     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
28Q7Z5J1    315   DHI1L_HUMAN Hydroxysteroid 11-beta-dehydrogen...1960.0002     45.8     24     41GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
29P39577    252   DLTE_BACSU Uncharacterized oxidoreductase dlt...2100.0002     45.4     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
30Q49WS9    246   Y1627_STAS1 Uncharacterized oxidoreductase SS...2180.0003     45.4     24     44
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
31Q2FVD5    231   Y2778_STAA8 Uncharacterized oxidoreductase SA...2170.0003     45.1     21     41
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
records
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