Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR264C
Length:
199
Number of sequences:
5887
Description:
YBR264C YPT10 SGDID:S000000468, Chr II from 738369-737770, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTP-binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
781P08644    189   RASK_RAT GTPase KRas OS=Rattus norvegicus (Ra...1440.000002     49.7     26     47GO:0045121; C:membrane raft; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0019003; F:GDP binding; IDA:RGD.::GO:0019002; F:GMP binding; IDA:RGD.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0030275; F:LRR domain binding; IDA:RGD.
GO:0019221; P:cytokine-mediated signaling pathway; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:RGD.::GO:0051000; P:positive regulation of nitric-oxide synthase activity; IMP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0051385; P:response to mineralocorticoid stimulus; IEP:RGD.::GO:0035176; P:social behavior; IEP:RGD.
782P32883    189   RASK_MOUSE GTPase KRas OS=Mus musculus (Mouse...1440.000002     49.7     26     47GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IGI:MGI.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.::GO:0035022; P:positive regulation of Rac protein signal transduction; IGI:MGI.::GO:0007265; P:Ras protein signal transduction; IGI:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IGI:MGI.::GO:0032228; P:regulation of synaptic transmission, GABAergic; IGI:MGI.::GO:0051146; P:striated muscle cell differentiation; IGI:MGI.::GO:0008542; P:visual learning; IGI:MGI.
783Q5S007    2527   LRRK2_HUMAN Leucine-rich repeat serine/threon...1250.000002     51.2     25     52GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL.
GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL.
784P01116    189   RASK_HUMAN GTPase KRas OS=Homo sapiens (Human...1410.000002     49.7     26     45GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0000165; P:MAPK cascade; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
785P08642    189   RASH_CHICK GTPase HRas OS=Gallus gallus (Chic...1860.000002     49.7     25     43GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
786Q75A26    181   ARF_ASHGO ADP-ribosylation factor OS=Y-1056) ...1340.000002     49.3     25     49GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
787Q4PB75    752   GEM1_USTMA Mitochondrial Rho GTPase 1 OS=Usti...1370.000002     50.4     29     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
788Q6GPS4    235   RABL3_XENLA Rab-like protein 3 OS=Xenopus lae...1390.000003     49.7     28     45
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
789P01120    322   RAS2_YEAST Ras-like protein 2 OS=Saccharomyce...1480.000003     50.1     29     49GO:0005886; C:plasma membrane; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0005525; F:GTP binding; IDA:SGD.::GO:0003924; F:GTPase activity; TAS:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007190; P:activation of adenylate cyclase activity; TAS:SGD.::GO:0030437; P:ascospore formation; IMP:SGD.::GO:0000411; P:positive regulation of transcription by galactose; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007265; P:Ras protein signal transduction; TAS:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.
790Q5REU3    201   ARL4D_PONAB ADP-ribosylation factor-like prot...1240.000004     48.9     33     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
791P49703    201   ARL4D_HUMAN ADP-ribosylation factor-like prot...1240.000004     48.9     33     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0009306; P:protein secretion; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
792P04388    192   RAS2_DROME Ras-like protein 2 OS=Drosophila m...2050.000004     48.9     29     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
793P10301    218   RRAS_HUMAN Ras-related protein R-Ras OS=Homo ...1450.000005     48.9     28     44GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0019003; F:GDP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome.
794Q32LJ6    236   RABL3_BOVIN Rab-like protein 3 OS=Bos taurus ...1260.000005     48.9     28     47
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
795Q96D21    266   RHES_HUMAN GTP-binding protein Rhes OS=Homo s...1840.000005     49.3     26     45GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0031681; F:G-protein beta-subunit binding; IPI:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0043949; P:regulation of cAMP-mediated signaling; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IC:UniProtKB.
796Q9BYZ6    727   RHBT2_HUMAN Rho-related BTB domain-containing...1330.000005     49.7     28     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
797Q91V93    728   RHBT2_MOUSE Rho-related BTB domain-containing...1330.000005     49.7     28     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
798Q0VC18    200   ARL4D_BOVIN ADP-ribosylation factor-like prot...1240.000005     48.5     33     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
799P0CM16    182   ARF_CRYNJ ADP-ribosylation factor OS=ATCC MYA...1420.000006     48.1     25     49GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
800P0CM17    182   ARF_CRYNB ADP-ribosylation factor OS=(Filobas...1420.000006     48.1     25     49GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
801Q5ZKR4    230   RABL3_CHICK Rab-like protein 3 OS=Gallus gall...1390.000006     48.9     28     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
802Q55CB8    213   RASX_DICDI Ras-like protein rasX OS=Dictyoste...1580.000007     48.5     25     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:dictyBase.::GO:0003924; F:GTPase activity; ISS:dictyBase.
GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.
803P34727    183   ARF_AJECA ADP-ribosylation factor OS=capsulat...1420.000008     47.8     25     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
804P05774    183   RAS_CARAU Ras-like protein OS=Carassius aurat...1240.00001     47.8     25     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
805P61751    180   ARF4_RAT ADP-ribosylation factor 4 OS=Rattus ...1420.00001     47.4     27     47GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007420; P:brain development; IEP:RGD.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
806P61750    180   ARF4_MOUSE ADP-ribosylation factor 4 OS=Mus m...1420.00001     47.4     27     47GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005525; F:GTP binding; TAS:MGI.
GO:0015031; P:protein transport; TAS:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
807P0CO78    686   GEM1_CRYNJ Mitochondrial Rho GTPase 1 OS=ATCC...1230.00001     48.5     28     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
808P0CO79    686   GEM1_CRYNB Mitochondrial Rho GTPase 1 OS=(Fil...1230.00001     48.5     28     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
809Q7RVM2    185   ARF_NEUCR ADP-ribosylation factor OS=1257 / F...1340.00001     47.4     25     50GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
810B4KB60    181   RAS1_DROMO Ras-like protein 1 OS=Drosophila m...1000.00001     47.4     32     51GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
811Q567Y6    187   RABL5_DANRE Rab-like protein 5 OS=Danio rerio...1290.00001     47.4     26     48
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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