UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR252W

Length:

147

Number of sequences:

5887

Description:

YBR252W DUT1 SGDID:S000000456, Chr II from 722611-723054, Genome Release 64-1-1, Verified ORF, "deoxyuridine triphosphate diphosphatase (dUTPase); catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability; also has diphosphatase activity on deoxyinosine triphosphate"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P33317	147	DUT_YEAST Deoxyuridine 5'-triphosphate nucleo...	147	5e-101	293	100	100	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0035870; F:dITP diphosphatase activity; IDA:SGD.::GO:0004170; F:dUTP diphosphatase activity; IMP:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0035863; P:dITP catabolic process; IDA:SGD.::GO:0046081; P:dUTP catabolic process; IDA:SGD.
2	Q6CQN7	148	DUT_KLULA Deoxyuridine 5'-triphosphate nucleo...	147	5e-78	234	80	86
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
3	Q74ZF0	153	DUT_ASHGO Deoxyuridine 5'-triphosphate nucleo...	143	3e-72	220	79	91
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
4	Q6FKQ6	144	DUT_CANGA Deoxyuridine 5'-triphosphate nucleo...	143	6e-72	219	81	88
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
5	C4YFC7	159	DUT_CANAW Deoxyuridine 5'-triphosphate nucleo...	144	3e-63	197	65	82
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
6	P0CY19	159	DUT_CANAL Deoxyuridine 5'-triphosphate nucleo...	144	3e-63	197	65	82
									GO:0004170; F:dUTP diphosphatase activity; IDA:CGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
7	Q6BRN7	160	DUT_DEBHA Deoxyuridine 5'-triphosphate nucleo...	147	4e-63	197	64	82
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
8	Q6C141	157	DUT_YARLI Deoxyuridine 5'-triphosphate nucleo...	139	9e-54	173	60	76
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
9	Q9P6Q5	140	DUT_SCHPO Probable deoxyuridine 5'-triphospha...	136	2e-51	166	59	77	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0004170; F:dUTP diphosphatase activity; ISS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.::GO:0009213; P:pyrimidine deoxyribonucleoside triphosphate catabolic process; ISS:PomBase.
10	Q10FF9	171	DUT_ORYSJ Deoxyuridine 5'-triphosphate nucleo...	139	3e-48	159	53	75
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
11	Q9STG6	166	DUT_ARATH Deoxyuridine 5'-triphosphate nucleo...	138	1e-47	157	56	72	GO:0005829; C:cytosol; IDA:TAIR.
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
									GO:0006281; P:DNA repair; IMP:TAIR.::GO:0046080; P:dUTP metabolic process; IEA:InterPro.
12	Q6MVL2	165	DUT_NEUCR Deoxyuridine 5'-triphosphate nucleo...	134	1e-47	157	64	75
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
13	P70583	205	DUT_RAT Deoxyuridine 5'-triphosphate nucleoti...	145	2e-47	158	54	69	GO:0005829; C:cytosol; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.
									GO:0004170; F:dUTP diphosphatase activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042975; F:peroxisome proliferator activated receptor binding; IPI:RGD.::GO:0032556; F:pyrimidine deoxyribonucleotide binding; IDA:RGD.::GO:0030547; F:receptor inhibitor activity; IDA:RGD.
									GO:0006226; P:dUMP biosynthetic process; IDA:RGD.::GO:0046081; P:dUTP catabolic process; IDA:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0070207; P:protein homotrimerization; IDA:RGD.::GO:0043497; P:regulation of protein heterodimerization activity; IDA:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.
14	Q54BW5	179	DUT_DICDI Deoxyuridine 5'-triphosphate nucleo...	146	3e-46	154	52	68
									GO:0004170; F:dUTP diphosphatase activity; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.::GO:0009213; P:pyrimidine deoxyribonucleoside triphosphate catabolic process; ISS:dictyBase.
15	P33316	252	DUT_HUMAN Deoxyuridine 5'-triphosphate nucleo...	141	2e-45	154	55	70	GO:0005739; C:mitochondrion; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0004170; F:dUTP diphosphatase activity; EXP:Reactome.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006260; P:DNA replication; TAS:ProtInc.::GO:0046080; P:dUTP metabolic process; IEA:InterPro.::GO:0006206; P:pyrimidine base metabolic process; TAS:Reactome.::GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.
16	P32518	169	DUT_SOLLC Deoxyuridine 5'-triphosphate nucleo...	138	7e-45	150	53	72
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
17	O41033	141	DUT_PBCV1 Deoxyuridine 5'-triphosphate nucleo...	121	2e-42	143	60	75
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
18	Q89662	178	DUT_ADEG1 Deoxyuridine 5'-triphosphate nucleo...	149	1e-41	142	51	67
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
19	P14597	159	DUT_ORFN2 Deoxyuridine 5'-triphosphate nucleo...	147	6e-40	137	49	64
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
20	Q9YYS0	163	DUT_ADEG8 Deoxyuridine 5'-triphosphate nucleo...	138	7e-40	137	49	67
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
21	Q6GZR2	164	DUT_FRG3G Putative deoxyuridine 5'-triphospha...	146	1e-37	132	47	66
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
22	Q9J5G5	145	DUT_FOWPN Deoxyuridine 5'-triphosphate nucleo...	135	1e-35	125	49	64
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
23	P87630	147	DUT_CWPXG Deoxyuridine 5'-triphosphate nucleo...	129	3e-34	122	49	67
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
24	P17374	144	DUT_VACCW Deoxyuridine 5'-triphosphate nucleo...	129	1e-33	121	48	67
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
25	P33826	147	DUT_VAR67 Deoxyuridine 5'-triphosphate nucleo...	129	1e-33	121	48	67
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
26	Q6RZR1	147	DUT_RABPU Deoxyuridine 5'-triphosphate nucleo...	129	1e-33	120	48	67
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
27	P68635	147	DUT_VACCP Deoxyuridine 5'-triphosphate nucleo...	129	3e-33	120	48	67
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
28	P68634	147	DUT_VACCC Deoxyuridine 5'-triphosphate nucleo...	129	3e-33	120	48	67
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
29	Q76RE7	147	DUT_VACCA Deoxyuridine 5'-triphosphate nucleo...	129	3e-33	120	48	67
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
30	P32208	142	DUT_SWPVK Deoxyuridine 5'-triphosphate nucleo...	132	2e-32	117	42	63
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.
31	Q775Z7	147	DUT_CAMPS Deoxyuridine 5'-triphosphate nucleo...	129	3e-32	117	47	66
									GO:0004170; F:dUTP diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0046080; P:dUTP metabolic process; IEA:InterPro.

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