UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR246W

Length:

387

Number of sequences:

5887

Description:

YBR246W RRT2 SGDID:S000000450, Chr II from 711591-712754, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; null mutants display a weak carboxypeptidase Y missorting/secretion phenotype"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P38332	387	WDR85_YEAST Diphthamide biosynthesis protein ...	387	0	807	100	100	GO:0005768; C:endosome; IDA:SGD.
									GO:0017178; F:diphthine-ammonia ligase activity; IMP:SGD.
									GO:0032456; P:endocytic recycling; IMP:SGD.::GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IMP:SGD.
2	O74865	310	WDR85_SCHPO WD repeat-containing protein C18....	360	2e-28	117	26	46	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
									GO:0006360; P:transcription from RNA polymerase I promoter; ISS:PomBase.
3	Q55C80	367	WDR85_DICDI WD repeat-containing protein 85 h...	408	0.0000000000002	74.7	24	38
4	Q9BTV6	452	WDR85_HUMAN WD repeat-containing protein 85 O...	178	0.0000000000004	74.3	32	48
									GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IMP:UniProtKB.
5	Q9CYU6	477	WDR85_MOUSE WD repeat-containing protein 85 O...	27	2.4	33.9	59	70
									GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; ISS:UniProtKB.
6	Q39190	479	PRL2_ARATH Protein pleiotropic regulator PRL2...	73	0.056	39.3	40	52	GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.
									GO:0005515; F:protein binding; IPI:TAIR.
7	Q6CU55	439	LIS1_KLULA Nuclear distribution protein PAC1 ...	73	0.067	38.9	29	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
8	Q42384	486	PRL1_ARATH Protein pleiotropic regulatory loc...	73	0.14	37.7	36	52	GO:0080008; C:CUL4 RING ubiquitin ligase complex; IPI:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0048825; P:cotyledon development; IMP:TAIR.::GO:0009870; P:defense response signaling pathway, resistance gene-dependent; IMP:TAIR.::GO:0010204; P:defense response signaling pathway, resistance gene-independent; IMP:TAIR.::GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0050832; P:defense response to fungus; IMP:TAIR.::GO:0009755; P:hormone-mediated signaling pathway; IMP:TAIR.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0048366; P:leaf development; IMP:TAIR.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:TAIR.::GO:0006508; P:proteolysis; IMP:TAIR.::GO:0009749; P:response to glucose stimulus; IMP:TAIR.::GO:0048364; P:root development; IMP:TAIR.::GO:0010182; P:sugar mediated signaling pathway; IMP:TAIR.
9	A7TNS8	669	CAF4_VANPO CCR4-associated factor 4 homolog O...	77	0.17	37.7	38	49	GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
10	Q5ZJW8	720	DTL_CHICK Denticleless protein homolog OS=Gal...	75	0.18	37.7	31	48	GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
11	Q9NZJ0	730	DTL_HUMAN Denticleless protein homolog OS=Hom...	37	0.23	37.4	38	54	GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB.::GO:0019985; P:translesion synthesis; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
12	Q12510	522	YD156_YEAST WD repeat-containing protein YDL1...	127	0.26	37	24	44	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000790; C:nuclear chromatin; IDA:SGD.
									GO:0003677; F:DNA binding; IDA:SGD.
13	Q8SRK1	384	HAT2_ENCCU Histone acetyltransferase type B s...	90	0.36	36.6	32	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
14	O13923	601	CORO_SCHPO Coronin-like protein crn1 OS=Schiz...	181	0.52	36.2	23	38	GO:0030479; C:actin cortical patch; IDA:PomBase.::GO:0005826; C:actomyosin contractile ring; IDA:PomBase.::GO:0005885; C:Arp2/3 protein complex; ISS:RefGenome.::GO:0051286; C:cell tip; IDA:PomBase.
									GO:0051015; F:actin filament binding; ISS:RefGenome.
									GO:0051666; P:actin cortical patch localization; ISS:RefGenome.::GO:0051017; P:actin filament bundle assembly; TAS:PomBase.::GO:0030041; P:actin filament polymerization; NAS:PomBase.::GO:0034316; P:negative regulation of Arp2/3 complex-mediated actin nucleation; ISS:RefGenome.
15	P0CS49	473	PRP46_CRYNB Pre-mRNA-splicing factor PRP46 OS...	99	0.58	35.8	30	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
16	Q6BU94	417	PRP46_DEBHA Pre-mRNA-splicing factor PRP46 OS...	74	0.59	35.8	35	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
17	P0CS48	473	PRP46_CRYNJ Pre-mRNA-splicing factor PRP46 OS...	99	0.6	35.8	30	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
18	A7TL17	536	YD156_VANPO WD repeat-containing protein Kpol...	80	0.66	35.8	29	46
19	Q4V837	710	DTLA_XENLA Denticleless protein homolog A OS=...	73	1	35.4	29	49	GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
20	A3DM49	203	PYRE_STAMF Orotate phosphoribosyltransferase ...	84	1.2	34.3	29	46
									GO:0004588; F:orotate phosphoribosyltransferase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
21	Q6P1W0	713	DTL_XENTR Denticleless protein homolog OS=Xen...	73	1.2	35	30	48	GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
22	Q7MYJ5	616	ILVD_PHOLL Dihydroxy-acid dehydratase OS=Phot...	130	1.8	34.3	26	41
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004160; F:dihydroxy-acid dehydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
23	A0PPN8	935	CAPP_MYCUA Phosphoenolpyruvate carboxylase OS...	95	2	34.3	27	54
									GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:EC.
									GO:0015977; P:carbon fixation; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
24	Q4WT34	453	PRP46_ASPFU Pre-mRNA-splicing factor prp46 OS...	75	2.1	34.3	32	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
25	A6ZQL5	714	MDV1_YEAS7 Mitochondrial division protein 1 O...	90	2.4	33.9	29	44	GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
26	Q329V0	616	ILVD_SHIDS Dihydroxy-acid dehydratase OS=Shig...	130	2.5	33.9	24	42
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004160; F:dihydroxy-acid dehydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
27	P39108	375	PEX7_YEAST Peroxisomal targeting signal 2 rec...	175	2.5	33.9	23	42	GO:0005829; C:cytosol; IDA:SGD.::GO:0005777; C:peroxisome; IDA:SGD.
									GO:0005053; F:peroxisome matrix targeting signal-2 binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0016560; P:protein import into peroxisome matrix, docking; IPI:SGD.
28	B5YY20	616	ILVD_ECO5E Dihydroxy-acid dehydratase OS=Esch...	130	2.6	33.9	24	42
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004160; F:dihydroxy-acid dehydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
29	Q8XAV1	616	ILVD_ECO57 Dihydroxy-acid dehydratase OS=Esch...	130	2.6	33.9	24	42
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004160; F:dihydroxy-acid dehydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
30	P47025	714	MDV1_YEAST Mitochondrial division protein 1 O...	90	2.6	33.9	29	44	GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
									GO:0043130; F:ubiquitin binding; IDA:SGD.
									GO:0000266; P:mitochondrial fission; IMP:SGD.::GO:0000002; P:mitochondrial genome maintenance; IMP:SGD.
31	Q7MGI8	613	ILVD_VIBVY Dihydroxy-acid dehydratase OS=Vibr...	130	2.9	33.9	25	42
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004160; F:dihydroxy-acid dehydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.

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