UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR237W

Length:

849

Number of sequences:

5887

Description:

YBR237W PRP5 SGDID:S000000441, Chr II from 691969-694518, Genome Release 64-1-1, Verified ORF, "RNA helicase in the DEAD-box family, necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q84UQ1	1049	RH42_ORYSJ DEAD-box ATP-dependent RNA helicas...	99	0.0000002	58.5	36	58
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
32	Q8H0U8	1166	RH42_ARATH DEAD-box ATP-dependent RNA helicas...	108	0.000000002	65.5	40	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
33	Q4TVV3	1018	DDX46_DANRE Probable ATP-dependent RNA helica...	80	0.000002	55.1	36	56	GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
34	Q62780	1032	DDX46_RAT Probable ATP-dependent RNA helicase...	80	0.000002	55.5	36	56	GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
35	Q569Z5	1032	DDX46_MOUSE Probable ATP-dependent RNA helica...	80	0.000002	55.5	36	56	GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
36	Q7L014	1031	DDX46_HUMAN Probable ATP-dependent RNA helica...	80	0.000002	55.1	36	56	GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
37	Q5R6D8	1032	DDX46_PONAB Probable ATP-dependent RNA helica...	80	0.000002	55.1	36	56	GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
38	Q9SF41	989	RH45_ARATH DEAD-box ATP-dependent RNA helicas...	96	0.00000001	62.4	38	50
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
39	Q553B1	1151	DDX46_DICDI ATP-dependent RNA helicase ddx46 ...	70	4.2	34.7	40	53	GO:0005681; C:spliceosomal complex; ISS:dictyBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:dictyBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; ISS:dictyBase.::GO:0000375; P:RNA splicing, via transesterification reactions; ISS:dictyBase.
40	Q0UN57	1184	PRP5_PHANO Pre-mRNA-processing ATP-dependent ...	88	0.00000000003	71.2	41	57	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
41	Q0J7Y8	947	RH45_ORYSJ DEAD-box ATP-dependent RNA helicas...	60	0.00008	50.1	47	57
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
42	Q9C718	501	RH20_ARATH DEAD-box ATP-dependent RNA helicas...	420	8e-94	310	40	60	GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
43	Q5N7W4	666	RH30_ORYSJ DEAD-box ATP-dependent RNA helicas...	477	2e-91	309	40	57	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
44	P0CQ76	540	DBP2_CRYNJ ATP-dependent RNA helicase DBP2-A ...	465	4e-91	304	39	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
45	P0CQ77	540	DBP2_CRYNB ATP-dependent RNA helicase DBP2-A ...	465	4e-91	304	39	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
46	P24782	550	DBP2_SCHPO ATP-dependent RNA helicase dbp2 OS...	470	3e-90	302	39	56	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.
									GO:0005524; F:ATP binding; ISS:PomBase.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; ISS:PomBase.::GO:0006364; P:rRNA processing; ISS:PomBase.
47	Q8W4R3	591	RH30_ARATH DEAD-box ATP-dependent RNA helicas...	434	2e-89	301	40	57	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
48	Q4PHU9	552	DBP2_USTMA ATP-dependent RNA helicase DBP2 OS...	420	4e-89	299	40	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
49	Q5QMN3	494	RH20_ORYSJ DEAD-box ATP-dependent RNA helicas...	420	7e-89	296	40	59	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
50	Q6CIV2	554	DBP2_KLULA ATP-dependent RNA helicase DBP2 OS...	449	1e-87	295	38	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
51	A5DL80	554	DBP2_PICGU ATP-dependent RNA helicase DBP2 OS...	440	1e-87	295	40	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
52	Q6FLF3	544	DBP2_CANGA ATP-dependent RNA helicase DBP2 OS...	433	2e-87	294	39	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
53	P17844	614	DDX5_HUMAN Probable ATP-dependent RNA helicas...	450	3e-87	296	37	57	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.
									GO:0050681; F:androgen receptor binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.::GO:0036002; F:pre-mRNA binding; IDA:UniProtKB.::GO:0003724; F:RNA helicase activity; IMP:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
									GO:0016049; P:cell growth; NAS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IMP:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.::GO:2001014; P:regulation of skeletal muscle cell differentiation; ISS:UniProtKB.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
54	Q4R6M5	614	DDX5_MACFA Probable ATP-dependent RNA helicas...	450	3e-87	296	37	57	GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003724; F:RNA helicase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.::GO:2001014; P:regulation of skeletal muscle cell differentiation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55	Q59LU0	562	DBP2_CANAL ATP-dependent RNA helicase DBP2 OS...	438	3e-87	294	38	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
56	P24783	546	DBP2_YEAST ATP-dependent RNA helicase DBP2 OS...	421	4e-87	293	38	59	GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IPI:SGD.::GO:0006364; P:rRNA processing; IMP:SGD.
57	Q6C4D4	552	DBP2_YARLI ATP-dependent RNA helicase DBP2 OS...	456	4e-87	293	38	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
58	A6ZRX0	546	DBP2_YEAS7 ATP-dependent RNA helicase DBP2 OS...	421	4e-87	293	38	59	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
59	Q10MH8	770	RH24_ORYSJ DEAD-box ATP-dependent RNA helicas...	557	4e-87	299	34	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
60	Q61656	614	DDX5_MOUSE Probable ATP-dependent RNA helicas...	450	8e-87	295	37	57	GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003724; F:RNA helicase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
									GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; IMP:UniProtKB.::GO:2001014; P:regulation of skeletal muscle cell differentiation; IMP:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
61	Q755N4	557	DBP2_ASHGO ATP-dependent RNA helicase DBP2 OS...	424	1e-86	292	38	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.

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