Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR218C
Length:
1180
Number of sequences:
5887
Description:
YBR218C PYC2 SGDID:S000000422, Chr II from 662249-658707, Genome Release 64-1-1, reverse complement, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q09794    2244   PYR1_SCHPO Protein ura1 OS=Schizosaccharomyce...1820.007     44.7     20     40GO:0005829; C:cytosol; IDA:PomBase.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IGI:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IGI:PomBase.::GO:0004151; F:dihydroorotase activity; IGI:PomBase.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IGI:PomBase.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IGI:PomBase.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0000050; P:urea cycle; IC:PomBase.
302B8H8U5    1109   CARB_ARTCA Carbamoyl-phosphate synthase large...1950.000005     54.7     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
303Q4L574    374   PURK_STAHJ N5-carboxyaminoimidazole ribonucle...1900.000001     55.5     24     42
GO:0034028; F:5-(carboxyamino)imidazole ribonucleotide synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; IEA:InterPro.
GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
304P02904    123   BCCP_PROFR Methylmalonyl-CoA carboxyltransfer...640.000002     52.8     39     67
GO:0047154; F:methylmalonyl-CoA carboxytransferase activity; IEA:EC.
305Q91293    1496   CPSM_LITCT Carbamoyl-phosphate synthase [ammo...2920.000002     56.2     22     43GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004087; F:carbamoyl-phosphate synthase (ammonia) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0000050; P:urea cycle; IEA:UniProtKB-KW.
306Q8EYF0    387   PURT_LEPIN Phosphoribosylglycinamide formyltr...2990.000002     55.1     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
307Q72LY0    387   PURT_LEPIC Phosphoribosylglycinamide formyltr...2990.000002     55.1     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
308P59448    1076   CARB_BUCBP Carbamoyl-phosphate synthase large...1950.00002     52.8     22     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
309P39771    384   PURT_BACSU Phosphoribosylglycinamide formyltr...2950.000003     54.7     24     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
310Q8F832    1106   CARB_LEPIN Carbamoyl-phosphate synthase large...3260.00003     52.4     23     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
311Q72NF1    1106   CARB_LEPIC Carbamoyl-phosphate synthase large...3260.00003     52.4     23     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
312O50236    1112   CARB_ZYMMO Carbamoyl-phosphate synthase large...2470.004     45.4     20     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
313Q8TUT7    542   CARB2_METKA Carbamoyl-phosphate synthase larg...1970.000004     54.7     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
314Q91437    2242   PYR1_SQUAC CAD protein OS=Squalus acanthias (...2350.000005     55.1     22     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0004151; F:dihydroorotase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
315Q49WI9    375   PURK_STAS1 N5-carboxyaminoimidazole ribonucle...2350.000005     53.9     22     41
GO:0034028; F:5-(carboxyamino)imidazole ribonucleotide synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; IEA:InterPro.
GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
316P05990    2224   PYR1_DROME CAD protein OS=Drosophila melanoga...2400.000006     54.7     22     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IDA:FlyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IDA:FlyBase.::GO:0004151; F:dihydroorotase activity; IDA:FlyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IMP:FlyBase.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
317Q9A4D6    1099   CARB_CAUCR Carbamoyl-phosphate synthase large...2570.004     45.1     19     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
318Q9ZKT2    1085   CARB_HELPJ Carbamoyl-phosphate synthase large...2240.00005     51.2     23     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
319B2GI87    1106   CARB_KOCRD Carbamoyl-phosphate synthase large...2360.001     47     22     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
320Q9ZAA7    145   GCDC_ACIFV Glutaconyl-CoA decarboxylase subun...660.00001     50.4     38     62
GO:0018801; F:glutaconyl-CoA decarboxylase activity; IEA:EC.
GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
321Q9UZ08    486   LEU1_PYRAB 2-isopropylmalate synthase OS=Pyro...1620.00001     53.1     25     46
GO:0003852; F:2-isopropylmalate synthase activity; IEA:HAMAP.
GO:0009098; P:leucine biosynthetic process; IEA:HAMAP.
322B0REV9    1096   CARB_CLAMS Carbamoyl-phosphate synthase large...2050.00006     51.2     23     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
323B7GPW2    1127   CARB_BIFLS Carbamoyl-phosphate synthase large...1890.003     45.8     22     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
324Q827Q7    1102   CARB_STRAW Carbamoyl-phosphate synthase large...1810.0008     47.4     23     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
325P05115    70   BCCP_SOLLC Biotin carboxyl carrier protein of...550.00001     49.3     49     69GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
326Q8TWX0    564   CARB1_METKA Carbamoyl-phosphate synthase larg...1610.00001     53.1     22     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
327A0B8K9    1074   CARB_METTP Carbamoyl-phosphate synthase large...1900.81     37.7     23     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
328Q8U2A2    499   LEU1_PYRFU 2-isopropylmalate synthase OS=Pyro...1440.00002     52.8     26     47
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
329A8H9A1    523   LEU1_SHEPA 2-isopropylmalate synthase OS=Shew...2940.00002     52.8     23     41
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
330C4LDC0    394   PURT_TOLAT Phosphoribosylglycinamide formyltr...2370.00002     52     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
331B1W463    1102   CARB_STRGG Carbamoyl-phosphate synthase large...1810.0002     49.3     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
records
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