UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR218C

Length:

1180

Number of sequences:

5887

Description:

YBR218C PYC2 SGDID:S000000422, Chr II from 662249-658707, Genome Release 64-1-1, reverse complement, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
271	Q71YI1	1070	CARB_LISMF Carbamoyl-phosphate synthase large...	236	0.0000009	57	22	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
272	Q92AH3	1070	CARB_LISIN Carbamoyl-phosphate synthase large...	236	0.000007	54.3	21	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
273	B8DDR7	1070	CARB_LISMH Carbamoyl-phosphate synthase large...	236	0.0000009	57.4	22	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
274	P38100	1073	CARB_PSEAE Carbamoyl-phosphate synthase large...	246	0.0000003	58.9	24	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
275	Q7U054	1115	CARB_MYCBO Carbamoyl-phosphate synthase large...	193	0.0000007	57.4	26	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
276	Q97AJ3	1044	CARB_THEVO Carbamoyl-phosphate synthase large...	297	0.0000002	58.9	24	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
277	A9WSA8	1106	CARB_RENSM Carbamoyl-phosphate synthase large...	195	0.004	45.1	22	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
278	Q8Y665	1070	CARB_LISMO Carbamoyl-phosphate synthase large...	236	0.000007	54.3	22	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
279	B1YIR9	1070	CARB_EXIS2 Carbamoyl-phosphate synthase large...	237	0.0000009	57.4	22	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
280	O67869	557	CARB1_AQUAE Carbamoyl-phosphate synthase larg...	293	0.0000003	58.2	25	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
281	Q8TYM1	509	CIMA_METKA Putative (R)-citramalate synthase ...	124	0.0000003	58.2	32	47
									GO:0043714; F:(R)-citramalate synthase activity; IEA:InterPro.::GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
282	P57689	1115	CARB_MYCTU Carbamoyl-phosphate synthase large...	193	0.0000007	57.4	26	43	GO:0005886; C:plasma membrane; IDA:MTBBASE.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
283	B9DRV7	1058	CARB_STRU0 Carbamoyl-phosphate synthase large...	216	0.000004	55.1	22	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
284	Q8TNY4	1070	CARB_METAC Carbamoyl-phosphate synthase large...	244	0.058	41.6	21	39
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
285	Q8TW28	397	AKSA_METKA Putative homocitrate synthase AksA...	129	0.0000004	57.4	29	45
									GO:0004410; F:homocitrate synthase activity; IEA:EC.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
286	Q9JXW8	1071	CARB_NEIMB Carbamoyl-phosphate synthase large...	238	0.00005	51.6	22	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
287	B8DTW3	1136	CARB_BIFA0 Carbamoyl-phosphate synthase large...	240	0.001	47	22	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
288	Q07WG9	522	LEU1_SHEFN 2-isopropylmalate synthase OS=Shew...	294	0.0000004	57.8	25	41
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
289	Q58595	518	LEU1_METJA 2-isopropylmalate synthase OS=JCM ...	101	0.0000005	57.4	34	50
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
290	Q9JW02	1071	CARB_NEIMA Carbamoyl-phosphate synthase large...	238	0.00002	52.8	22	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
291	A1R6Z3	1102	CARB_ARTAT Carbamoyl-phosphate synthase large...	195	0.00003	52	23	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
292	A0JX72	1099	CARB_ARTS2 Carbamoyl-phosphate synthase large...	195	0.00004	51.6	23	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
293	O25577	1085	CARB_HELPY Carbamoyl-phosphate synthase large...	269	0.00003	52.4	21	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
294	C1F1S6	1093	CARB_ACIC5 Carbamoyl-phosphate synthase large...	245	0.000003	55.5	24	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
295	Q8TYB1	499	LEU1_METKA Probable 2-isopropylmalate synthas...	275	0.0000009	56.6	24	39
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
296	P27708	2225	PYR1_HUMAN CAD protein OS=Homo sapiens (Human...	194	4.8	35	19	38	GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; ISS:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0043195; C:terminal button; ISS:BHF-UCL.
									GO:0070335; F:aspartate binding; ISS:BHF-UCL.::GO:0004070; F:aspartate carbamoyltransferase activity; ISS:BHF-UCL.::GO:0005524; F:ATP binding; ISS:BHF-UCL.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; ISS:BHF-UCL.::GO:0004151; F:dihydroorotase activity; ISS:BHF-UCL.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0042802; F:identical protein binding; ISS:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; ISS:BHF-UCL.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; ISS:BHF-UCL.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0017144; P:drug metabolic process; ISS:BHF-UCL.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; ISS:BHF-UCL.::GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
297	P08955	2225	PYR1_MESAU CAD protein OS=Mesocricetus auratu...	194	0.87	37.7	20	38	GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005739; C:mitochondrion; IDA:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL.
									GO:0070335; F:aspartate binding; IDA:BHF-UCL.::GO:0004070; F:aspartate carbamoyltransferase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IDA:BHF-UCL.::GO:0004151; F:dihydroorotase activity; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IDA:BHF-UCL.::GO:0002134; F:UTP binding; IDA:MGI.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IDA:BHF-UCL.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
298	Q7M8I0	387	PURT_WOLSU Phosphoribosylglycinamide formyltr...	297	0.000001	55.8	23	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
299	A1SRG8	519	LEU1_PSYIN 2-isopropylmalate synthase OS=Psyc...	257	0.000001	56.2	24	40
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
300	Q9PIL7	1089	CARB_CAMJE Carbamoyl-phosphate synthase large...	259	0.00001	53.1	22	37
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
301	Q09794	2244	PYR1_SCHPO Protein ura1 OS=Schizosaccharomyce...	182	0.007	44.7	20	40	GO:0005829; C:cytosol; IDA:PomBase.
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IGI:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IGI:PomBase.::GO:0004151; F:dihydroorotase activity; IGI:PomBase.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IGI:PomBase.::GO:0046872; F:metal ion binding; IEA:InterPro.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IGI:PomBase.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0000050; P:urea cycle; IC:PomBase.

records

Previous

‹‹

››

Next

Total records:

979

271 - 300