UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR218C

Length:

1180

Number of sequences:

5887

Description:

YBR218C PYC2 SGDID:S000000422, Chr II from 662249-658707, Genome Release 64-1-1, reverse complement, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
241	P58942	1080	CARB_XANAC Carbamoyl-phosphate synthase large...	273	0.00002	52.8	25	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
242	Q58773	482	CARB1_METJA Carbamoyl-phosphate synthase larg...	235	0.00000002	61.6	24	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
243	Q8XHB3	1067	CARB_CLOPE Carbamoyl-phosphate synthase large...	349	0.0000001	60.1	21	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
244	Q0TM79	1067	CARB_CLOP1 Carbamoyl-phosphate synthase large...	349	0.0000001	60.1	21	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
245	Q8CPP2	375	PURK_STAES N5-carboxyaminoimidazole ribonucle...	215	0.00000003	61.2	24	44
									GO:0034028; F:5-(carboxyamino)imidazole ribonucleotide synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; IEA:InterPro.
									GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
246	Q469Z7	1071	CARB_METBF Carbamoyl-phosphate synthase large...	246	0.00006	51.2	24	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
247	C1CXR4	1029	CARB_DEIDV Carbamoyl-phosphate synthase large...	232	0.002	46.2	22	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
248	O93937	2275	PYR1_EMENI Protein pyrABCN OS=194 / M139) (As...	187	0.004	45.4	20	39
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; TAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; TAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:InterPro.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; TAS:UniProtKB.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
249	B1HQC1	1065	CARB_LYSSC Carbamoyl-phosphate synthase large...	236	0.000001	57	24	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
250	A6LPD9	1069	CARB_CLOB8 Carbamoyl-phosphate synthase large...	339	0.00000004	61.6	21	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
251	Q1D6Y8	1083	CARB_MYXXD Carbamoyl-phosphate synthase large...	238	0.000002	56.2	24	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
252	Q9CCR2	1121	CARB_MYCLE Carbamoyl-phosphate synthase large...	193	0.00001	53.1	24	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
253	Q55756	1081	CARB_SYNY3 Carbamoyl-phosphate synthase large...	203	0.005	45.1	21	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
254	Q8YQL2	1104	CARB_NOSS1 Carbamoyl-phosphate synthase large...	180	0.0003	48.9	24	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
255	Q8XZ83	1081	CARB_RALSO Carbamoyl-phosphate synthase large...	243	0.00003	52.4	22	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
256	P58944	1073	CARB_METMA Carbamoyl-phosphate synthase large...	283	0.00007	50.8	23	39
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
257	B0KBW4	1072	CARB_THEP3 Carbamoyl-phosphate synthase large...	238	0.00001	53.9	22	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
258	O94313	1160	CARB_SCHPO Carbamoyl-phosphate synthase argin...	130	0.13	40.4	22	45	GO:0005951; C:carbamoyl-phosphate synthase complex; ISS:PomBase.::GO:0005739; C:mitochondrion; IDA:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; ISS:PomBase.::GO:0000050; P:urea cycle; IC:PomBase.
259	Q7VP67	1075	CARB_HAEDU Carbamoyl-phosphate synthase large...	284	0.00006	51.2	22	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
260	Q834E2	1060	CARB_ENTFA Carbamoyl-phosphate synthase large...	233	0.0000001	60.1	26	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
261	O28994	1076	CARB_ARCFU Carbamoyl-phosphate synthase large...	310	0.000002	55.8	22	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
262	A8F453	1105	CARB_THELT Carbamoyl-phosphate synthase large...	270	0.049	41.6	21	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
263	O67233	537	CARB2_AQUAE Carbamoyl-phosphate synthase larg...	229	0.0000001	59.3	22	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
264	A0AJU0	1070	CARB_LISW6 Carbamoyl-phosphate synthase large...	236	0.0000009	57	22	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
265	P46056	1176	CARB_TRICU Carbamoyl-phosphate synthase argin...	141	0.14	40	26	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.
266	C1A4I5	1094	CARB_GEMAT Carbamoyl-phosphate synthase large...	195	0.000004	55.1	26	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
267	Q1B9F9	1112	CARB_MYCSS Carbamoyl-phosphate synthase large...	250	0.0003	48.9	22	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
268	A1UFK4	1112	CARB_MYCSK Carbamoyl-phosphate synthase large...	250	0.0003	48.9	22	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
269	A3PZ65	1112	CARB_MYCSJ Carbamoyl-phosphate synthase large...	250	0.0003	48.9	22	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
270	C1KWD4	1070	CARB_LISMC Carbamoyl-phosphate synthase large...	236	0.0000006	57.8	22	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
271	Q71YI1	1070	CARB_LISMF Carbamoyl-phosphate synthase large...	236	0.0000009	57	22	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.

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