Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR218C
Length:
1180
Number of sequences:
5887
Description:
YBR218C PYC2 SGDID:S000000422, Chr II from 662249-658707, Genome Release 64-1-1, reverse complement, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32327    1180   PYC2_YEAST Pyruvate carboxylase 2 OS=Saccharo...11800     2443     100     100GO:0005829; C:cytosol; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IMP:SGD.
GO:0006094; P:gluconeogenesis; IMP:SGD.
2P11154    1178   PYC1_YEAST Pyruvate carboxylase 1 OS=Saccharo...11700     2250     93     98GO:0005829; C:cytosol; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004736; F:pyruvate carboxylase activity; IMP:SGD.
GO:0006094; P:gluconeogenesis; IMP:SGD.
3Q8X1T3    1175   PYC_PICAN Pyruvate carboxylase OS=Pichia angu...11610     1859     77     88GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
4P78992    1189   PYC_PICPA Pyruvate carboxylase OS=Pichia past...11600     1812     76     87GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
5Q9HES8    1192   PYC_ASPNG Pyruvate carboxylase OS=Aspergillus...11580     1679     71     84GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
6O93918    1193   PYC_ASPTE Pyruvate carboxylase OS=Aspergillus...11580     1677     71     84GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
7Q0CLK1    1193   PYC_ASPTN Pyruvate carboxylase OS=Aspergillus...11580     1672     71     84GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
8Q9UUE1    1185   PYC_SCHPO Pyruvate carboxylase OS=Schizosacch...11740     1577     65     80GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; ISS:PomBase.
GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0006094; P:gluconeogenesis; ISS:PomBase.
9O17732    1175   PYC1_CAEEL Pyruvate carboxylase 1 OS=Caenorha...11570     1279     55     73GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
10P11498    1178   PYC_HUMAN Pyruvate carboxylase, mitochondrial...11540     1230     54     70GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0009374; F:biotin binding; TAS:ProtInc.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; TAS:Reactome.
GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.
11Q29RK2    1178   PYC_BOVIN Pyruvate carboxylase, mitochondrial...11540     1228     54     71GO:0005743; C:mitochondrial inner membrane; ISS:AgBase.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.
12P52873    1178   PYC_RAT Pyruvate carboxylase, mitochondrial O...11540     1221     54     71GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0009374; F:biotin binding; IMP:RGD.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IDA:RGD.
GO:0006094; P:gluconeogenesis; IDA:RGD.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.::GO:0006107; P:oxaloacetate metabolic process; IDA:RGD.::GO:0006090; P:pyruvate metabolic process; IDA:RGD.
13Q05920    1178   PYC_MOUSE Pyruvate carboxylase, mitochondrial...11540     1217     53     71GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.
14Q9KWU4    1148   PYC_BACSU Pyruvate carboxylase OS=Bacillus su...11560     1133     49     67
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:InterPro.
15Q58626    501   PYCA_METJA Pyruvate carboxylase subunit A OS=...4501e-131     418     47     68
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
16O30019    506   PYCA_ARCFU Pyruvate carboxylase subunit A OS=...4697e-126     402     47     65
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
17O27939    491   PYCA_METTH Pyruvate carboxylase subunit A OS=...4488e-126     402     46     65
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
18Q06862    447   ACCC_NOSS1 Biotin carboxylase OS=Nostoc sp. (...4484e-125     399     46     63
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
19P49787    450   ACCC1_BACSU Biotin carboxylase 1 OS=Bacillus ...4476e-122     390     46     66
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
20Q9KDS9    452   ACCC_BACHD Biotin carboxylase OS=9153 / C-125...4525e-121     388     46     65
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
21D3DJ42    472   2OCS_HYDTT 2-oxoglutarate carboxylase small s...4608e-117     377     44     64
GO:0034029; F:2-oxoglutarate carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.
22B9HBA8    528   ACCC1_POPTR Biotin carboxylase 1, chloroplast...4456e-112     366     44     61
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
23O04983    537   ACCC_ARATH Biotin carboxylase, chloroplastic ...4467e-112     366     44     61GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0003989; F:acetyl-CoA carboxylase activity; IDA:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IDA:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IDA:TAIR.
24P37798    449   ACCC_PSEAE Biotin carboxylase OS=12228). GN=a...4472e-110     359     44     64
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
25B9N843    526   ACCC2_POPTR Biotin carboxylase 2, chloroplast...4452e-110     362     44     61
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
26P43873    448   ACCC_HAEIN Biotin carboxylase OS=Haemophilus ...4398e-110     357     47     64
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
27O34544    444   ACCC2_BACSU Biotin carboxylase 2 OS=Bacillus ...4465e-108     352     44     61
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
28Q96RQ3    725   MCCA_HUMAN Methylcrotonoyl-CoA carboxylase su...670.00000008     60.5     48     60GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.::GO:0005759; C:mitochondrial matrix; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009374; F:biotin binding; NAS:UniProtKB.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; NAS:UniProtKB.
GO:0006768; P:biotin metabolic process; NAS:UniProtKB.::GO:0006552; P:leucine catabolic process; NAS:UniProtKB.
29Q91ZA3    724   PCCA_MOUSE Propionyl-CoA carboxylase alpha ch...670.000008     53.9     42     64GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; IMP:MGI.
30Q5I0C3    715   MCCA_RAT Methylcrotonoyl-CoA carboxylase subu...690.0000006     57.4     42     59GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IEA:EC.
31Q54KE6    699   MCCA_DICDI Methylcrotonoyl-CoA carboxylase su...640.0001     49.7     41     61GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; ISS:dictyBase.
GO:0006552; P:leucine catabolic process; ISS:dictyBase.
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