UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR213W

Length:

274

Number of sequences:

5887

Description:

YBR213W MET8 SGDID:S000000417, Chr II from 650368-651192, Genome Release 64-1-1, Verified ORF, "Bifunctional dehydrogenase and ferrochelatase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P15807	274	MET8_YEAST Siroheme biosynthesis protein MET8...	274	0	565	100	100
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IDA:SGD.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.
									GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IMP:SGD.::GO:0000103; P:sulfate assimilation; IMP:SGD.
2	O14172	264	MET8_SCHPO Siroheme biosynthesis protein met8...	248	3e-23	100	30	48	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; ISS:PomBase.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.
									GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; ISS:PomBase.::GO:0000103; P:sulfate assimilation; ISS:PomBase.
3	A7MJ67	471	CYSG1_CROS8 Siroheme synthase 1 OS=Cronobacte...	191	0.000000006	59.7	27	47
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
4	Q1QAX7	523	CYSG_PSYCK Siroheme synthase OS=Psychrobacter...	194	0.0000005	53.9	28	43
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
5	O34813	162	SIRC_BACSU Precorrin-2 dehydrogenase OS=Bacil...	201	0.000002	50.4	24	42
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
6	Q2KWB0	461	CYSG_BORA1 Siroheme synthase OS=Bordetella av...	216	0.000002	52	25	41
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
7	Q4FSU1	549	CYSG_PSYA2 Siroheme synthase OS=Psychrobacter...	194	0.000004	51.2	28	42
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
8	B8GUD3	489	CYSG_THISH Siroheme synthase OS=Thioalkalivib...	178	0.000006	50.8	25	42
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
9	Q3JCS0	468	CYSG_NITOC Siroheme synthase OS=Nitrosococcus...	179	0.00001	49.7	24	44
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
10	Q1H3L5	467	CYSG_METFK Siroheme synthase OS=Methylobacill...	186	0.00002	49.3	24	41
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
11	A6TD45	471	CYSG1_KLEP7 Siroheme synthase 1 OS=78578). GN...	191	0.00003	48.5	23	43
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
12	B3GZA0	486	CYSG_ACTP7 Siroheme synthase OS=Actinobacillu...	188	0.00004	48.1	24	45
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
13	Q48H75	464	CYSG_PSE14 Siroheme synthase OS=Pseudomonas s...	198	0.00005	48.1	25	40
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
14	Q7N8L2	470	CYSG_PHOLL Siroheme synthase OS=Photorhabdus ...	186	0.00005	47.8	25	44
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
15	Q5NRM4	471	CYSG_ZYMMO Siroheme synthase OS=Zymomonas mob...	225	0.00006	47.8	24	43
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
16	B7UW11	465	CYSG_PSEA8 Siroheme synthase OS=Pseudomonas a...	197	0.00006	47.8	24	40
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
17	Q02NA3	465	CYSG_PSEAB Siroheme synthase OS=Pseudomonas a...	197	0.00006	47.8	24	40
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
18	Q9I0M7	465	CYSG_PSEAE Siroheme synthase OS=12228). GN=cy...	197	0.00006	47.4	24	40
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
19	A4XUX3	462	CYSG_PSEMY Siroheme synthase OS=Pseudomonas m...	181	0.00006	47.4	27	40
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
20	A4SRH0	480	CYSG2_AERS4 Siroheme synthase 2 OS=Aeromonas ...	169	0.00007	47.4	25	43
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
21	A6V4H6	465	CYSG_PSEA7 Siroheme synthase OS=Pseudomonas a...	197	0.00009	47	24	40
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
22	C3JY53	464	CYSG_PSEFS Siroheme synthase OS=Pseudomonas f...	196	0.0001	46.6	27	40
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
23	A0KP37	470	CYSG2_AERHH Siroheme synthase 2 OS=Aeromonas ...	164	0.0002	46.2	26	41
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
24	Q4K9V8	464	CYSG_PSEF5 Siroheme synthase OS=Pseudomonas f...	198	0.0002	45.8	25	41
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
25	A0KLD7	463	CYSG1_AERHH Siroheme synthase 1 OS=Aeromonas ...	220	0.0002	45.8	25	41
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
26	A5WEG6	487	CYSG_PSYWF Siroheme synthase OS=Psychrobacter...	186	0.0003	45.4	25	41
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
27	A4VLU6	465	CYSG_PSEU5 Siroheme synthase OS=Pseudomonas s...	194	0.0003	45.4	24	39
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
28	A9LZ77	480	CYSG_NEIM0 Siroheme synthase OS=Neisseria men...	183	0.0004	45.1	21	45
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
29	B0BTC2	486	CYSG_ACTPJ Siroheme synthase OS=Actinobacillu...	188	0.0005	44.7	22	44
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
30	Q0A812	481	CYSG_ALHEH Siroheme synthase OS=Alkalilimnico...	214	0.0005	44.7	22	41
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
31	P57500	473	CYSG_BUCAI Siroheme synthase OS=(Acyrthosipho...	185	0.001	43.5	25	45
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.

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