Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR201W
Length:
211
Number of sequences:
5887
Description:
YBR201W DER1 SGDID:S000000405, Chr II from 623576-624211, Genome Release 64-1-1, Verified ORF, "Endoplasmic reticulum membrane protein, required for ER-associated protein degradation of misfolded or unassembled proteins; N- and C- termini protrude into the cytoplasm, has similarity to Dfm1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38307    211   DER1_YEAST Degradation in the endoplasmic ret...2112e-153     431     100     100GO:0000839; C:Hrd1p ubiquitin ligase ERAD-L complex; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008233; F:peptidase activity; IMP:UniProtKB.
GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
2Q54NN1    254   DERL2_DICDI Probable derlin-2 homolog OS=Dict...1990.0000001     53.9     26     46GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:dictyBase.
GO:0030433; P:ER-associated protein catabolic process; ISS:dictyBase.::GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
3Q21997    237   DERL2_CAEEL Derlin-2 OS=Caenorhabditis elegan...2000.000002     50.1     25     49GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0030970; P:retrograde protein transport, ER to cytosol; ISS:UniProtKB.
4Q9D8K3    228   DERL3_MOUSE Derlin-3 OS=Mus musculus (Mouse)....1810.00003     47     24     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
5Q8BNI4    239   DERL2_MOUSE Derlin-2 OS=Mus musculus (Mouse)....1930.00006     46.2     22     45GO:0005769; C:early endosome; IDA:MGI.::GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005770; C:late endosome; IDA:MGI.
GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0030970; P:retrograde protein transport, ER to cytosol; ISS:UniProtKB.
6Q5RC74    239   DERL2_PONAB Derlin-2 OS=Pongo abelii (Sumatra...1930.00009     45.4     21     45GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0030970; P:retrograde protein transport, ER to cytosol; ISS:UniProtKB.
7Q9GZP9    239   DERL2_HUMAN Derlin-2 OS=Homo sapiens (Human)....1930.00009     45.4     21     45GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0030970; P:retrograde protein transport, ER to cytosol; IMP:UniProtKB.
8Q96Q80    235   DERL3_HUMAN Derlin-3 OS=Homo sapiens (Human)....1950.0002     44.7     25     45GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; NAS:UniProtKB.
9Q0P5E4    231   DERL3_BOVIN Derlin-3 OS=Bos taurus (Bovine). ...1850.0003     44.3     24     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
10Q4G2J5    243   DER12_MAIZE Derlin-1.2 OS=Zea mays (Maize). G...1950.007     40     24     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
11Q4G2J6    243   DER11_MAIZE Derlin-1.1 OS=Zea mays (Maize). G...1950.008     40     24     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
12Q9Y7Y0    224   YGR8_SCHPO Uncharacterized derlin-like protei...1020.015     38.9     30     52GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase.
13Q06397    242   DERL1_ORYSJ Derlin-1 OS=Oryza sativa subsp. j...1940.026     38.1     22     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
14Q4G2J4    249   DER21_MAIZE Derlin-2.1 OS=Zea mays (Maize). G...2020.028     38.1     19     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
15Q851X7    249   DERL2_ORYSJ Derlin-2 OS=Oryza sativa subsp. j...2020.037     37.7     19     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
16Q4G2J3    249   DER22_MAIZE Derlin-2.2 OS=Zea mays (Maize). G...2020.039     37.7     19     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
17Q8VZU9    266   DERL1_ARATH Derlin-1 OS=Arabidopsis thaliana ...1970.23     35.4     24     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
18Q93561    245   DERL1_CAEEL Derlin-1 OS=Caenorhabditis elegan...869.3     30.4     27     44GO:0005769; C:early endosome; IDA:WormBase.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0097038; C:perinuclear endoplasmic reticulum; IDA:WormBase.
GO:0006897; P:endocytosis; IMP:WormBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:WormBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0051788; P:response to misfolded protein; IMP:WormBase.
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