rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q498M5 | 735 | SH3R2_RAT Putative E3 ubiquitin-protein ligas... | 57 | 1.4 | 35.4 | 35 | 51 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 182 | Q99K30 | 729 | ES8L2_MOUSE Epidermal growth factor receptor ... | 65 | 1.4 | 35.4 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 183 | Q13625 | 1128 | ASPP2_HUMAN Apoptosis-stimulating of p53 prot... | 64 | 1.5 | 35.4 | 33 | 47 | GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc. | 184 | A7E8B6 | 1150 | SLA1_SCLS1 Actin cytoskeleton-regulatory comp... | 146 | 2.5 | 34.7 | 23 | 38 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 185 | Q84TH9 | 959 | NLP7_ARATH Protein NLP7 OS=Arabidopsis thalia... | 89 | 1.6 | 35.4 | 26 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 186 | Q9DC07 | 270 | LNEBL_MOUSE LIM zinc-binding domain-containin... | 55 | 1.6 | 34.7 | 31 | 51 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 187 | Q14155 | 803 | ARHG7_HUMAN Rho guanine nucleotide exchange f... | 113 | 1.7 | 35.4 | 29 | 50 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043547; P:positive regulation of GTPase activity; IDA:BHF-UCL.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 188 | P20929 | 6669 | NEBU_HUMAN Nebulin OS=Homo sapiens (Human). G... | 97 | 1.7 | 35.4 | 25 | 44 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc. | | | | | | | | | | GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030832; P:regulation of actin filament length; NAS:UniProtKB.::GO:0007525; P:somatic muscle development; NAS:UniProtKB. | 189 | Q6ZQ82 | 814 | RHG26_MOUSE Rho GTPase-activating protein 26 ... | 65 | 1.8 | 35 | 32 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 190 | P63185 | 526 | SRC_RSVSE Tyrosine-protein kinase transformin... | 72 | 1.8 | 35 | 29 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 191 | Q69ZI1 | 892 | SH3R1_MOUSE E3 ubiquitin-protein ligase SH3RF... | 88 | 1.9 | 35 | 27 | 41 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005078; F:MAP-kinase scaffold activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046328; P:regulation of JNK cascade; IDA:MGI. | 192 | P16885 | 1265 | PLCG2_HUMAN 1-phosphatidylinositol 4,5-bispho... | 57 | 1.9 | 35 | 35 | 53 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.::GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; TAS:UniProtKB. | 193 | Q04929 | 305 | CRK_CHICK Adapter molecule crk OS=Gallus gall... | 81 | 2.1 | 34.7 | 27 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 194 | Q8K012 | 605 | FBP1L_MOUSE Formin-binding protein 1-like OS=... | 54 | 2.2 | 34.7 | 33 | 50 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 195 | E7QE10 | 367 | SHO1_YEASZ High osmolarity signaling protein ... | 67 | 2.2 | 34.7 | 31 | 48 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 196 | E7LTJ6 | 367 | SHO1_YEASV High osmolarity signaling protein ... | 67 | 2.2 | 34.7 | 31 | 48 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 197 | E7KMS3 | 367 | SHO1_YEASL High osmolarity signaling protein ... | 67 | 2.2 | 34.7 | 31 | 48 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 198 | E7KBW4 | 367 | SHO1_YEASA High osmolarity signaling protein ... | 67 | 2.2 | 34.7 | 31 | 48 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 199 | B5VHP4 | 367 | SHO1_YEAS6 High osmolarity signaling protein ... | 67 | 2.2 | 34.7 | 31 | 48 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 200 | Q7Z6J0 | 888 | SH3R1_HUMAN E3 ubiquitin-protein ligase SH3RF... | 48 | 2.3 | 35 | 33 | 52 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB. | 201 | A6ZR73 | 367 | SHO1_YEAS7 High osmolarity signaling protein ... | 67 | 2.3 | 34.7 | 31 | 48 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 202 | C7GKW5 | 367 | SHO1_YEAS2 High osmolarity signaling protein ... | 67 | 2.3 | 34.7 | 31 | 48 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 203 | E7Q311 | 367 | SHO1_YEASB High osmolarity signaling protein ... | 67 | 2.3 | 34.7 | 31 | 48 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 204 | Q5RBR0 | 888 | SH3R1_PONAB E3 ubiquitin-protein ligase SH3RF... | 48 | 2.4 | 34.7 | 33 | 52 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 205 | B3LRN4 | 367 | SHO1_YEAS1 High osmolarity signaling protein ... | 67 | 2.4 | 34.7 | 31 | 48 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 206 | P40073 | 367 | SHO1_YEAST High osmolarity signaling protein ... | 67 | 2.5 | 34.3 | 31 | 48 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0044459; C:plasma membrane part; IDA:SGD. | | | | | | | | | | GO:0005078; F:MAP-kinase scaffold activity; IMP:SGD.::GO:0005034; F:osmosensor activity; IPI:SGD. | | | | | | | | | | GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0030010; P:establishment of cell polarity; IGI:SGD.::GO:0007231; P:osmosensory signaling pathway; IPI:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD. | 207 | Q9XVN3 | 769 | IASPP_CAEEL Apoptotic enhancer 1 protein OS=C... | 69 | 2.5 | 34.7 | 35 | 52 | GO:0005634; C:nucleus; ISS:WormBase. | | | | | | | | | | GO:0002039; F:p53 binding; IPI:WormBase. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase. | 208 | Q2HWF0 | 605 | FBP1L_RAT Formin-binding protein 1-like OS=Ra... | 54 | 2.5 | 34.7 | 33 | 50 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW. | 209 | A5D7F8 | 840 | SH3R1_BOVIN E3 ubiquitin-protein ligase SH3RF... | 88 | 2.8 | 34.7 | 28 | 43 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 210 | O76041 | 1014 | NEBL_HUMAN Nebulette OS=Homo sapiens (Human).... | 55 | 2.9 | 34.7 | 31 | 51 | GO:0001725; C:stress fiber; IDA:UniProtKB.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0031005; F:filamin binding; IPI:UniProtKB.::GO:0008307; F:structural constituent of muscle; NAS:UniProtKB.::GO:0005523; F:tropomyosin binding; IPI:UniProtKB. | | | | | | | | | | GO:0071691; P:cardiac muscle thin filament assembly; IMP:UniProtKB. | 211 | P05433 | 440 | GAGC_AVISC P47(GAG-CRK) protein OS=Avian sarc... | 81 | 3.1 | 34.3 | 27 | 52 | GO:0019028; C:viral capsid; IEA:InterPro. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. |