Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR193C
Length:
223
Number of sequences:
5887
Description:
YBR193C MED8 SGDID:S000000397, Chr II from 609753-609082, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38304    223   MED8_YEAST Mediator of RNA polymerase II tran...2235e-163     456     100     100GO:0070847; C:core mediator complex; IDA:SGD.::GO:0016592; C:mediator complex; IEA:InterPro.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IPI:SGD.::GO:0005198; F:structural molecule activity; IMP:SGD.::GO:0017025; F:TBP-class protein binding; IDA:SGD.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
2Q6FJM0    233   MED8_CANGA Mediator of RNA polymerase II tran...2162e-79     244     57     75GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
3Q6CM22    215   MED8_KLULA Mediator of RNA polymerase II tran...2089e-73     226     53     70GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
4Q758L3    223   MED8_ASHGO Mediator of RNA polymerase II tran...1986e-63     202     51     70GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
5Q6CG02    194   MED8_YARLI Mediator of RNA polymerase II tran...2073e-27     108     32     54GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
6Q6BM45    225   MED8_DEBHA Mediator of RNA polymerase II tran...1612e-24     101     37     58GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
7Q59TD3    239   MED8_CANAL Mediator of RNA polymerase II tran...2061e-22     96.7     32     55GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
8O94646    200   MED8_SCHPO Mediator of RNA polymerase II tran...1917e-16     76.6     30     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0016592; C:mediator complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0000920; P:cytokinetic cell separation; IMP:PomBase.
9Q1DLG1    262   MED8_COCIM Mediator of RNA polymerase II tran...1600.0000000000003     70.1     28     49GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
10A1CHE9    254   MED8_ASPCL Mediator of RNA polymerase II tran...1560.000000000003     67     29     51GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
11Q5BCL0    260   MED8_EMENI Mediator of RNA polymerase II tran...1030.000000000006     66.2     35     58GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
12Q4WP83    249   MED8_ASPFU Mediator of RNA polymerase II tran...1540.00000000005     63.5     28     48GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
13Q2UGT1    244   MED8_ASPOR Mediator of RNA polymerase II tran...1490.0000000001     62.8     30     51GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
14A1CXD6    252   MED8_NEOFI Mediator of RNA polymerase II tran...1540.0000000002     62     27     48GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
15A2QID5    269   MED8_ASPNC Mediator of RNA polymerase II tran...1670.000000005     58.2     26     47GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
16Q2HDD6    288   MED8_CHAGB Mediator of RNA polymerase II tran...1660.00000005     55.8     26     44GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
17Q7SGQ0    278   MED8_NEUCR Mediator of RNA polymerase II tran...1050.000006     49.7     28     50GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
18Q8HYW0    697   FA13A_BOVIN Protein FAM13A OS=Bos taurus (Bov...1004.4     32     25     40
19O94988    1023   FA13A_HUMAN Protein FAM13A OS=Homo sapiens (H...1004.9     32     25     40GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
20Q8BGI4    693   FA13A_MOUSE Protein FAM13A OS=Mus musculus (M...1005.7     31.6     24     40
21P27896    566   NARQ_ECOLI Nitrate/nitrite sensor protein nar...555.8     31.6     33     56GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IMP:EcoCyc.
GO:0071249; P:cellular response to nitrate; IMP:EcoCyc.::GO:0071250; P:cellular response to nitrite; IMP:EcoCyc.::GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
22Q8RD98    356   RF1_THETN Peptide chain release factor 1 OS=1...338.5     30.8     39     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016149; F:translation release factor activity, codon specific; IEA:InterPro.
23A1WWV9    383   MNMA_HALHL tRNA-specific 2-thiouridylase MnmA...449.8     30.8     43     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016783; F:sulfurtransferase activity; IEA:InterPro.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
records
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