UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR186W

Length:

564

Number of sequences:

5887

Description:

YBR186W PCH2 SGDID:S000000390, Chr II from 600553-602103,602217-602360, Genome Release 64-1-1, Verified ORF, "Nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in the rDNA"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P38126	564	PCH2_YEAST Pachytene checkpoint protein 2 OS=...	564	0	1149	100	100	GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0040020; P:regulation of meiosis; TAS:SGD.
2	E1C6Q1	432	PCH2_CHICK Pachytene checkpoint protein 2 hom...	322	3e-55	197	36	57
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
3	Q7XK25	471	PCH2_ORYSJ Pachytene checkpoint protein 2 hom...	352	7e-55	197	37	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0007126; P:meiosis; IEA:UniProtKB-KW.
4	A2XUN8	471	PCH2_ORYSI Pachytene checkpoint protein 2 hom...	352	7e-55	197	37	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0007126; P:meiosis; IEA:UniProtKB-KW.
5	Q6P4W8	432	PCH2_XENTR Pachytene checkpoint protein 2 hom...	322	3e-54	195	36	57
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
6	Q8H1F9	467	PCH2_ARATH Pachytene checkpoint protein 2 hom...	324	3e-54	196	37	57
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0007126; P:meiosis; IEA:UniProtKB-KW.
7	Q5XHZ9	432	PCH2_RAT Pachytene checkpoint protein 2 homol...	390	6e-54	194	34	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
8	Q3UA06	432	PCH2_MOUSE Pachytene checkpoint protein 2 hom...	331	2e-53	192	36	57	GO:0001673; C:male germ cell nucleus; IDA:MGI.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:MGI.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0006302; P:double-strand break repair; IMP:UniProtKB.::GO:0007144; P:female meiosis I; IMP:MGI.::GO:0007141; P:male meiosis I; IMP:MGI.::GO:0001556; P:oocyte maturation; IMP:MGI.::GO:0000239; P:pachytene; IMP:MGI.::GO:0007131; P:reciprocal meiotic recombination; IMP:UniProtKB.::GO:0007286; P:spermatid development; IMP:MGI.::GO:0007130; P:synaptonemal complex assembly; IMP:UniProtKB.
9	D3K5L7	431	PCH2_PIG Pachytene checkpoint protein 2 homol...	337	4e-53	192	36	57
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
10	Q15645	432	PCH2_HUMAN Pachytene checkpoint protein 2 hom...	337	8e-53	191	35	57
									GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
									GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
11	E2R222	432	PCH2_CANFA Pachytene checkpoint protein 2 hom...	322	1e-51	188	36	57
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
12	Q6PH52	424	PCH2_DANRE Pachytene checkpoint protein 2 hom...	317	3e-51	187	35	56
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
13	Q09535	424	PCH2_CAEEL Putative pachytene checkpoint prot...	292	2e-41	159	38	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase.
14	C5CBU4	584	ARC_MICLC AAA ATPase forming ring-shaped comp...	173	0.000000000001	74.3	31	50	GO:0000502; C:proteasome complex; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
									GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
15	Q9P7Q4	792	SEC18_SCHPO Vesicular-fusion protein sec18 OS...	191	0.000000000001	74.3	29	51	GO:0005737; C:cytoplasm; IDA:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
									GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0042144; P:vacuole fusion, non-autophagic; ISS:PomBase.
16	Q07590	780	SAV_SULAC Protein SAV OS=NBRC 15157 / NCIMB 1...	183	0.000000000002	73.6	31	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
17	C7R400	550	ARC_JONDD Proteasome-associated ATPase OS=(Li...	173	0.000000000003	72.8	28	51	GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
									GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
18	B3DRN4	521	ARC_BIFLD AAA ATPase forming ring-shaped comp...	167	0.000000000007	71.2	29	52	GO:0000502; C:proteasome complex; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
									GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
19	Q8IYT4	538	KATL2_HUMAN Katanin p60 ATPase-containing sub...	182	0.000000000007	71.6	32	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
20	Q5UQE0	855	YR476_MIMIV Putative AAA family ATPase R476 O...	181	0.000000000009	71.6	29	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
21	Q9HPF0	742	CDCH_HALSA Protein CdcH OS=(Halobacterium hal...	180	0.00000000001	71.2	29	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
22	B7GUP3	521	ARC_BIFLS AAA ATPase forming ring-shaped comp...	167	0.00000000001	70.9	29	52	GO:0000502; C:proteasome complex; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
									GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
23	Q8G3G6	521	ARC_BIFLO AAA ATPase forming ring-shaped comp...	167	0.00000000001	70.5	29	53	GO:0000502; C:proteasome complex; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
									GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
24	B2GIP2	572	ARC_KOCRD AAA ATPase forming ring-shaped comp...	177	0.00000000001	70.9	27	49	GO:0000502; C:proteasome complex; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
									GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
25	Q9D3R6	539	KATL2_MOUSE Katanin p60 ATPase-containing sub...	182	0.00000000001	70.5	31	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
26	P18708	744	NSF_CRIGR Vesicle-fusing ATPase OS=Cricetulus...	182	0.00000000001	70.9	30	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.
27	O28972	733	Y1297_ARCFU Cell division cycle protein 48 ho...	221	0.00000000002	70.5	24	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
28	Q5R410	744	NSF_PONAB Vesicle-fusing ATPase OS=Pongo abel...	182	0.00000000002	70.9	30	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.
29	Q9QUL6	744	NSF_RAT Vesicle-fusing ATPase OS=Rattus norve...	182	0.00000000002	70.9	30	48	GO:0043198; C:dendritic shaft; IDA:UniProtKB.::GO:0005795; C:Golgi stack; IDA:RGD.::GO:0014069; C:postsynaptic density; TAS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0017137; F:Rab GTPase binding; IDA:RGD.
									GO:0007269; P:neurotransmitter secretion; TAS:UniProtKB.::GO:0015031; P:protein transport; IMP:RGD.::GO:0017157; P:regulation of exocytosis; IMP:RGD.::GO:0006906; P:vesicle fusion; TAS:UniProtKB.
30	D3R4I7	524	ARC_BIFAB AAA ATPase forming ring-shaped comp...	221	0.00000000002	70.5	26	48	GO:0000502; C:proteasome complex; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
									GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
31	P46460	744	NSF_MOUSE Vesicle-fusing ATPase OS=Mus muscul...	182	0.00000000002	70.9	30	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; IMP:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019905; F:syntaxin binding; IDA:MGI.
									GO:0006813; P:potassium ion transport; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.

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