Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR183W
Length:
316
Number of sequences:
5887
Description:
YBR183W YPC1 SGDID:S000000387, Chr II from 596115-597065, Genome Release 64-1-1, Verified ORF, "Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity, catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38298    316   YPC1_YEAST Alkaline ceramidase YPC1 OS=Saccha...3160     647     100     100GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0070774; F:phytoceramidase activity; IMP:SGD.::GO:0050291; F:sphingosine N-acyltransferase activity; IMP:SGD.
GO:0046514; P:ceramide catabolic process; IMP:SGD.
2Q02896    317   YDC1_YEAST Alkaline ceramidase YDC1 OS=Saccha...3157e-120     354     53     72GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0071633; F:dihydroceramidase activity; IDA:SGD.
GO:0046514; P:ceramide catabolic process; IMP:SGD.
3Q9D099    267   ACER3_MOUSE Alkaline ceramidase 3 OS=Mus musc...2857e-41     149     33     56
GO:0006672; P:ceramide metabolic process; IEA:InterPro.
4Q9NUN7    267   ACER3_HUMAN Alkaline ceramidase 3 OS=Homo sap...2692e-39     145     35     56GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0030173; C:integral to Golgi membrane; IDA:UniProtKB.
GO:0070774; F:phytoceramidase activity; IDA:UniProtKB.
GO:0006672; P:ceramide metabolic process; IEA:InterPro.::GO:0071602; P:phytosphingosine biosynthetic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0046512; P:sphingosine biosynthetic process; IDA:UniProtKB.
5Q6TMJ1    288   DCD3A_DICDI Putative alkaline ceramidase dcd3...2593e-17     83.2     27     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; ISS:dictyBase.
GO:0046514; P:ceramide catabolic process; ISS:dictyBase.::GO:0006669; P:sphinganine-1-phosphate biosynthetic process; ISS:dictyBase.
6Q55DQ0    285   DCD3B_DICDI Putative alkaline ceramidase dcd3...2601e-16     81.3     30     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; ISS:dictyBase.
GO:0046514; P:ceramide catabolic process; ISS:dictyBase.::GO:0006669; P:sphinganine-1-phosphate biosynthetic process; ISS:dictyBase.
7Q8R4X1    273   ACER1_MOUSE Alkaline ceramidase 1 OS=Mus musc...2530.00000000002     67     22     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; IDA:MGI.
GO:0046514; P:ceramide catabolic process; IDA:MGI.::GO:0019216; P:regulation of lipid metabolic process; IDA:MGI.
8Q8TDN7    264   ACER1_HUMAN Alkaline ceramidase 1 OS=Homo sap...2510.000000002     61.2     23     43GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; IEA:EC.
GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
9Q8VD53    275   ACER2_MOUSE Alkaline ceramidase 2 OS=Mus musc...880.000000003     60.5     39     58
GO:0017040; F:ceramidase activity; IEA:EC.
GO:0006672; P:ceramide metabolic process; IEA:InterPro.
10Q5QJU3    275   ACER2_HUMAN Alkaline ceramidase 2 OS=Homo sap...880.000000005     60.1     39     58GO:0030173; C:integral to Golgi membrane; IDA:UniProtKB.
GO:0017040; F:ceramidase activity; IDA:UniProtKB.
GO:0006672; P:ceramide metabolic process; IEA:InterPro.::GO:0033629; P:negative regulation of cell adhesion mediated by integrin; IDA:UniProtKB.::GO:0001953; P:negative regulation of cell-matrix adhesion; IDA:UniProtKB.::GO:0090285; P:negative regulation of protein glycosylation in Golgi; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0032526; P:response to retinoic acid; IDA:UniProtKB.::GO:0046512; P:sphingosine biosynthetic process; IDA:UniProtKB.
11Q568I2    266   ACER1_DANRE Alkaline ceramidase 1 OS=Danio re...980.0000001     55.8     32     55GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; IEA:EC.
GO:0006672; P:ceramide metabolic process; IEA:InterPro.
12Q9VIP7    283   ACASE_DROME Alkaline ceramidase OS=Drosophila...860.000002     52.4     37     56GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; ISS:UniProtKB.
GO:0007420; P:brain development; IMP:FlyBase.::GO:0046514; P:ceramide catabolic process; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.
13O45145    272   ACASE_CAEEL Alkaline ceramidase OS=Caenorhabd...1030.013     40.4     29     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; IEA:EC.
GO:0006672; P:ceramide metabolic process; IEA:InterPro.
14Q60WT2    272   ACASE_CAEBR Alkaline ceramidase OS=Caenorhabd...1030.031     38.9     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; IEA:EC.
GO:0006672; P:ceramide metabolic process; IEA:InterPro.
15Q8K0H1    567   S47A1_MOUSE Multidrug and toxin extrusion pro...1884.9     32.7     24     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
16Q5I0E9    566   S47A1_RAT Multidrug and toxin extrusion prote...1886.6     32.3     23     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015238; F:drug transmembrane transporter activity; IDA:RGD.::GO:0005451; F:monovalent cation:hydrogen antiporter activity; IMP:RGD.
GO:0015695; P:organic cation transport; IDA:RGD.
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