Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR179C
Length:
855
Number of sequences:
5887
Description:
YBR179C FZO1 SGDID:S000000383, Chr II from 589114-586547, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitofusin; integral membrane protein involved in mitochondrial outer membrane tethering and fusion; role in mitochondrial genome maintenance; efficient tethering and degradation of Fzo1p requires an intact N-terminal GTPase domain; targeted for destruction by the ubiquitin ligase SCF-Mdm30p and the cytosolic ubiquitin-proteasome system"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38297    855   FZO1_YEAST Transmembrane GTPase FZO1 OS=Sacch...8550     1752     100     100GO:0031307; C:integral to mitochondrial outer membrane; IDA:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0042803; F:protein homodimerization activity; IDA:SGD.
GO:0008053; P:mitochondrial fusion; IMP:SGD.
2Q9USY7    758   FZO1_SCHPO Transmembrane GTPase fzo1 OS=Schiz...8193e-104     345     32     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:PomBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:PomBase.
GO:0008053; P:mitochondrial fusion; ISS:PomBase.
3Q7YU24    810   MARF_DROME Transmembrane GTPase Marf OS=Droso...2660.0000005     57.4     24     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0008053; P:mitochondrial fusion; ISS:UniProtKB.
4Q23424    774   FZO1_CAEEL Transmembrane GTPase fzo-1 OS=Caen...1670.000007     53.5     27     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008053; P:mitochondrial fusion; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.
5O18412    718   FZO_DROME Transmembrane GTPase fzo OS=Drosoph...2560.01     43.1     22     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IMP:UniProtKB.
GO:0008053; P:mitochondrial fusion; IMP:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007287; P:Nebenkern assembly; IMP:FlyBase.::GO:0030382; P:sperm mitochondrion organization; IMP:FlyBase.
6P42182    301   ERA_BACSU GTPase Era OS=Bacillus subtilis (st...1180.11     39.3     29     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
7P40983    402   YOR6_CALSR Uncharacterized protein in xynA 3'...2330.13     39.3     22     42
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.
8Q5WHD9    303   ERA_BACSK GTPase Era OS=Bacillus clausii (str...1750.15     38.9     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
9Q892S2    295   ERA_CLOTE GTPase Era OS=Clostridium tetani (s...1760.19     38.5     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
10Q59U11    686   GRC3_CANAL Polynucleotide 5'-hydroxyl-kinase ...490.29     38.5     43     55GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; ISS:UniProtKB.
GO:0006364; P:rRNA processing; ISS:UniProtKB.
11A8MH56    440   DER_ALKOO GTPase Der OS=(strain OhILAs)). GN=...2230.36     38.1     22     39
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
12A3DE77    440   DER_CLOTH GTPase Der OS=Clostridium thermocel...720.45     37.7     36     57
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
13Q8R500    757   MFN2_RAT Mitofusin-2 OS=Rattus norvegicus (Ra...1670.59     37.4     25     45GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031306; C:intrinsic to mitochondrial outer membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IMP:RGD.::GO:0003924; F:GTPase activity; IMP:RGD.::GO:0051020; F:GTPase binding; IPI:UniProtKB.
GO:0008053; P:mitochondrial fusion; IMP:RGD.::GO:0007006; P:mitochondrial membrane organization; ISS:UniProtKB.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:UniProtKB.::GO:0006626; P:protein targeting to mitochondrion; ISS:UniProtKB.
14A0Q1Q0    294   ERA_CLONN GTPase Era OS=Clostridium novyi (st...1360.86     36.6     23     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
15B8I442    441   DER_CLOCE GTPase Der OS=H10). GN=der Synonyms...740.89     36.6     31     57
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
16Q0C441    510   DER_HYPNA GTPase Der OS=Hyphomonas neptunium ...930.93     36.6     26     46
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
17Q88VS0    302   ERA_LACPL GTPase Era OS=Lactobacillus plantar...1780.93     36.2     23     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
18B1HTJ0    305   ERA_LYSSC GTPase Era OS=Lysinibacillus sphaer...1141.3     35.8     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
19Q39T85    439   DER_GEOMG GTPase Der OS=Geobacter metalliredu...421.6     35.8     43     62
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
20Q811U4    741   MFN1_MOUSE Mitofusin-1 OS=Mus musculus (Mouse...2341.7     35.8     21     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0008053; P:mitochondrial fusion; IMP:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
21Q8IWA4    741   MFN1_HUMAN Mitofusin-1 OS=Homo sapiens (Human...1672     35.8     23     45GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
GO:0008053; P:mitochondrial fusion; IDA:BHF-UCL.
22O95140    757   MFN2_HUMAN Mitofusin-2 OS=Homo sapiens (Human...1672.2     35.8     25     43GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031306; C:intrinsic to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0008053; P:mitochondrial fusion; NAS:UniProtKB.::GO:0007006; P:mitochondrial membrane organization; IDA:UniProtKB.::GO:0051646; P:mitochondrion localization; IDA:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; IDA:UniProtKB.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; ISS:UniProtKB.::GO:0006626; P:protein targeting to mitochondrion; IDA:UniProtKB.
23Q89A14    462   DER_BUCBP GTPase Der OS=Buchnera aphidicola s...732.3     35.4     33     52
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
24C3L0M1    439   DER_CLOB6 GTPase Der OS=Clostridium botulinum...812.5     35     28     52
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
25P34617    645   GUF1_CAEEL Translation factor GUF1 homolog, m...2572.6     35.4     23     42GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006412; P:translation; IEA:UniProtKB-KW.
26Q80U63    757   MFN2_MOUSE Mitofusin-2 OS=Mus musculus (Mouse...1672.6     35.4     24     45GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031306; C:intrinsic to mitochondrial outer membrane; ISS:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0001825; P:blastocyst formation; IMP:MGI.::GO:0048593; P:camera-type eye morphogenesis; IMP:MGI.::GO:0008053; P:mitochondrial fusion; IMP:MGI.::GO:0007006; P:mitochondrial membrane organization; ISS:UniProtKB.::GO:0051646; P:mitochondrion localization; ISS:UniProtKB.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; ISS:UniProtKB.::GO:0006626; P:protein targeting to mitochondrion; ISS:UniProtKB.
27Q6LU45    493   DER_PHOPR GTPase Der OS=Photobacterium profun...792.8     35     27     43
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
28B9M914    441   DER_GEOSF GTPase Der OS=Geobacter sp. (strain...943.1     35     30     51
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
29Q0SS66    438   DER_CLOPS GTPase Der OS=Clostridium perfringe...723.1     35     29     56
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
30Q8XJK1    438   DER_CLOPE GTPase Der OS=Clostridium perfringe...723.1     35     29     56
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
31Q0TPJ9    438   DER_CLOP1 GTPase Der OS=Clostridium perfringe...723.1     35     29     56
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
records
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