Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR175W
Length:
315
Number of sequences:
5887
Description:
YBR175W SWD3 SGDID:S000000379, Chr II from 582408-583355, Genome Release 64-1-1, Verified ORF, "Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38123    315   SWD3_YEAST COMPASS component SWD3 OS=Saccharo...3150     650     100     100GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0051568; P:histone H3-K4 methylation; IDA:SGD.::GO:0000723; P:telomere maintenance; IMP:SGD.
2Q9D7H2    328   WDR5B_MOUSE WD repeat-containing protein 5B O...3023e-44     159     35     53
3Q498M4    334   WDR5_RAT WD repeat-containing protein 5 OS=Ra...3228e-44     158     34     51GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4P61965    334   WDR5_MOUSE WD repeat-containing protein 5 OS=...3228e-44     158     34     51GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5P61964    334   WDR5_HUMAN WD repeat-containing protein 5 OS=...3228e-44     158     34     51GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6Q2KIG2    334   WDR5_BOVIN WD repeat-containing protein 5 OS=...3229e-44     158     34     51GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7Q17963    376   TG125_CAEEL WD repeat-containing protein tag-...3001e-43     159     33     54GO:0005634; C:nucleus; IDA:WormBase.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051568; P:histone H3-K4 methylation; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
8Q5M786    334   WDR5_XENTR WD repeat-containing protein 5 OS=...2994e-43     156     35     53GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9A8X8C6    368   TG125_CAEBR WD repeat-containing protein tag-...3026e-43     157     34     53
10Q4V8C4    328   WDR5B_RAT WD repeat-containing protein 5B OS=...2992e-42     154     35     53
11Q5RE95    330   WDR5B_PONAB WD repeat-containing protein 5B O...3002e-42     154     35     53
12Q86VZ2    330   WDR5B_HUMAN WD repeat-containing protein 5B O...3003e-42     154     35     53
13Q9V3J8    361   WDS_DROME Protein will die slowly OS=Drosophi...3028e-42     154     33     52GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IPI:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:FlyBase.
GO:0051568; P:histone H3-K4 methylation; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.
14Q93847    395   YZLL_CAEEL Uncharacterized WD repeat-containi...3172e-36     139     32     50
15Q23256    501   YH92_CAEEL Uncharacterized WD repeat-containi...2865e-35     137     34     53
16Q54KL5    335   WDR5_DICDI WD repeat-containing protein 5 hom...1320.009     40.8     26     47GO:0035097; C:histone methyltransferase complex; ISS:dictyBase.
GO:0042393; F:histone binding; ISS:dictyBase.
GO:0051568; P:histone H3-K4 methylation; ISS:dictyBase.
17Q8W1K8    370   MUT11_CHLRE Protein Mut11 OS=Chlamydomonas re...1350.41     35.8     23     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
18O43017    380   SWD3_SCHPO Set1 complex component swd3 OS=Sch...2590.00002     49.3     22     38GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:PomBase.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0051568; P:histone H3-K4 methylation; IMP:PomBase.
19Q00808    1356   HETE1_PODAS Vegetative incompatibility protei...1230.000000002     62.4     35     52
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
20Q8YTC2    1258   Y2800_NOSS1 Uncharacterized WD repeat-contain...2950.00000000000004     76.6     24     42
GO:0043531; F:ADP binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:InterPro.
21P0CS42    433   LIS1_CRYNJ Nuclear distribution protein PAC1 ...982     33.9     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
22P0CS43    433   LIS1_CRYNB Nuclear distribution protein PAC1 ...982     33.9     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
23Q8YV57    1683   Y2124_NOSS1 Uncharacterized WD repeat-contain...2280.0000000000002     74.7     27     48
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
24O76734    579   TUP1_DICDI General transcriptional corepresso...1670.0000000003     64.7     31     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25Q54S79    942   WDR3_DICDI WD repeat-containing protein 3 hom...1300.35     36.2     27     46GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
26A8NEG8    434   LIS1_COPC7 Nuclear distribution protein PAC1 ...883.8     32.7     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
27Q8N136    415   WDR69_HUMAN Outer row dynein assembly protein...1170.0000002     55.8     28     49GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
28Q8YRI1    1526   YY46_NOSS1 Uncharacterized WD repeat-containi...2650.000000000007     69.7     26     44
29C4YFX2    511   TUP1_CANAW Transcriptional repressor TUP1 OS=...1660.00004     48.5     25     44
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30P0CY34    512   TUP1_CANAL Transcriptional repressor TUP1 OS=...1660.00004     48.5     25     44GO:0005625; C:soluble fraction; IDA:CGD.
GO:0016337; P:cell-cell adhesion; IMP:CGD.::GO:0071280; P:cellular response to copper ion; IMP:CGD.::GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0044409; P:entry into host; IMP:CGD.::GO:0051834; P:evasion or tolerance of defenses of other organism involved in symbiotic interaction; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0045827; P:negative regulation of isoprenoid metabolic process; IMP:CGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0009372; P:quorum sensing; IMP:CGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31P49695    742   PKWA_THECU Probable serine/threonine-protein ...1810.0008     44.7     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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