Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR175W
Length:
315
Number of sequences:
5887
Description:
YBR175W SWD3 SGDID:S000000379, Chr II from 582408-583355, Genome Release 64-1-1, Verified ORF, "Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
931Q4VBE8    431   WDR18_MOUSE WD repeat-containing protein 18 O...1850.017     40     26     44
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
932Q04724    770   TLE1_HUMAN Transducin-like enhancer protein 1...1172.3     33.9     28     48
GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IDA:UniProtKB.
GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; NAS:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
933Q8NHY2    731   RFWD2_HUMAN E3 ubiquitin-protein ligase RFWD2...980.019     40.4     26     47GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
934Q61666    1015   HIRA_MOUSE Protein HIRA OS=Mus musculus (Mous...890.019     40.4     29     54GO:0000790; C:nuclear chromatin; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007369; P:gastrulation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
935Q24371    769   L2DTL_DROME Protein lethal(2)denticleless OS=...2280.019     40.4     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
936Q26458    425   ESC_DROVI Polycomb protein esc OS=Drosophila ...1860.082     38.1     22     41GO:0000790; C:nuclear chromatin; ISS:UniProtKB.
GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
937Q5ZJW8    720   DTL_CHICK Denticleless protein homolog OS=Gal...800.14     37.7     31     51GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
938Q24572    430   CAF1_DROME Probable histone-binding protein C...1790.02     40     26     43GO:0033186; C:CAF-1 complex; IDA:FlyBase.::GO:0035098; C:ESC/E(Z) complex; IDA:FlyBase.::GO:0031523; C:Myb complex; IDA:FlyBase.::GO:0016581; C:NuRD complex; IDA:FlyBase.::GO:0016589; C:NURF complex; IPI:FlyBase.::GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0070822; C:Sin3-type complex; IDA:FlyBase.::GO:0005667; C:transcription factor complex; IPI:FlyBase.
GO:0035035; F:histone acetyltransferase binding; IPI:FlyBase.::GO:0042393; F:histone binding; IDA:FlyBase.::GO:0042826; F:histone deacetylase binding; IDA:FlyBase.::GO:0042803; F:protein homodimerization activity; IPI:FlyBase.
GO:0006342; P:chromatin silencing; IPI:FlyBase.::GO:0000910; P:cytokinesis; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0006281; P:DNA repair; TAS:FlyBase.::GO:0007307; P:eggshell chorion gene amplification; IC:FlyBase.::GO:0016573; P:histone acetylation; IDA:FlyBase.::GO:0070734; P:histone H3-K27 methylation; IC:GOC.::GO:0051567; P:histone H3-K9 methylation; IC:GOC.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:FlyBase.::GO:0006334; P:nucleosome assembly; IDA:FlyBase.::GO:0042766; P:nucleosome mobilization; IDA:FlyBase.::GO:0016584; P:nucleosome positioning; IDA:FlyBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:FlyBase.::GO:0007379; P:segment specification; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IDA:FlyBase.
939Q9R1A8    733   RFWD2_MOUSE E3 ubiquitin-protein ligase RFWD2...980.021     40     26     46GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
940Q32LP9    525   COR2A_BOVIN Coronin-2A OS=Bos taurus (Bovine)...1480.021     40     23     45GO:0015629; C:actin cytoskeleton; ISS:RefGenome.::GO:0017053; C:transcriptional repressor complex; ISS:RefGenome.
GO:0051015; F:actin filament binding; ISS:RefGenome.
GO:0030036; P:actin cytoskeleton organization; ISS:RefGenome.
941Q5FW06    457   DCA10_XENTR DDB1- and CUL4-associated factor ...1570.23     36.6     23     45GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:UniProtKB.
942Q24338    425   ESC_DROME Polycomb protein esc OS=Drosophila ...3340.034     39.3     21     39GO:0035098; C:ESC/E(Z) complex; IDA:FlyBase.::GO:0000790; C:nuclear chromatin; ISS:UniProtKB.
GO:0042802; F:identical protein binding; IPI:IntAct.
GO:0006342; P:chromatin silencing; IPI:FlyBase.::GO:0048096; P:chromatin-mediated maintenance of transcription; NAS:UniProtKB.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0070734; P:histone H3-K27 methylation; IMP:FlyBase.::GO:0051567; P:histone H3-K9 methylation; IC:GOC.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
943Q94AD8    539   FBW3_ARATH F-box/WD-40 repeat-containing prot...920.51     35.8     26     48
GO:0016036; P:cellular response to phosphate starvation; IMP:TAIR.
944Q8AVS9    457   DCA10_XENLA DDB1- and CUL4-associated factor ...1570.14     37.4     24     45GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:UniProtKB.
945Q6PFM9    677   WDR48_DANRE WD repeat-containing protein 48 O...1671.2     34.7     25     40GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
946P54319    795   PLAP_RAT Phospholipase A-2-activating protein...1143     33.5     22     48
947Q94AI7    1131   TPL_ARATH Protein TOPLESS OS=Arabidopsis thal...2620.024     40     23     37GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0042803; F:protein homodimerization activity; IPI:TAIR.
GO:0009867; P:jasmonic acid mediated signaling pathway; IMP:TAIR.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0010072; P:primary shoot apical meristem specification; IMP:TAIR.::GO:0009733; P:response to auxin stimulus; IPI:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0010051; P:xylem and phloem pattern formation; IGI:TAIR.
948A6SJ85    434   ATG18_BOTFB Autophagy-related protein 18 OS=c...1780.024     39.7     28     43GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
949Q08274    665   DMWD_MOUSE Dystrophia myotonica WD repeat-con...1330.024     40     22     41
950B9WHJ2    380   CIAO1_CANDC Probable cytosolic iron-sulfur pr...880.025     39.7     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
951Q9D565    1086   WDR64_MOUSE WD repeat-containing protein 64 O...1195     32.7     25     49
952O13166    761   TLE2_DANRE Protein groucho-2 OS=Danio rerio (...1140.76     35.4     22     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
953Q9R099    442   TBL2_MOUSE Transducin beta-like protein 2 OS=...1390.026     39.7     24     43
954Q6QEF8    472   CORO6_HUMAN Coronin-6 OS=Homo sapiens (Human)...1502.3     33.5     26     45GO:0015629; C:actin cytoskeleton; IBA:RefGenome.
GO:0051015; F:actin filament binding; IBA:RefGenome.
GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
955Q5TAQ9    597   DCAF8_HUMAN DDB1- and CUL4-associated factor ...930.027     39.7     28     45GO:0080008; C:CUL4 RING ubiquitin ligase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0016567; P:protein ubiquitination; IC:UniProtKB.
956Q38942    349   RAE1L_ARATH Rae1-like protein At1g80670 OS=Ar...1380.027     39.7     24     43GO:0080008; C:CUL4 RING ubiquitin ligase complex; IPI:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005635; C:nuclear envelope; IDA:TAIR.
GO:0005515; F:protein binding; IPI:TAIR.
957Q5U2M6    591   DCAF8_RAT DDB1- and CUL4-associated factor 8 ...930.027     39.7     28     45GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:UniProtKB.
958Q8QFR2    1013   HIRA_XENLA Protein HIRA OS=Xenopus laevis (Af...890.027     40     29     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
959Q0V8F1    915   CORO7_BOVIN Coronin-7 OS=Bos taurus (Bovine)....2730.027     40     23     42GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
960B4QB64    668   WDR48_DROSI WD repeat-containing protein 48 h...953.4     33.1     22     46
961Q9VAT2    621   DCA10_DROME DDB1- and CUL4-associated factor ...1140.055     38.9     31     46
records
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