Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR175W
Length:
315
Number of sequences:
5887
Description:
YBR175W SWD3 SGDID:S000000379, Chr II from 582408-583355, Genome Release 64-1-1, Verified ORF, "Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q9GL51    410   LIS1_PIG Platelet-activating factor acetylhyd...1130.0000009     53.5     28     49GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
92Q803D2    410   LIS1B_DANRE Lissencephaly-1 homolog B OS=Dani...770.86     35     27     44GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0045176; P:apical protein localization; IMP:ZFIN.::GO:0048854; P:brain morphogenesis; IMP:ZFIN.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0040023; P:establishment of nucleus localization; IMP:ZFIN.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045494; P:photoreceptor cell maintenance; IMP:ZFIN.::GO:0006810; P:transport; IEA:UniProtKB-KW.
93Q9UUG8    598   TUP12_SCHPO Transcriptional repressor tup12 O...1690.00003     49.3     28     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0042393; F:histone binding; IDA:PomBase.::GO:0003714; F:transcription corepressor activity; IDA:PomBase.
GO:0043156; P:chromatin remodeling in response to cation stress; IMP:PomBase.::GO:0006342; P:chromatin silencing; IMP:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
94Q5REG7    410   LIS1_PONAB Platelet-activating factor acetylh...2660.000000002     61.6     23     41GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
95Q4ICM0    464   LIS1_GIBZE Nuclear distribution protein PAC1 ...810.47     35.8     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
96B5X3Z6    410   LIS1A_SALSA Lissencephaly-1 homolog A OS=Salm...770.36     36.2     29     44GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
97Q5RD06    451   POC1B_PONAB POC1 centriolar protein homolog B...660.002     43.1     32     58GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.
GO:0042384; P:cilium assembly; ISS:UniProtKB.
98C4JZS6    446   LIS11_UNCRE Nuclear distribution protein PAC1...780.001     43.9     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
99Q01277    650   SCONB_NEUCR Probable E3 ubiquitin ligase comp...2720.0003     45.8     22     37
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
100O22212    554   PRP4_ARATH U4/U6 small nuclear ribonucleoprot...1820.025     39.7     23     42GO:0016607; C:nuclear speck; IDA:TAIR.
GO:0001709; P:cell fate determination; IMP:TAIR.::GO:0007267; P:cell-cell signaling; IMP:TAIR.::GO:0009560; P:embryo sac egg cell differentiation; IMP:TAIR.::GO:0008380; P:RNA splicing; IEA:InterPro.
101Q6ZMY6    472   WDR88_HUMAN WD repeat-containing protein 88 O...850.75     35     29     45
102Q8TC44    478   POC1B_HUMAN POC1 centriolar protein homolog B...1290.001     43.9     24     42GO:0005814; C:centriole; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.
GO:0042384; P:cilium assembly; IMP:UniProtKB.
103C5PFX0    471   LIS1_COCP7 Nuclear distribution protein PAC1 ...610.37     36.2     30     54GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
104Q9D994    303   WDR38_MOUSE WD repeat-containing protein 38 O...2570.000000000001     70.5     24     43
105Q4R8H1    569   TBL1X_MACFA F-box-like/WD repeat-containing p...900.0008     44.7     31     56GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
106Q9C1X1    854   PWP2_SCHPO Periodic tryptophan protein 2 homo...1350.42     36.2     23     42GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.::GO:0005732; C:small nucleolar ribonucleoprotein complex; ISS:PomBase.
GO:0030515; F:snoRNA binding; ISS:PomBase.
GO:0006364; P:rRNA processing; ISS:PomBase.
107Q9NDC9    404   LIS1_CAEEL Lissencephaly-1 homolog OS=Caenorh...2920.0000007     53.9     19     41GO:0005818; C:aster; IDA:WormBase.::GO:0005938; C:cell cortex; IDA:WormBase.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IDA:WormBase.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:WormBase.
GO:0005515; F:protein binding; IPI:WormBase.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051026; P:chiasma assembly; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0043652; P:engulfment of apoptotic cell; IMP:WormBase.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007018; P:microtubule-based movement; IMP:WormBase.::GO:0007100; P:mitotic centrosome separation; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0051225; P:spindle assembly; IMP:WormBase.::GO:0051932; P:synaptic transmission, GABAergic; IMP:WormBase.::GO:0048489; P:synaptic vesicle transport; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
108Q4RJN5    410   LIS1_TETNG Lissencephaly-1 homolog OS=nigrovi...775.1     32.3     27     43GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
109C5FWH1    461   LIS1_ARTOC Nuclear distribution protein PAC1 ...810.59     35.4     26     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
110Q05946    817   UTP13_YEAST U3 small nucleolar RNA-associated...1200.000007     51.2     28     52GO:0034388; C:Pwp2p-containing subcomplex of 90S preribosome; IDA:SGD.::GO:0032040; C:small-subunit processome; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030515; F:snoRNA binding; IPI:SGD.
GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
111P16649    713   TUP1_YEAST General transcriptional corepresso...1760.02     40.4     23     44GO:0017053; C:transcriptional repressor complex; IDA:SGD.
GO:0042393; F:histone binding; IDA:SGD.::GO:0042826; F:histone deacetylase binding; IDA:SGD.::GO:0036033; F:mediator complex binding; IDA:SGD.::GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0043486; P:histone exchange; IMP:SGD.::GO:0035955; P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0001198; P:negative regulation of mating-type specific transcription from RNA polymerase II promoter; IMP:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:SGD.::GO:0016584; P:nucleosome positioning; IDA:SGD.::GO:2000531; P:regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:2001020; P:regulation of response to DNA damage stimulus; IMP:SGD.::GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:SGD.::GO:0061392; P:regulation of transcription from RNA polymerase II promoter in response to osmotic stress; IMP:SGD.
112Q5ZMV7    313   WDR82_CHICK WD repeat-containing protein 82 O...3120.0000000000007     71.2     20     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
113Q6NV31    313   WDR82_DANRE WD repeat-containing protein 82 O...3120.0000000000008     71.2     21     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
114P38129    798   TAF5_YEAST Transcription initiation factor TF...2250.031     39.7     21     40GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.::GO:0005669; C:transcription factor TFIID complex; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0032947; F:protein complex scaffold; IMP:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0016573; P:histone acetylation; IDA:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IC:SGD.
115Q9UTC7    462   YIDC_SCHPO Uncharacterized WD repeat-containi...2090.003     42.7     23     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
116D3TLL6    411   LIS1_GLOMM Lissencephaly-1 homolog OS=Glossin...1360.00000009     56.6     28     51GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
117A8XZJ9    390   LIS1_CAEBR Lissencephaly-1 homolog OS=Caenorh...2290.000003     52     22     40GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
118B7PS00    411   LIS1_IXOSC Lissencephaly-1 homolog OS=Ixodes ...2450.00000002     58.9     24     43GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
119O74855    502   NLE1_SCHPO Ribosome assembly protein C18.05c ...1140.001     43.5     25     46GO:0005730; C:nucleolus; ISS:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0042254; P:ribosome biogenesis; ISS:PomBase.
120O60907    577   TBL1X_HUMAN F-box-like/WD repeat-containing p...900.0008     44.7     31     56GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
121A7S338    409   LIS1_NEMVE Lissencephaly-1 homolog OS=Nematos...2500.00001     50.1     22     40GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
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