Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR175W
Length:
315
Number of sequences:
5887
Description:
YBR175W SWD3 SGDID:S000000379, Chr II from 582408-583355, Genome Release 64-1-1, Verified ORF, "Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
901Q5I0B4    326   LST8_XENTR Target of rapamycin complex subuni...860.9     34.7     30     41GO:0005737; C:cytoplasm; ISS:UniProtKB.
902O14011    488   CWF8_SCHPO Pre-mRNA-splicing factor cwf8 OS=S...1270.012     40.8     27     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.::GO:0005681; C:spliceosomal complex; TAS:PomBase.::GO:0000151; C:ubiquitin ligase complex; TAS:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:PomBase.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; TAS:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:PomBase.
903A5D7H2    797   STRN3_BOVIN Striatin-3 OS=Bos taurus (Bovine)...1560.069     38.5     25     46GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
904Q13033    797   STRN3_HUMAN Striatin-3 OS=Homo sapiens (Human...1550.086     38.1     25     45GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0043234; C:protein complex; ISS:UniProtKB.
GO:0070016; F:armadillo repeat domain binding; IPI:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0051721; F:protein phosphatase 2A binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0032355; P:response to estradiol stimulus; ISS:UniProtKB.
905Q6PA72    326   LST8_XENLA Target of rapamycin complex subuni...860.93     34.7     30     41GO:0005737; C:cytoplasm; ISS:UniProtKB.
906Q9NZJ0    730   DTL_HUMAN Denticleless protein homolog OS=Hom...820.15     37.4     32     52GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB.::GO:0019985; P:translesion synthesis; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
907Q4IBR4    1046   HIR1_GIBZE Protein HIR1 OS=(Wheat head blight...1880.013     40.8     22     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
908Q6CSZ5    302   SEC13_KLULA Protein transport protein SEC13 O...1090.013     40.4     28     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
909Q16MY0    659   WDR48_AEDAE WD repeat-containing protein 48 h...1820.13     37.7     26     41
910Q5H7C0    499   CDC20_PIG Cell division cycle protein 20 homo...307.6     32     40     73GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.
911Q80ZK9    677   WDTC1_MOUSE WD and tetratricopeptide repeats ...1310.32     36.6     26     44GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0004857; F:enzyme inhibitor activity; IDA:MGI.::GO:0042393; F:histone binding; IPI:MGI.::GO:0042826; F:histone deacetylase binding; IPI:MGI.
GO:0055082; P:cellular chemical homeostasis; IMP:MGI.::GO:0032869; P:cellular response to insulin stimulus; IMP:MGI.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0008361; P:regulation of cell size; IMP:MGI.
912Q8N5D0    677   WDTC1_HUMAN WD and tetratricopeptide repeats ...1310.29     36.6     26     44GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
GO:0005515; F:protein binding; IPI:DFLAT.
913Q9UT85    507   YIPC_SCHPO Uncharacterized WD repeat-containi...1364.3     32.7     24     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0034657; C:GID complex; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0045721; P:negative regulation of gluconeogenesis; ISS:PomBase.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:PomBase.
914P90917    412   RBA1_CAEEL Probable histone-binding protein r...1291.3     34.3     26     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:WormBase.
GO:0001708; P:cell fate specification; IMP:WormBase.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0001703; P:gastrulation with mouth forming first; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016246; P:RNA interference; IMP:WormBase.::GO:0045138; P:tail tip morphogenesis; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
915Q756D0    445   YTM1_ASHGO Ribosome biogenesis protein YTM1 O...1522.9     33.1     22     43GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
916Q9Y263    795   PLAP_HUMAN Phospholipase A-2-activating prote...952     33.9     24     51
GO:0016005; F:phospholipase A2 activator activity; TAS:ProtInc.
GO:0006644; P:phospholipid metabolic process; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
917Q6BIR1    297   SEC13_DEBHA Protein transport protein SEC13 O...1120.015     40     29     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
918Q29KQ0    419   WDR12_DROPS Ribosome biogenesis protein WDR12...2170.015     40.4     24     40GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0070545; C:PeBoW complex; ISS:UniProtKB.
GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
919Q5R448    597   DCAF8_PONAB DDB1- and CUL4-associated factor ...930.016     40.4     28     45GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:UniProtKB.
920Q15291    538   RBBP5_HUMAN Retinoblastoma-binding protein 5 ...1930.19     37     22     42GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB.
GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0043627; P:response to estrogen stimulus; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
921B4GT01    419   WDR12_DROPE Ribosome biogenesis protein WDR12...2170.016     40.4     24     40GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0070545; C:PeBoW complex; ISS:UniProtKB.
GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
922Q9LXN4    1024   HIRA_ARATH Protein HIRA OS=Arabidopsis thalia...930.59     35.8     23     43GO:0005634; C:nucleus; IDA:TAIR.
GO:0005515; F:protein binding; IPI:TAIR.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0045814; P:negative regulation of gene expression, epigenetic; TAS:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
923O14186    846   YDSB_SCHPO Uncharacterized WD repeat-containi...1490.016     40.4     26     42GO:0005829; C:cytosol; IDA:PomBase.::GO:0005778; C:peroxisomal membrane; NAS:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
924Q9Y0T2    1247   FBXA_DICDI F-box/WD repeat-containing protein...580.016     40.8     38     66GO:0019005; C:SCF ubiquitin ligase complex; IDA:dictyBase.
GO:0005515; F:protein binding; IPI:dictyBase.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:dictyBase.
GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0045595; P:regulation of cell differentiation; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase.
925Q8VC03    897   EMAL3_MOUSE Echinoderm microtubule-associated...1250.016     40.4     29     43GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
926Q27GK7    1135   TPR4_ARATH Topless-related protein 4 OS=Arabi...1108.3     32     25     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:TAIR.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
927A8WGE3    480   COR2B_XENTR Coronin-2B OS=Xenopus tropicalis ...1060.49     35.8     22     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
928Q62440    770   TLE1_MOUSE Transducin-like enhancer protein 1...1172.3     33.9     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI.
GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
929Q8NI36    951   WDR36_HUMAN WD repeat-containing protein 36 O...1361.6     34.3     21     41GO:0032040; C:small-subunit processome; IEA:InterPro.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
930Q8BX09    538   RBBP5_MOUSE Retinoblastoma-binding protein 5 ...2260.19     37     23     43GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
931Q4VBE8    431   WDR18_MOUSE WD repeat-containing protein 18 O...1850.017     40     26     44
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
records
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