Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR175W
Length:
315
Number of sequences:
5887
Description:
YBR175W SWD3 SGDID:S000000379, Chr II from 582408-583355, Genome Release 64-1-1, Verified ORF, "Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
871Q0V320    332   EIF3I_PHANO Eukaryotic translation initiation...1860.007     41.2     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
872Q07141    748   TLE4_RAT Transducin-like enhancer protein 4 O...1140.053     38.9     23     46GO:0005634; C:nucleus; IDA:RGD.
GO:0003714; F:transcription corepressor activity; NAS:RGD.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
873Q9SJT9    1218   COPA2_ARATH Coatomer subunit alpha-2 OS=Arabi...1072.1     33.9     26     42GO:0030126; C:COPI vesicle coat; IEA:InterPro.::GO:0005829; C:cytosol; IDA:TAIR.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
874P58404    760   STRN4_MOUSE Striatin-4 OS=Mus musculus (Mouse...3070.13     37.7     20     36GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
875O16023    428   ESC_MUSDO Polycomb protein esc OS=Musca domes...930.098     37.7     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
876Q20059    683   WDR48_CAEEL WD repeat-containing protein 48 h...2000.008     41.6     22     41
877A8PD13    448   YTM1_COPC7 Ribosome biogenesis protein YTM1 O...1376.1     32.3     23     42GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
878P0CS38    881   HIR1_CRYNJ Protein HIR1 OS=ATCC MYA-565) (Fil...2020.27     36.6     25     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
879P0CS39    881   HIR1_CRYNB Protein HIR1 OS=(Filobasidiella ne...2020.27     36.6     25     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
880Q12834    499   CDC20_HUMAN Cell division cycle protein 20 ho...970.016     40.4     27     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0051488; P:activation of anaphase-promoting complex activity; IDA:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
881Q9LJR3    845   SPA3_ARATH Protein SPA1-RELATED 3 OS=Arabidop...1344.3     32.7     27     46GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004672; F:protein kinase activity; IEA:InterPro.
GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.
882Q7RZI0    1035   HIR1_NEUCR Protein hir-1 OS=1257 / FGSC 987)....1960.008     41.6     22     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
883Q803V5    326   LST8_DANRE Target of rapamycin complex subuni...861.7     33.9     30     41GO:0005737; C:cytoplasm; ISS:UniProtKB.
884Q17QU5    326   LST8_BOVIN Target of rapamycin complex subuni...1520.46     35.4     24     41GO:0005737; C:cytoplasm; ISS:UniProtKB.
885Q09019    674   DMWD_HUMAN Dystrophia myotonica WD repeat-con...1330.009     41.2     23     41
GO:0007126; P:meiosis; NAS:UniProtKB.
886Q62623    499   CDC20_RAT Cell division cycle protein 20 homo...308     32     40     73GO:0005813; C:centrosome; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.::GO:0050773; P:regulation of dendrite development; IMP:RGD.
887Q1DR81    473   CIAO1_COCIM Probable cytosolic iron-sulfur pr...860.009     41.2     34     51
888Q9JJ66    499   CDC20_MOUSE Cell division cycle protein 20 ho...970.057     38.5     25     49GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090129; P:positive regulation of synapse maturation; IDA:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; IDA:UniProtKB.::GO:0040020; P:regulation of meiosis; IGI:MGI.
889B4JPT9    419   WDR12_DROGR Ribosome biogenesis protein WDR12...2180.01     40.8     24     42GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0070545; C:PeBoW complex; ISS:UniProtKB.
GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
890A8Q2R5    660   WDR48_BRUMA WD repeat-containing protein 48 h...2090.027     39.7     23     41
891O13286    556   SRW1_SCHPO WD repeat-containing protein srw1 ...941.1     34.7     23     51GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; TAS:PomBase.::GO:0030996; P:cell cycle arrest in response to nitrogen starvation; IMP:PomBase.::GO:0008054; P:cyclin catabolic process; IMP:PomBase.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IC:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.
892O94289    713   LUB1_SCHPO Ubiquitin homeostasis protein lub1...1430.01     41.2     29     48GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0043130; F:ubiquitin binding; ISS:PomBase.
GO:0006281; P:DNA repair; ISS:PomBase.::GO:0016574; P:histone ubiquitination; NAS:PomBase.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:PomBase.
893Q9SV01    454   FBW4_ARATH F-box/WD-40 repeat-containing prot...1630.011     40.8     23     43
894Q9BVC4    326   LST8_HUMAN Target of rapamycin complex subuni...1520.67     35     23     42GO:0005829; C:cytosol; TAS:Reactome.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0032008; P:positive regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.
895P36104    329   SWD2_YEAST COMPASS component SWD2 OS=Saccharo...1220.38     35.8     24     45GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051568; P:histone H3-K4 methylation; IDA:SGD.::GO:0034729; P:histone H3-K79 methylation; IMP:SGD.::GO:0031124; P:mRNA 3'-end processing; IMP:SGD.::GO:0031126; P:snoRNA 3'-end processing; IMP:SGD.::GO:0000723; P:telomere maintenance; IMP:SGD.::GO:0030847; P:termination of RNA polymerase II transcription, exosome-dependent; IPI:SGD.::GO:0030846; P:termination of RNA polymerase II transcription, poly(A)-coupled; IPI:SGD.
896B1ANS9    1081   WDR64_HUMAN WD repeat-containing protein 64 O...1192     33.9     25     50
897P73595    334   Y1410_SYNY3 Uncharacterized WD repeat-contain...1230.18     37     24     43GO:0030288; C:outer membrane-bounded periplasmic space; IDA:UniProtKB.
898Q5AG86    383   CIAO1_CANAL Probable cytosolic iron-sulfur pr...880.012     40.8     34     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
899P58405    794   STRN3_RAT Striatin-3 OS=Rattus norvegicus (Ra...1000.055     38.9     27     52GO:0030425; C:dendrite; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0032403; F:protein complex binding; IDA:RGD.
GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IMP:RGD.::GO:0032355; P:response to estradiol stimulus; IDA:RGD.
900Q9ERG2    796   STRN3_MOUSE Striatin-3 OS=Mus musculus (Mouse...1000.05     38.9     27     52
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
901Q5I0B4    326   LST8_XENTR Target of rapamycin complex subuni...860.9     34.7     30     41GO:0005737; C:cytoplasm; ISS:UniProtKB.
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