Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR175W
Length:
315
Number of sequences:
5887
Description:
YBR175W SWD3 SGDID:S000000379, Chr II from 582408-583355, Genome Release 64-1-1, Verified ORF, "Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
721Q9DAW6    521   PRP4_MOUSE U4/U6 small nuclear ribonucleoprot...3100.002     43.1     22     35GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
722Q29HG9    315   LST8_DROPS Protein LST8 homolog OS=Drosophila...1332     33.5     23     41GO:0005737; C:cytoplasm; ISS:UniProtKB.
723P97260    1276   SCAP_CRIGR Sterol regulatory element-binding ...1820.0002     46.6     29     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006994; P:positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway; ISS:UniProtKB.::GO:0006993; P:sterol regulatory element binding protein import into nucleus involved in sterol depletion response; IMP:UniProtKB.
724Q5RKI0    606   WDR1_RAT WD repeat-containing protein 1 OS=Ra...1152.5     33.5     23     43GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
725Q7KWK5    514   PRP19_DICDI Pre-mRNA-processing factor 19 hom...1506.4     32.3     23     44GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; ISS:dictyBase.::GO:0000151; C:ubiquitin ligase complex; ISS:dictyBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:dictyBase.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:dictyBase.
726Q6CU55    439   LIS1_KLULA Nuclear distribution protein PAC1 ...2270.0003     45.8     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
727P14197    478   AAC3_DICDI WD repeat-containing protein AAC3 ...1750.44     35.8     21     39
728Q96WV5    1207   COPA_SCHPO Putative coatomer subunit alpha OS...1871.6     34.3     21     43GO:0030126; C:COPI vesicle coat; ISS:PomBase.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; ISS:PomBase.
729Q5ZL33    350   STRAP_CHICK Serine-threonine kinase receptor-...1980.067     38.1     24     42GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005102; F:receptor binding; ISS:AgBase.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:AgBase.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:AgBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
730Q12770    1279   SCAP_HUMAN Sterol regulatory element-binding ...1820.0003     46.2     27     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; NAS:UniProtKB.
GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0045541; P:negative regulation of cholesterol biosynthetic process; NAS:UniProtKB.::GO:0045716; P:positive regulation of low-density lipoprotein particle receptor biosynthetic process; NAS:UniProtKB.::GO:0006994; P:positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway; IMP:UniProtKB.
731C5DY07    444   LIS1_ZYGRC Nuclear distribution protein PAC1 ...1350.96     34.7     22     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
732Q4I7L0    423   HAT2_GIBZE Histone acetyltransferase type B s...1050.0003     45.8     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
733Q5E9A4    368   RAE1L_BOVIN mRNA export factor OS=Bos taurus ...800.001     43.5     31     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
734Q9W328    313   LST8_DROME Protein LST8 homolog OS=Drosophila...1234.5     32.3     24     42GO:0005737; C:cytoplasm; ISS:UniProtKB.
735Q9USR0    404   CKN1_SCHPO DNA excision repair protein ckn1 O...2920.0003     45.4     23     42GO:0005829; C:cytosol; IDA:PomBase.::GO:0070912; C:Ddb1-Ckn1 complex; IDA:PomBase.
GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:PomBase.
736O17468    1047   HIRA_DROME Protein HIRA homolog OS=Drosophila...1631.2     34.7     25     44GO:0001673; C:male germ cell nucleus; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.
GO:0006336; P:DNA replication-independent nucleosome assembly; IMP:FlyBase.::GO:0035042; P:fertilization, exchange of chromosomal proteins; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
737Q8SRK1    384   HAT2_ENCCU Histone acetyltransferase type B s...1510.0004     45.4     27     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
738Q7ZWF0    368   RAE1L_DANRE mRNA export factor OS=Danio rerio...830.004     42     28     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
739P87314    932   HIR1_SCHPO Protein hir1 OS=Schizosaccharomyce...1130.31     36.6     26     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0000417; C:HIR complex; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0003682; F:chromatin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003714; F:transcription corepressor activity; TAS:PomBase.
GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0006336; P:DNA replication-independent nucleosome assembly; TAS:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
740Q9Y3F4    350   STRAP_HUMAN Serine-threonine kinase receptor-...1981.8     33.9     24     43GO:0030054; C:cell junction; IDA:HPA.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
741O89053    461   COR1A_MOUSE Coronin-1A OS=Mus musculus (Mouse...1620.0004     45.4     27     45GO:0030864; C:cortical actin cytoskeleton; IBA:RefGenome.::GO:0001772; C:immunological synapse; IDA:MGI.::GO:0030027; C:lamellipodium; IBA:RefGenome.::GO:0001891; C:phagocytic cup; IBA:RefGenome.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0051015; F:actin filament binding; IDA:MGI.
GO:0007015; P:actin filament organization; IMP:MGI.::GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0048873; P:homeostasis of number of cells within a tissue; IMP:MGI.::GO:0030595; P:leukocyte chemotaxis; IMP:MGI.::GO:0051126; P:negative regulation of actin nucleation; IBA:RefGenome.::GO:0001845; P:phagolysosome assembly; IBA:RefGenome.::GO:0050918; P:positive chemotaxis; IBA:RefGenome.::GO:0030335; P:positive regulation of cell migration; IMP:MGI.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:0030833; P:regulation of actin filament polymerization; IMP:MGI.::GO:0008360; P:regulation of cell shape; IMP:MGI.::GO:0034097; P:response to cytokine stimulus; IMP:MGI.::GO:0043029; P:T cell homeostasis; IMP:MGI.::GO:0032796; P:uropod organization; IMP:MGI.
742Q8C570    368   RAE1L_MOUSE mRNA export factor OS=Mus musculu...800.001     43.9     31     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.
743P55735    322   SEC13_HUMAN Protein SEC13 homolog OS=Homo sap...737     32     37     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0012507; C:ER to Golgi transport vesicle membrane; TAS:Reactome.::GO:0031080; C:Nup107-160 complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.::GO:0048208; P:COPII vesicle coating; TAS:Reactome.::GO:0006886; P:intracellular protein transport; NAS:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
744Q5XIG8    350   STRAP_RAT Serine-threonine kinase receptor-as...1980.54     35.4     25     43GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
745P97865    318   PEX7_MOUSE Peroxisomal targeting signal 2 rec...780.35     35.8     23     55GO:0005829; C:cytosol; IDA:MGI.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0001958; P:endochondral ossification; IMP:MGI.::GO:0006635; P:fatty acid beta-oxidation; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0016558; P:protein import into peroxisome matrix; IMP:MGI.
746Q9Z1Z2    350   STRAP_MOUSE Serine-threonine kinase receptor-...1980.17     37     25     43GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005102; F:receptor binding; IDA:MGI.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:MGI.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
747Q5E959    350   STRAP_BOVIN Serine-threonine kinase receptor-...1090.008     41.2     25     46GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
748A7ETB3    667   MDV1_SCLS1 Mitochondrial division protein 1 O...900.95     35     23     49GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
749A5GFN6    368   RAEL1_PIG mRNA export factor OS=Sus scrofa (P...800.001     43.9     31     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
750Q8NA23    367   WDR31_HUMAN WD repeat-containing protein 31 O...1610.0005     45.1     23     44
751Q5RF99    368   RAEL1_PONAB mRNA export factor OS=Pongo abeli...800.0005     45.1     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
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