Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR175W
Length:
315
Number of sequences:
5887
Description:
YBR175W SWD3 SGDID:S000000379, Chr II from 582408-583355, Genome Release 64-1-1, Verified ORF, "Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
541Q3KQ62    314   WDR83_XENLA WD repeat domain-containing prote...1221.5     33.9     23     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
542Q8WWQ0    1821   PHIP_HUMAN PH-interacting protein OS=Homo sap...730.53     35.8     23     52GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005158; F:insulin receptor binding; NAS:UniProtKB.
GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; NAS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0045840; P:positive regulation of mitosis; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
543Q94BR4    523   PR19A_ARATH Pre-mRNA-processing factor 19 hom...783.8     33.1     26     47GO:0005730; C:nucleolus; IDA:TAIR.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0042742; P:defense response to bacterium; IGI:TAIR.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
544Q922V4    513   PLRG1_MOUSE Pleiotropic regulator 1 OS=Mus mu...1860.45     35.8     23     45GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
545Q54WA3    316   PEX7_DICDI Peroxisomal targeting signal 2 rec...1620.00007     47.4     25     44GO:0005777; C:peroxisome; ISS:dictyBase.
GO:0005053; F:peroxisome matrix targeting signal-2 binding; ISS:dictyBase.
GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro.
546Q5RAC9    607   A16L1_PONAB Autophagy-related protein 16-1 OS...2770.000003     52.4     22     42GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
547Q8VDD9    1821   PHIP_MOUSE PH-interacting protein OS=Mus musc...2024.4     33.1     20     40GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0045840; P:positive regulation of mitosis; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0001932; P:regulation of protein phosphorylation; IDA:UniProtKB.
548Q5A7Q3    389   PRP46_CANAL Pre-mRNA-splicing factor PRP46 OS...2311.2     34.3     24     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
549A6ZQL5    714   MDV1_YEAS7 Mitochondrial division protein 1 O...900.26     36.6     30     53GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
550Q9Y297    605   FBW1A_HUMAN F-box/WD repeat-containing protei...1030.00003     48.9     27     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
551Q5RCG7    434   AAMP_PONAB Angio-associated migratory cell pr...2210.00002     49.3     22     41GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0014909; P:smooth muscle cell migration; ISS:UniProtKB.
552Q13685    434   AAMP_HUMAN Angio-associated migratory cell pr...2210.00002     49.7     22     41GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008201; F:heparin binding; TAS:ProtInc.
GO:0001525; P:angiogenesis; NAS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0014909; P:smooth muscle cell migration; IEP:UniProtKB.
553Q2U5Z8    650   MDV1_ASPOR Mitochondrial division protein 1 O...860.076     38.5     24     53GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
554Q6CBI8    332   CIAO1_YARLI Probable cytosolic iron-sulfur pr...1620.000004     51.6     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
555Q5XGE2    515   UTP15_XENTR U3 small nucleolar RNA-associated...1420.89     35     26     43GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
556B3RNR8    313   CIAO1_TRIAD Probable cytosolic iron-sulfur pr...2001.4     33.9     26     38
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
557B2RZ17    454   FBXW2_RAT F-box/WD repeat-containing protein ...1750.0002     46.2     26     45
558A7TLU2    347   CIAO1_VANPO Probable cytosolic iron-sulfur pr...2270.1     37.7     19     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
559A8XJ40    306   SEC13_CAEBR Protein SEC13 homolog OS=Caenorha...1380.000004     51.2     33     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; ISS:UniProtKB.
GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
560Q5AXW3    654   MDV1_EMENI Mitochondrial division protein 1 O...2080.002     43.5     25     40GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
561A5DJX5    507   LIS1_PICGU Nuclear distribution protein PAC1 ...1341.9     33.9     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
562Q6KAU8    623   A16L2_MOUSE Autophagy-related protein 16-2 OS...3050.000004     51.6     20     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
563Q7YR70    435   AAMP_CANFA Angio-associated migratory cell pr...1780.17     37     23     44GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0014909; P:smooth muscle cell migration; ISS:UniProtKB.
564Q10272    446   IPI3_SCHPO Pre-rRNA-processing protein crb3/i...2530.000004     51.6     25     41GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0006364; P:rRNA processing; ISS:PomBase.
565Q29RH4    351   THOC3_BOVIN THO complex subunit 3 OS=Bos taur...2120.0002     46.2     22     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
566Q05583    330   CIAO1_YEAST Cytosolic iron-sulfur protein ass...1260.008     41.2     25     43GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0016226; P:iron-sulfur cluster assembly; IMP:SGD.::GO:0000055; P:ribosomal large subunit export from nucleus; IMP:SGD.::GO:0002098; P:tRNA wobble uridine modification; IMP:SGD.
567Q96J01    351   THOC3_HUMAN THO complex subunit 3 OS=Homo sap...2120.0002     46.2     22     38GO:0000346; C:transcription export complex; IDA:UniProtKB.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0046784; P:intronless viral mRNA export from host nucleus; IDA:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
568Q5F3D7    520   UTP15_CHICK U3 small nucleolar RNA-associated...1130.63     35.4     23     47GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
569Q60584    422   FBXW2_MOUSE F-box/WD repeat-containing protei...1750.0003     45.4     26     45GO:0005737; C:cytoplasm; IDA:MGI.
570A6ZYM0    330   CIAO1_YEAS7 Probable cytosolic iron-sulfur pr...1260.009     40.8     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
571Q8VE80    351   THOC3_MOUSE THO complex subunit 3 OS=Mus musc...2120.0002     46.2     22     38
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
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