Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR175W
Length:
315
Number of sequences:
5887
Description:
YBR175W SWD3 SGDID:S000000379, Chr II from 582408-583355, Genome Release 64-1-1, Verified ORF, "Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331B4QHG6    411   LIS1_DROSI Lissencephaly-1 homolog OS=Drosoph...2490.000001     52.8     21     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
332B4HSL3    411   LIS1_DROSE Lissencephaly-1 homolog OS=Drosoph...2490.000001     52.8     21     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
333Q7KNS3    411   LIS1_DROME Lissencephaly-1 homolog OS=Drosoph...2490.000001     52.8     21     39GO:0030424; C:axon; IDA:UniProtKB.::GO:0005938; C:cell cortex; IDA:FlyBase.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0005869; C:dynactin complex; IDA:FlyBase.::GO:0030286; C:dynein complex; IDA:FlyBase.::GO:0005828; C:kinetochore microtubule; IDA:FlyBase.::GO:0043025; C:neuronal cell body; IDA:UniProtKB.::GO:0031616; C:spindle pole centrosome; IDA:FlyBase.
GO:0045502; F:dynein binding; ISS:UniProtKB.
GO:0008088; P:axon cargo transport; IMP:FlyBase.::GO:0051299; P:centrosome separation; IMP:FlyBase.::GO:0030381; P:chorion-containing eggshell pattern formation; IMP:UniProtKB.::GO:0007303; P:cytoplasmic transport, nurse cell to oocyte; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:UniProtKB.::GO:0048142; P:germarium-derived cystoblast division; IMP:UniProtKB.::GO:0007294; P:germarium-derived oocyte fate determination; IMP:UniProtKB.::GO:0008298; P:intracellular mRNA localization; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; IMP:FlyBase.::GO:0051383; P:kinetochore organization; IMP:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:UniProtKB.::GO:0007405; P:neuroblast proliferation; IMP:UniProtKB.::GO:0030473; P:nuclear migration along microtubule; IGI:FlyBase.::GO:0007312; P:oocyte nucleus migration involved in oocyte dorsal/ventral axis specification; IMP:FlyBase.::GO:0030723; P:ovarian fusome organization; IMP:UniProtKB.::GO:0030510; P:regulation of BMP signaling pathway; IDA:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:FlyBase.::GO:0043143; P:regulation of translation by machinery localization; IMP:UniProtKB.::GO:0051225; P:spindle assembly; IMP:FlyBase.::GO:0019827; P:stem cell maintenance; IDA:FlyBase.
334Q5ZME8    513   SMU1_CHICK WD40 repeat-containing protein SMU...1900.000002     52.8     24     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
335Q09855    506   POF11_SCHPO F-box/WD repeat-containing protei...1690.00007     47.8     24     36GO:0005829; C:cytosol; IDA:PomBase.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
336P42527    1146   MHCKA_DICDI Myosin heavy chain kinase A OS=Di...1580.001     43.9     28     48GO:0005938; C:cell cortex; IDA:dictyBase.
GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0005524; F:ATP binding; IC:dictyBase.::GO:0016887; F:ATPase activity; IDA:dictyBase.::GO:0016905; F:myosin heavy chain kinase activity; IDA:dictyBase.::GO:0045159; F:myosin II binding; IPI:dictyBase.
GO:0051764; P:actin crosslink formation; IDA:dictyBase.::GO:0051017; P:actin filament bundle assembly; IDA:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0031037; P:myosin II filament disassembly; IDA:dictyBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0051260; P:protein homooligomerization; IDA:dictyBase.
337O42248    317   GBLP_DANRE Guanine nucleotide-binding protein...2690.00000001     58.9     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001525; P:angiogenesis; IMP:ZFIN.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; IMP:UniProtKB.::GO:0051302; P:regulation of cell division; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.::GO:0032880; P:regulation of protein localization; IMP:UniProtKB.
338Q54RP0    648   AGTA_DICDI UDP-galactose:fucoside alpha-3-gal...1930.019     40.4     25     45GO:0005737; C:cytoplasm; TAS:dictyBase.
GO:0004381; F:fucosylgalactoside 3-alpha-galactosyltransferase activity; IEA:EC.
GO:0006486; P:protein glycosylation; IDA:dictyBase.
339Q5RHI5    647   DTL_DANRE Denticleless protein homolog OS=Dan...2070.00000001     59.7     24     43GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:ZFIN.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
340B8M7Q5    667   SCONB_TALSN Probable E3 ubiquitin ligase comp...1840.0002     46.2     27     43
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
341Q6NRT3    513   SMU1_XENLA WD40 repeat-containing protein SMU...1900.000002     53.1     24     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
342O94620    340   CWF17_SCHPO Pre-mRNA-splicing factor cwf17 OS...1570.00001     49.7     26     45GO:0005681; C:spliceosomal complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IC:PomBase.
343B6Q4Z5    660   SCONB_PENMQ Probable E3 ubiquitin ligase comp...1840.00004     48.5     28     43
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
344Q54D08    304   LST8_DICDI Protein LST8 homolog OS=Dictyostel...1340.002     43.1     23     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0031932; C:TORC2 complex; IPI:dictyBase.
GO:0007190; P:activation of adenylate cyclase activity; IMP:dictyBase.::GO:0032148; P:activation of protein kinase B activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase.
345Q5I0B9    622   ATG16_XENTR Autophagy-related protein 16 OS=X...1860.004     42.4     22     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
346O13615    473   PRP46_SCHPO Pre-mRNA-splicing factor prp5 OS=...1980.24     36.6     22     40GO:0005681; C:spliceosomal complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IMP:PomBase.
347A7MB12    519   UTP15_BOVIN U3 small nucleolar RNA-associated...2240.00000002     58.9     25     43GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
348P25382    515   NLE1_YEAST Ribosome assembly protein 4 OS=Sac...1360.00005     48.1     28     48GO:0005730; C:nucleolus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0000027; P:ribosomal large subunit assembly; IMP:SGD.
349P49846    704   TAF5_DROME Transcription initiation factor TF...1650.000001     53.5     25     44GO:0000124; C:SAGA complex; IPI:FlyBase.::GO:0005669; C:transcription factor TFIID complex; IDA:FlyBase.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IDA:GOC.
350Q99KN2    339   CIAO1_MOUSE Probable cytosolic iron-sulfur pr...2060.00000002     58.2     26     43GO:0071817; C:MMXD complex; ISS:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:MGI.
GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:MGI.
351Q95RJ9    700   EBI_DROME F-box-like/WD repeat-containing pro...900.002     43.1     31     53GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0017053; C:transcriptional repressor complex; IGI:FlyBase.
GO:0003682; F:chromatin binding; IDA:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0042676; P:compound eye cone cell fate commitment; TAS:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IPI:GOC.::GO:0007219; P:Notch signaling pathway; TAS:FlyBase.::GO:0042461; P:photoreceptor cell development; IMP:FlyBase.::GO:0031065; P:positive regulation of histone deacetylation; IDA:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:FlyBase.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.
352Q9HAV0    340   GBB4_HUMAN Guanine nucleotide-binding protein...1510.0000004     54.3     26     48GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
353B6GZD3    464   LIS12_PENCW Nuclear distribution protein nudF...702.4     33.5     29     53GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
354B3MEY6    411   LIS1_DROAN Lissencephaly-1 homolog OS=Drosoph...2490.000002     52.4     21     38GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
355B4MY65    409   LIS1_DROWI Lissencephaly-1 homolog OS=Drosoph...1040.39     35.8     26     51GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
356Q09150    302   REC14_SCHPO Meiotic recombination protein rec...1950.15     37     24     41GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0055087; C:Ski complex; ISS:PomBase.
GO:0006402; P:mRNA catabolic process; ISS:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.
357B4JB43    326   EIF3I_DROGR Eukaryotic translation initiation...950.33     36.2     23     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
358P36408    347   GBB_DICDI Guanine nucleotide-binding protein ...1660.0000008     53.5     25     43GO:0005834; C:heterotrimeric G-protein complex; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0031682; F:G-protein gamma-subunit binding; IDA:dictyBase.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007190; P:activation of adenylate cyclase activity; TAS:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IDA:dictyBase.::GO:0032320; P:positive regulation of Ras GTPase activity; IMP:dictyBase.::GO:0030826; P:regulation of cGMP biosynthetic process; TAS:dictyBase.
359Q5RFQ3    918   PWP2_PONAB Periodic tryptophan protein 2 homo...1293.3     33.1     22     44GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
360Q5M7T1    339   CIAO1_RAT Probable cytosolic iron-sulfur prot...2060.00000003     57.8     26     43GO:0071817; C:MMXD complex; ISS:UniProtKB.
GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
361Q7ZV55    325   EIF3I_DANRE Eukaryotic translation initiation...916.8     32     25     48GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; ISS:UniProtKB.
records
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