Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR175W
Length:
315
Number of sequences:
5887
Description:
YBR175W SWD3 SGDID:S000000379, Chr II from 582408-583355, Genome Release 64-1-1, Verified ORF, "Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121A7S338    409   LIS1_NEMVE Lissencephaly-1 homolog OS=Nematos...2500.00001     50.1     22     40GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
122Q6GMD2    305   WDR61_XENLA WD repeat-containing protein 61 O...1070.21     36.6     24     43GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
123P87053    605   POF1_SCHPO F-box/WD repeat-containing protein...1820.0003     45.8     24     47GO:0000152; C:nuclear ubiquitin ligase complex; ISS:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0030674; F:protein binding, bridging; IPI:PomBase.
GO:0071276; P:cellular response to cadmium ion; IEP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IPI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
124Q1LV15    415   WDR69_DANRE Outer row dynein assembly protein...1140.0000009     53.5     26     52GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.::GO:0060285; P:ciliary cell motility; IMP:UniProtKB.::GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.::GO:0007368; P:determination of left/right symmetry; IMP:UniProtKB.
125Q5ZJH5    305   WDR61_CHICK WD repeat-containing protein 61 O...1420.03     39.3     25     38GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
126Q54LT8    293   STRAP_DICDI Serine-threonine kinase receptor-...1025.8     32     28     42
GO:0004872; F:receptor activity; ISS:dictyBase.
GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:dictyBase.
127Q2HBX6    454   LIS11_CHAGB Nuclear distribution protein PAC1...740.47     35.8     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
128Q4WT34    453   PRP46_ASPFU Pre-mRNA-splicing factor prp46 OS...2620.00000003     58.2     23     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
129O14727    1248   APAF_HUMAN Apoptotic protease-activating fact...865     32.7     26     51GO:0043293; C:apoptosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IDA:UniProtKB.::GO:0006952; P:defense response; IEA:InterPro.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:UniProtKB.::GO:0007399; P:nervous system development; TAS:ProtInc.
130Q2HJH6    358   SNR40_BOVIN U5 small nuclear ribonucleoprotei...2220.000003     52     25     41GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
131Q3Y8L7    446   WDR69_CHLRE Outer row dynein assembly protein...2590.0000000001     65.9     24     40GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0035086; C:flagellar axoneme; IEA:UniProtKB-SubCell.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.
132B4P7Q3    335   CIAO1_DROYA Probable cytosolic iron-sulfur pr...1370.01     40.8     28     43
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
133Q86TI4    376   WDR86_HUMAN WD repeat-containing protein 86 O...1960.00009     47.4     24     39
134Q9EPV5    1249   APAF_RAT Apoptotic protease-activating factor...950.91     35     29     49GO:0043293; C:apoptosome; IDA:RGD.
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IPI:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.
GO:0007568; P:aging; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0010659; P:cardiac muscle cell apoptotic process; IMP:RGD.::GO:0030154; P:cell differentiation; IEP:RGD.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:RGD.::GO:0006952; P:defense response; IEA:InterPro.::GO:0034349; P:glial cell apoptotic process; IEP:RGD.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0051260; P:protein homooligomerization; IDA:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.
135Q9GZS3    305   WDR61_HUMAN WD repeat-containing protein 61 O...1390.062     38.1     24     40GO:0016593; C:Cdc73/Paf1 complex; IDA:UniProtKB.::GO:0055087; C:Ski complex; IDA:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0080182; P:histone H3-K4 trimethylation; IMP:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; IMP:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
136B2AEZ5    464   LIS11_PODAN Nuclear distribution protein PAC1...2070.00001     50.1     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
137Q6PBD6    305   WDR61_XENTR WD repeat-containing protein 61 O...1910.00008     47     26     46GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
138Q6FL15    347   EIF3I_CANGA Eukaryotic translation initiation...2080.000000000004     69.7     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
139Q32LN7    305   WDR61_BOVIN WD repeat-containing protein 61 O...1370.17     37     23     40GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
140A2QP30    443   LIS1_ASPNC Nuclear distribution protein nudF ...1280.0002     46.2     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
141C4JPW9    459   LIS12_UNCRE Nuclear distribution protein PAC1...810.3     36.2     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
142P74598    348   Y1491_SYNY3 Uncharacterized WD repeat-contain...2930.000000000004     69.7     25     44GO:0030288; C:outer membrane-bounded periplasmic space; IDA:UniProtKB.
143Q9ERF3    305   WDR61_MOUSE WD repeat-containing protein 61 O...1371.9     33.5     22     39GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
144B6QC06    452   LIS12_PENMQ Nuclear distribution protein nudF...1270.002     43.1     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
145Q93794    587   SEL10_CAEEL F-box/WD repeat-containing protei...1810.0000001     56.6     26     45GO:0030424; C:axon; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:WormBase.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0046660; P:female sex differentiation; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IGI:UniProtKB.
146Q640J6    313   WD82A_XENLA WD repeat-containing protein 82-A...3120.000000000006     68.9     20     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
147A6RUL1    335   EIF3I_BOTFB Eukaryotic translation initiation...1070.33     36.2     21     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
148Q7K1Y4    335   CIAO1_DROME Probable cytosolic iron-sulfur pr...1370.014     40.4     28     43
GO:0005515; F:protein binding; IPI:IntAct.
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
149A0CH87    403   LIS12_PARTE Lissencephaly-1 homolog 2 OS=Para...1704     32.7     24     44GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
150Q7PS24    341   CIAO1_ANOGA Probable cytosolic iron-sulfur pr...1360.29     36.2     24     43
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
151Q96DI7    357   SNR40_HUMAN U5 small nuclear ribonucleoprotei...2200.000002     52     25     41GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005732; C:small nucleolar ribonucleoprotein complex; NAS:UniProtKB.::GO:0005682; C:U5 snRNP; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.
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