Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR170C
Length:
580
Number of sequences:
5887
Description:
YBR170C NPL4 SGDID:S000000374, Chr II from 578086-576344, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-binding protein involved in protein degradation; Cdc48p-Npl4p-Ufd1p complex participates in ER-associated degradation (ERAD) while Cdc48p-Npl4p-Vms1p complex participates in mitochondria-associated degradation (MAD)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P33755    580   NPL4_YEAST Nuclear protein localization prote...5800     1215     100     100GO:0034098; C:Cdc48p-Npl4p-Ufd1p AAA ATPase complex; IDA:SGD.::GO:0000837; C:Doa10p ubiquitin ligase complex; IDA:SGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0071629; P:cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0072671; P:mitochondria-associated protein catabolic process; IMP:SGD.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
2A7TTC4    568   NPL4_VANPO Nuclear protein localization prote...5770     823     67     80GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
3Q6FJI2    580   NPL4_CANGA Nuclear protein localization prote...5860     797     65     78GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
4Q6CLY1    596   NPL4_KLULA Nuclear protein localization prote...5960     764     61     76GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
5Q74ZJ1    563   NPL4_ASHGO Nuclear protein localization prote...5830     736     60     76GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
6A3GFS1    577   NPL4_PICST Nuclear protein localization prote...5850     569     49     66GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
7Q6BRJ9    566   NPL4_DEBHA Nuclear protein localization prote...5840     558     50     67GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
8A5DBC9    564   NPL4_PICGU Nuclear protein localization prote...5550     556     50     68GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
9A5DX93    600   NPL4_LODEL Nuclear protein localization prote...6080     553     47     66GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
10Q5AA50    598   NPL4_CANAL Nuclear protein localization prote...6130     540     47     65GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
11Q6C619    563   NPL4_YARLI Nuclear protein localization prote...5880     534     49     63GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
12A4RN19    669   NPL4_MAGO7 Nuclear protein localization prote...6153e-180     532     45     62GO:0005829; C:cytosol; ISS:PAMGO_MGG.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0030433; P:ER-associated protein catabolic process; ISS:PAMGO_MGG.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
13Q1DY54    657   NPL4_COCIM Nuclear protein localization prote...6132e-178     527     45     63GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
14A1D4X8    652   NPL4_NEOFI Nuclear protein localization prote...6072e-178     526     45     64GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
15Q4WKD7    652   NPL4_ASPFU Nuclear protein localization prote...6079e-178     525     45     64GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
16Q2URI8    652   NPL4_ASPOR Nuclear protein localization prote...6082e-176     521     45     63GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
17A2Q8R9    654   NPL4_ASPNC Nuclear protein localization prote...6008e-176     520     44     63GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
18A7EGK5    611   NPL4_SCLS1 Nuclear protein localization prote...6257e-175     516     43     62GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
19Q5BGN5    652   NPL4_EMENI Nuclear protein localization prote...6142e-171     508     44     62GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
20A1CS06    674   NPL4_ASPCL Nuclear protein localization prote...6293e-169     503     44     62GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
21Q7SH49    651   NPL4_NEUCR Nuclear protein localization prote...6139e-169     501     43     62GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
22P0C7N6    653   NPL4_PHANO Nuclear protein localization prote...6054e-167     497     43     61GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
23A6R538    642   NPL4_AJECN Nuclear protein localization prote...6143e-163     487     43     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
24Q9P780    572   NPL4_SCHPO Nuclear protein localization prote...5867e-156     466     42     59GO:0034098; C:Cdc48p-Npl4p-Ufd1p AAA ATPase complex; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
25P0CP31    693   NPL4_CRYNB Nuclear protein localization prote...6149e-123     384     34     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
26P0CP30    693   NPL4_CRYNJ Nuclear protein localization prote...6149e-123     384     34     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
27Q9ES54    608   NPL4_RAT Nuclear protein localization protein...5884e-108     343     35     56GO:0034098; C:Cdc48p-Npl4p-Ufd1p AAA ATPase complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.
GO:0043130; F:ubiquitin binding; IDA:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006944; P:cellular membrane fusion; IDA:HGNC.::GO:0007030; P:Golgi organization; IDA:HGNC.
28P60670    608   NPL4_MOUSE Nuclear protein localization prote...5875e-108     343     34     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; ISS:HGNC.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; ISS:HGNC.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006944; P:cellular membrane fusion; ISS:HGNC.::GO:0030433; P:ER-associated protein catabolic process; ISS:HGNC.::GO:0007030; P:Golgi organization; ISS:HGNC.
29Q8TAT6    608   NPL4_HUMAN Nuclear protein localization prote...5874e-106     338     34     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; ISS:HGNC.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; ISS:HGNC.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:HGNC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006944; P:cellular membrane fusion; ISS:HGNC.::GO:0030433; P:ER-associated protein catabolic process; ISS:HGNC.::GO:0007030; P:Golgi organization; ISS:HGNC.
30Q9VBP9    652   NPL4_DROME Nuclear protein localization prote...5215e-99     321     36     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
31Q54GD3    576   NPL4_DICDI Nuclear protein localization prote...1730.000000006     62.4     27     50GO:0005783; C:endoplasmic reticulum; ISS:dictyBase.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; ISS:dictyBase.
GO:0030433; P:ER-associated protein catabolic process; ISS:dictyBase.
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