Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR160W
Length:
298
Number of sequences:
5887
Description:
YBR160W CDC28 SGDID:S000000364, Chr II from 560078-560974, Genome Release 64-1-1, Verified ORF, "Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternately associates with G1 cyclins (CLNs) and G2/M cyclins (CLBs) which direct the CDK to specific substrates"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P49615    292   CDK5_MOUSE Cyclin-dependent kinase 5 OS=Mus m...2957e-111     330     56     72GO:0030424; C:axon; ISS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:MGI.::GO:0030175; C:filopodium; IDA:MGI.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0031594; C:neuromuscular junction; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; IDA:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:MGI.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0048148; P:behavioral response to cocaine; IMP:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007160; P:cell-matrix adhesion; IDA:MGI.::GO:0021954; P:central nervous system neuron development; IMP:MGI.::GO:0021697; P:cerebellar cortex formation; IMP:MGI.::GO:0022038; P:corpus callosum development; IMP:MGI.::GO:0048813; P:dendrite morphogenesis; IMP:MGI.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0006886; P:intracellular protein transport; IMP:MGI.::GO:0021819; P:layer formation in cerebral cortex; IMP:MGI.::GO:0008045; P:motor axon guidance; IMP:MGI.::GO:0045786; P:negative regulation of cell cycle; IMP:MGI.::GO:0046826; P:negative regulation of protein export from nucleus; IMP:MGI.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:MGI.::GO:0031914; P:negative regulation of synaptic plasticity; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IDA:MGI.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; IMP:MGI.::GO:0032801; P:receptor catabolic process; IMP:MGI.::GO:0043113; P:receptor clustering; IMP:MGI.::GO:0030334; P:regulation of cell migration; IMP:MGI.::GO:0061001; P:regulation of dendritic spine morphogenesis; IMP:UniProtKB.::GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IMP:MGI.::GO:0014044; P:Schwann cell development; IMP:MGI.::GO:0019233; P:sensory perception of pain; IMP:MGI.::GO:0033136; P:serine phosphorylation of STAT3 protein; IDA:MGI.::GO:0007519; P:skeletal muscle tissue development; IDA:MGI.::GO:0001963; P:synaptic transmission, dopaminergic; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI.
62Q02399    292   CDK5_BOVIN Cyclin-dependent kinase 5 OS=Bos t...2957e-111     330     56     72GO:0030424; C:axon; ISS:AgBase.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:AgBase.::GO:0030175; C:filopodium; ISS:AgBase.::GO:0030426; C:growth cone; ISS:AgBase.::GO:0030027; C:lamellipodium; ISS:AgBase.::GO:0031594; C:neuromuscular junction; ISS:AgBase.::GO:0005634; C:nucleus; ISS:AgBase.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; ISS:AgBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:AgBase.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0035173; F:histone kinase activity; TAS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:AgBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007160; P:cell-matrix adhesion; ISS:AgBase.::GO:0009790; P:embryo development; ISS:AgBase.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:AgBase.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.
63Q2PQN9    292   CDK5_GLOMM Cyclin-dependent kinase 5 homolog ...2972e-110     328     55     71
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.
64P51166    292   CDK5_XENLA Cyclin-dependent kinase 5 OS=Xenop...2953e-110     328     56     72GO:0030424; C:axon; ISS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0031594; C:neuromuscular junction; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005176; F:ErbB-2 class receptor binding; ISS:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0031175; P:neuron projection development; ISS:UniProtKB.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.
65Q03114    292   CDK5_RAT Cyclin-dependent kinase 5 OS=Rattus ...2954e-110     328     56     72GO:0030424; C:axon; IDA:UniProtKB.::GO:0030054; C:cell junction; TAS:RGD.::GO:0016533; C:cyclin-dependent protein kinase 5 holoenzyme complex; IDA:RGD.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0031594; C:neuromuscular junction; IDA:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
GO:0048675; P:axon extension; TAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:RGD.::GO:0009790; P:embryo development; IDA:UniProtKB.::GO:0051402; P:neuron apoptotic process; IMP:RGD.::GO:0006913; P:nucleocytoplasmic transport; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0045055; P:regulated secretory pathway; IMP:RGD.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0009611; P:response to wounding; IMP:RGD.::GO:0007519; P:skeletal muscle tissue development; TAS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; IMP:RGD.
66P23573    314   CDC2C_DROME Cell division control protein 2 c...2971e-109     327     56     72GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:FlyBase.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:FlyBase.::GO:0007259; P:JAK-STAT cascade; IPI:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
67Q38774    305   CDC2C_ANTMA Cell division control protein 2 h...3012e-109     327     56     71
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
68P54666    311   CC2H3_TRYBB Cell division control protein 2 h...2971e-108     325     52     72
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
69P48609    294   CDK5_DROME Cyclin-dependent kinase 5 homolog ...2971e-108     324     55     71GO:0016533; C:cyclin-dependent protein kinase 5 holoenzyme complex; IPI:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.
70Q8LG64    315   CKB22_ARATH Cyclin-dependent kinase B2-2 OS=A...3006e-108     323     53     71
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0009755; P:hormone-mediated signaling pathway; IEP:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:TAIR.::GO:0009934; P:regulation of meristem structural organization; IMP:TAIR.
71Q6C7U8    294   PHO85_YARLI Negative regulator of the PHO sys...2923e-106     318     54     73
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
72Q8LF80    313   CKB21_ARATH Cyclin-dependent kinase B2-1 OS=A...2971e-105     317     52     70GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:TAIR.::GO:0016572; P:histone phosphorylation; IDA:TAIR.::GO:0009755; P:hormone-mediated signaling pathway; IEP:TAIR.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:TAIR.::GO:0009934; P:regulation of meristem structural organization; IMP:TAIR.
73Q0J4I1    326   CKB21_ORYSJ Cyclin-dependent kinase B2-1 OS=O...2972e-105     317     53     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009524; C:phragmoplast; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
74Q38775    312   CDC2D_ANTMA Cell division control protein 2 h...3033e-105     316     51     69
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
75Q6FKD4    302   PHO85_CANGA Negative regulator of the PHO sys...3006e-105     315     54     71
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
76P17157    305   PHO85_YEAST Cyclin-dependent protein kinase P...3007e-105     315     53     72GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0050849; P:negative regulation of calcium-mediated signaling; IGI:SGD.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0016242; P:negative regulation of macroautophagy; IMP:SGD.::GO:0045936; P:negative regulation of phosphate metabolic process; IGI:SGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:SGD.::GO:0016239; P:positive regulation of macroautophagy; IMP:SGD.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IGI:SGD.::GO:0032880; P:regulation of protein localization; IDA:SGD.::GO:0031647; P:regulation of protein stability; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD.
77Q06309    301   CRK1_LEIME Cell division protein kinase 2 hom...3023e-104     313     52     70
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
78P54664    301   CC2H1_TRYCO Cell division control protein 2 h...3013e-103     310     52     71
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
79Q8SR86    296   CDK1_ENCCU Cyclin-dependent kinase 1 OS=Encep...2915e-103     310     52     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
80Q92241    304   PHO85_KLULA Negative regulator of the PHO sys...3001e-102     309     52     69
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
81O74456    288   PEF1_SCHPO Serine/threonine-protein kinase pe...2891e-101     306     53     72GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IGI:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.::GO:0007089; P:traversing start control point of mitotic cell cycle; IGI:PomBase.
82P38973    301   CC2H1_TRYBB Cell division control protein 2 h...3011e-101     306     50     70
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
83Q751E8    303   PHO85_ASHGO Negative regulator of the PHO sys...2984e-100     303     50     70
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
84O35832    451   CKD18_RAT Cyclin-dependent kinase 18 OS=Rattu...2953e-96     298     52     68
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
85P54665    345   CC2H2_TRYBB Cell division control protein 2 h...2911e-95     293     50     68
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
86Q00537    523   CDK17_HUMAN Cyclin-dependent kinase 17 OS=Hom...2951e-95     298     52     68
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
87Q00536    496   CDK16_HUMAN Cyclin-dependent kinase 16 OS=Hom...2945e-95     296     51     68
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
88Q04735    496   CDK16_MOUSE Cyclin-dependent kinase 16 OS=Mus...2941e-94     295     51     68
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
89Q04770    291   CDK2_ENTHI Cell division protein kinase 2 hom...2912e-94     288     49     67
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
90Q8K0D0    523   CDK17_MOUSE Cyclin-dependent kinase 17 OS=Mus...2954e-94     294     51     68
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
91O35831    523   CDK17_RAT Cyclin-dependent kinase 17 OS=Rattu...2951e-93     293     51     68
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
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